Results 21 to 30 of about 288,657 (306)

Cytotoxic and Immunologic Effects of Methotrexate in Psoriasis

Journal of Investigative Dermatology, 1990
Based on recent experience that Cyclosporin A, an immunosuppressive drug, produces marked improvement in psoriasis, possible immunomodulatory activities of methotrexate (MTX) have been reviewed to look for alternate mechanisms of MTX action in psoriasis. It is generally considered that the therapeutic results of MTX in psoriasis are related to a direct
Weinstein, Gerald D., Jeffes, Edward, McCullough, Jerry L.   +2 more
openaire   +2 more sources

Assessment of intracanal medications cytotoxicity on L929 fibroblast cells

Bioscience Journal, 2016
This study aimed to evaluate the cytotoxicity of intracanal medications on L929 fibroblast cells at different periods of observation. The following experimental groups were studied: calcium hydroxide with camphorated paramonochlorophenol and glycerin ...
Michelle de Paula Farias, Felipe de Souza Matos, Nayane Chagas Carvalho, Roque Pacheco de Almeida, Adriano Augusto Melo de Mendonça, Ricardo Luiz Cavalcanti de Albuquerque Júnior, Maria Amália Gonzaga Ribeiro   +6 more
doaj   +3 more sources

Cytotoxicity and genotoxicity of calcium silicate-based cements on an osteoblast lineage

Brazilian Oral Research, 2016
Several calcium silicate-based biomaterials have been developed in recent years, in addition to Mineral Trioxide Aggregate (MTA). The aim of this study was to evaluate the cytotoxicity, genotoxicity and apoptosis/necrosis in human osteoblast cells (SAOS ...
Ana Lívia GOMES-CORNÉLIO, Elisandra Márcia RODRIGUES, Leticia Boldrin MESTIERI, Thaís de Oliveira Rodrigues Sanzovo FALCOSKI, Christiane Pienna SOARES, Juliane Maria GUERREIRO-TANOMARU, Carlos ROSSA JUNIOR, Mário TANOMARU FILHO   +7 more
doaj   +1 more source

UV Photoprotection, Cytotoxicity and Immunology Capacity of Red Algae Extracts [PDF]

Molecules, 2019
This study was designed to evaluate the potential use of algal extracts in cosmeceuticals, including factors related to biosecurity. The aqueous crude extracts of Hydropuntia cornea and Gracilariopsis longissima showed a good photoprotective capacity (Sun Protection Factor, SPF) due to, among other reasons, the presence of five types of mycosporine ...
Félix Álvarez-Gómez, Nathalie Korbee, Virginia Casas-Arrojo, Roberto T. Abdala-Díaz, Félix L. Figueroa   +4 more
openaire   +3 more sources

Metformin increases natural killer cell functions in head and neck squamous cell carcinoma through CXCL1 inhibition

Journal for ImmunoTherapy of Cancer, 2022
Background Metformin slows tumor growth and progression in vitro, and in combination with chemoradiotherapy, resulted in high overall survival in patients with head and neck cancer squamous cell carcinoma (HNSCC) in our phase 1 clinical trial ...
Maria A Lehn, Trisha M Wise-Draper, Shuchi Gulati, Vinita Takiar, Sarah Palackdharry, Mario Medvedovic, Timothy Stone, Joseph Curry, Vidhya Karivedu, McKenzie Crist, Benyamin Yaniv, Michael Borchers, Bethany Fuhrman, Audrey Crago, Ubaldo Martinez-Outschoorn   +14 more
doaj   +1 more source

Lung tumor microenvironment induces specific gene expression signature in intratumoral NK cells

Frontiers in Immunology, 2013
Natural Killer (NK) cells are able to recognize and kill tumor cells, however whether they contribute to tumor immunosurveillance is still debated. Our previous studies demonstrated the presence of NK cells in human lung tumors.
Mélanie eGillard-Bocquet, Mélanie eGillard-Bocquet, Mélanie eGillard-Bocquet, Charles eCaer, Charles eCaer, Charles eCaer, Nicolas eCagnard, Nicolas eCagnard, Lucile eCrozet, Lucile eCrozet, Lucile eCrozet, Mikael ePerez, Mikael ePerez, Mikael ePerez, Wolf Hervé eFridman, Wolf Hervé eFridman, Wolf Hervé eFridman, Catherine eSautes-fridman, Catherine eSautes-fridman, Catherine eSautes-fridman, Isabelle eCremer, Isabelle eCremer, Isabelle eCremer   +22 more
doaj   +1 more source

Effect of size, shape, and surface modification on cytotoxicity of gold nanoparticles to human Hep-2 and canine MDCK cells [PDF]

, 2012
There have been increasing interests in applying gold nanoparticles in biological research, drug delivery, and therapy. As the interaction of gold nanoparticles with cells relies on properties of nanoparticles, the cytotoxicity is complex and still under
Li, Wenqin, Xu, Dan, Chen, Yu, Zhang, Yinan, Yu, Jun   +4 more
core   +4 more sources

Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine

Biomaterials Research, 2023
Tissue-engineered decellularized extracellular matrix (ECM) scaffolds hold great potential to address the donor shortage as well as immunologic rejection attributed to cells in conventional tissue/organ transplantation.
Mohammadreza Kasravi, Armin Ahmadi, Amirhesam Babajani, Radman Mazloomnejad, Mohammad Reza Hatamnejad, Siavash Shariatzadeh, Soheyl Bahrami, Hassan Niknejad   +7 more
doaj   +1 more source

Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells [PDF]

, 2010
Background - Surface charge and oxidative stress are often hypothesized to be important factors in cytotoxicity of nanoparticles. However, the role of these factors is not well understood.
Nynke M Evers, Gerrit M Alink, Marcelis, A.T.M., Alink, G.M., Antonius TM Marcelis, Evers, N.M., Xue Jiang, Laura HJ de Haan, Rietjens, I.M.C.M., Zuilhof, H., Laura H. J. DE Haan, Ivonne MCM Rietjens, Jiang, X., Sourav Bhattacharjee, Antonius T. M. Marcelis, Han Zuilhof, Haan, L.H.J., de, Nynke M. Evers, Bhattacharjee, S., Ivonne M. C. M. Rietjens, Gerrit M. Alink   +20 more
core   +1 more source

High content analysis to determine cytotoxicity of the antimicrobial peptide, melittin and selected structural analogs [PDF]

, 2011
Antimicrobial peptides (AMPs) are naturally occurring entities with potential as pharmaceutical candidates and/or food additives. They are present in many organisms including bacteria, insects, fish and mammals.
O\u27Brien, Peter J., David J. Brayden, Baird, Alan W., Peter J. O’Brien, Marc Devocelle, Devocelle, Marc, Sam Maher, Alan W. Baird, Maher, Sam, Edwin G. Walsh, Walsh, Edwin G., O'Brien, Peter J., Brayden, David James   +12 more
core   +1 more source