Results 21 to 30 of about 54,012 (308)

Cytotoxicity and genotoxicity of calcium silicate-based cements on an osteoblast lineage

Brazilian Oral Research, 2016
Several calcium silicate-based biomaterials have been developed in recent years, in addition to Mineral Trioxide Aggregate (MTA). The aim of this study was to evaluate the cytotoxicity, genotoxicity and apoptosis/necrosis in human osteoblast cells (SAOS ...
Ana Lívia GOMES-CORNÉLIO, Elisandra Márcia RODRIGUES, Leticia Boldrin MESTIERI, Thaís de Oliveira Rodrigues Sanzovo FALCOSKI, Christiane Pienna SOARES, Juliane Maria GUERREIRO-TANOMARU, Carlos ROSSA JUNIOR, Mário TANOMARU FILHO   +7 more
doaj   +1 more source

Assessment of intracanal medications cytotoxicity on L929 fibroblast cells

Bioscience Journal, 2016
This study aimed to evaluate the cytotoxicity of intracanal medications on L929 fibroblast cells at different periods of observation. The following experimental groups were studied: calcium hydroxide with camphorated paramonochlorophenol and glycerin ...
Michelle de Paula Farias, Felipe de Souza Matos, Nayane Chagas Carvalho, Roque Pacheco de Almeida, Adriano Augusto Melo de Mendonça, Ricardo Luiz Cavalcanti de Albuquerque Júnior, Maria Amália Gonzaga Ribeiro   +6 more
doaj   +3 more sources

Altered distribution of mucosal NK cells during HIV infection. [PDF]

, 2012
The human gut mucosa is a major site of human immunodeficiency virus (HIV) infection and infection-associated pathogenesis. Increasing evidence shows that natural killer (NK) cells have an important role in control of HIV infection, but the mechanism(s ...
Alter, G, Berger, CT, Carrington, M, Deeks, SG, Diefenbach, T, Dugast, A-S, Estes, JD, Ghebremichael, M, Hunt, PW, Kwon, D, Liu, Q, Martin, JN, Sciaranghella, G, Sips, M   +13 more
core   +2 more sources

Metformin increases natural killer cell functions in head and neck squamous cell carcinoma through CXCL1 inhibition

Journal for ImmunoTherapy of Cancer, 2022
Background Metformin slows tumor growth and progression in vitro, and in combination with chemoradiotherapy, resulted in high overall survival in patients with head and neck cancer squamous cell carcinoma (HNSCC) in our phase 1 clinical trial ...
Maria A Lehn, Trisha M Wise-Draper, Shuchi Gulati, Vinita Takiar, Sarah Palackdharry, Mario Medvedovic, Timothy Stone, Joseph Curry, Vidhya Karivedu, McKenzie Crist, Benyamin Yaniv, Michael Borchers, Bethany Fuhrman, Audrey Crago, Ubaldo Martinez-Outschoorn   +14 more
doaj   +1 more source

DR-bearing T lymphocytes in thoracic duct lymph [PDF]

, 1981
T cells having DR antigens were shown to be present in high numbers in the thoracic duct lymph of patients undergoing long-term drainage. As drainage progresses the proportion of T DR cells in the lymph increases to levels as high as 70% at 6 weeks ...
Abo, Albrechtson, Billing, Boyle, Colombani, Evans, Foon, Franksson, Fu, Greaves, H. Takahashi, J.C. Cicciarelli, Johnson, Kaplan, Machleder, Matell, Medawar, P.I. Terasaki, R. Billing, Starzl, Starzl, Suciu-Foca, T. Starzl, T. Yamaguchi, Terasaki, Y. Iwaki   +25 more
core   +1 more source

Lung tumor microenvironment induces specific gene expression signature in intratumoral NK cells

Frontiers in Immunology, 2013
Natural Killer (NK) cells are able to recognize and kill tumor cells, however whether they contribute to tumor immunosurveillance is still debated. Our previous studies demonstrated the presence of NK cells in human lung tumors.
Mélanie eGillard-Bocquet, Mélanie eGillard-Bocquet, Mélanie eGillard-Bocquet, Charles eCaer, Charles eCaer, Charles eCaer, Nicolas eCagnard, Nicolas eCagnard, Lucile eCrozet, Lucile eCrozet, Lucile eCrozet, Mikael ePerez, Mikael ePerez, Mikael ePerez, Wolf Hervé eFridman, Wolf Hervé eFridman, Wolf Hervé eFridman, Catherine eSautes-fridman, Catherine eSautes-fridman, Catherine eSautes-fridman, Isabelle eCremer, Isabelle eCremer, Isabelle eCremer   +22 more
doaj   +1 more source

Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine

Biomaterials Research, 2023
Tissue-engineered decellularized extracellular matrix (ECM) scaffolds hold great potential to address the donor shortage as well as immunologic rejection attributed to cells in conventional tissue/organ transplantation.
Mohammadreza Kasravi, Armin Ahmadi, Amirhesam Babajani, Radman Mazloomnejad, Mohammad Reza Hatamnejad, Siavash Shariatzadeh, Soheyl Bahrami, Hassan Niknejad   +7 more
doaj   +1 more source

Immunological Changes after Cancer Treatment and Participation in an Exercise Program [PDF]

, 2003
Purpose: The purpose of this investigation was to evaluate the impact of undertaking peripheral blood stem cell transplantation (PBST) on T-cell number and function, and to determine the role of a mixed type, moderate intensity exercise program in ...
Andrykowski, Birk, Brenner, Brittenden, Chess, Cohen, Dimeo, Hannet, Henon, Keast, Laperriere, Laperriere, Molrine, Mosmann, Nieman, Nordon, Peters, Pyne, Rigsby, Shephard, Shevde, Spitzer, Talmadge, Uh, Weidemann, Winningham, Woods, Young-Moo   +27 more
core   +2 more sources

Cytotoxic and Immunologic Effects of Methotrexate in Psoriasis

Journal of Investigative Dermatology, 1990
Based on recent experience that Cyclosporin A, an immunosuppressive drug, produces marked improvement in psoriasis, possible immunomodulatory activities of methotrexate (MTX) have been reviewed to look for alternate mechanisms of MTX action in psoriasis. It is generally considered that the therapeutic results of MTX in psoriasis are related to a direct
Weinstein, Gerald D., Jeffes, Edward, McCullough, Jerry L.   +2 more
openaire   +2 more sources

Trypsin digest of cancer cells surface stimulates anti-tumor immune response better than cancer cells themselves [PDF]

, 2010
Antigens expressed on the surface of cancer cells are accessible targets for both humoral and cell-mediated immune responses, and are therefore potential candidates for vaccine development.
Balashova Elena, Petr Lokhov
core   +2 more sources