Antibody-Dependent Cellular Cytotoxicity and Skin Disease [PDF]
, 1985 Antibody dependent cellular cytotoxicity (ADCC) is a recently described mechanism of immunologic lysis in which cellular targets sensitized by specific antibodies are efficiently and selectively lysed by Fc receptor (FcR) bearing nonspecific effectors ...
David A. Norris +3 more
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Phosphorylation of the myosin IIA tailpiece regulates single myosin IIA molecule association with lytic granules to promote NK-cell cytotoxicity [PDF]
, 2011 Natural killer (NK) cells are innate immune lymphocytes that provide critical defense against virally infected and transformed cells. NK-cell cytotoxicity requires the formation of an F-actin rich immunologic synapse (IS), as well as the polarization of ...
Emily M. Mace +8 more
core +3 more sources
Target cell-dependent T cell-mediated lysis of vaccinia virus-infected cells [PDF]
, 1975 Vaccinia virus specific cytotoxicity against infected target cells was observed in vitro. Spleen lymphocytes from normal and immunized mice of the inbred strains C3H and DBA/2 were incubated with vaccinia virus-infected and non-infected 51Cr-labeled ...
Koszinowski, Ulrich H. +3 more
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Iranian Journal of Allergy, Asthma and Immunology, 2019 Stromal cell-derived factor-1 alpha (SDF-1α) has been shown to be up-regulated in a variety of malignancies. So that, its expression is associated with poor prognosis and invasiveness.
Alireza Mardomi +4 more
doaj +1 more source
Cytotoxicity of polycarbonate orthodontic brackets
Brazilian Journal of Oral Sciences, 2015 Aim: To assess the cytotoxicity of polycarbonate orthodontic brackets. Methods: Polycarbonate brackets from two different manufacturers, namely, Composite bracket (Morelli™) and Silkon Plus bracket (American Orthodontics™), were assessed.
Matheus Melo Pithon +6 more
doaj +1 more source
The cooperating mutation or “second hit” determines the immunologic visibility toward MYC-induced murine lymphomas [PDF]
, 2011 In Eμ-myc transgenic animals lymphoma formation requires additional genetic alterations, which frequently comprise loss of p53 or overexpression of BCL-2. We describe that the nature of the “second hit” affects the ability of the immune system to contain
Olivia Simma +18 more
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Cytotoxicity of Reparative Endodontic Cements on Human Periodontal Ligament Stem Cells
Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2022 Objective: To compare the cytotoxicity of commercial reparative endodontic cements on human periodontal ligament stem cells (hPDLSCs). Material and Methods: The culture of hPDLSCs was established.
Marlus da Silva Pedrosa +4 more
doaj
In vitro Cytotoxicity in Delayed-Type Hypersensitivity and Immunologic Tolerance.
Experimental Biology and Medicine, 1964 SummaryPicryl chloride was found to exert a lethal effect in vitro on leukocytes, principally lymphocytes, from guinea pigs exhibiting delayed-type skin reactivity to this hapten in the absence of antibody and complement. This reaction was found to be immunologically specific.
D M, LUBAROFF, R E, RITTS
openaire +2 more sources
IL-2 stimulated but not unstimulated NK cells induce selective disappearance of peripheral blood cells: concomitant results to a phase I/II study [PDF]
, 2011 In an ongoing clinical phase I/II study, 16 pediatric patients suffering from high risk leukemia/tumors received highly purified donor natural killer (NK) cell immunotherapy (NK-DLI) at day (+3) +40 and +100 post haploidentical stem cell transplantation.
Claudia Brehm +53 more
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The Biological Influence and Clinical Relevance of Polymorphism Within the NKG2D Ligands
Frontiers in Immunology, 2018 NKG2D is a major regulator of the activity of cytotoxic cells and interacts with eight different ligands (NKG2DL) from two families of MIC and ULBP proteins.
Jianmin Zuo, Fiyaz Mohammed, Paul Moss
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