Results 101 to 110 of about 1,578,267 (386)

Antioxidant Properties and Oxidative Transformation of Different Chromone Derivatives

Molecules, 2017
Nowadays, there is an increase in the application of natural products for the prevention of different disorders or adjuvant substances next to pharmacological treatment. Phytochemicals include different chromone derivatives, which possess a wide spectrum
Evelin Csepanyi, Peter Szabados-Furjesi, Attila Kiss-Szikszai, Lisa M. Frensemeier, Uwe Karst, Istvan Lekli, David D. Haines, Arpad Tosaki, Istvan Bak   +8 more
doaj   +1 more source

Synthesis and characterization of silver nanoparticle-decorated cobalt nanocomposites (Co@AgNPs) and their density-dependent antibacterial activity [PDF]

Royal Society Open Science, 2019
Magnetic cores loaded with metallic nanoparticles can be promising nano-carriers for successful drug delivery at infectious sites. We report fabrication, characteristic analysis and in vitro antibacterial performance of nanocomposites comprising cobalt ...
Zakia Kanwal, Muhammad Akram Raza, Saira Riaz, Saher Manzoor, Asima Tayyeb, Imran Sajid, Shahzad Naseem   +6 more
doaj   +1 more source

Tumor-associated and immunochemotherapy-dependent long-term alterations of the peripheral blood NK cell compartment in DLBCL patients [PDF]

, 2015
Natural Killer (NK) cells are a key component of tumor immunosurveillance and thus play an important role in rituximab-dependent killing of lymphoma cells via an antibody-dependent cellular cytotoxicity (ADCC) mechanism.
Battella, Simone, Cecere, Francesca, DI NAPOLI, Arianna, Eleonora, Alma, LA SCALEIA, Raffaella, M., Christina Cox, Mainiero, Fabrizio, Monarca, Bruno, Palmieri, Gabriella, Pelliccia, Sabrina, Porzia, Alessandra, Ruco, Luigi, Santoni, Angela, Zingoni, Alessandra   +13 more
core   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Cytotoxicity of Dental Alloys

Česká Stomatologie a Praktické Zubní Lékařství, 2007
The paper presented cytotoxicity testing procedure in vitro of chosen nickel - chromium dental alloys - Remanium G soft, Wiron 99, Wirolloy a Heraenium NA. Direct contact test and extract test were used.
L. Vavřičková, T. Dostálová, D. Vahalová, J. Šrámková, J. Ulrichová   +4 more
doaj  

Synthesis and In Vitro Cytotoxic Properties of Polycarbo-Substituted 4-(Arylamino)quinazolines

Molecules, 2016
Herein, we describe the synthesis of novel unsymmetrical polycarbo-substituted 4-anilinoquinazolines derived from the 2-aryl-6-bromo-8-iodoquinazolines via one-pot three-step reaction sequences involving initial amination and subsequent double cross ...
Hugues Kamdem Paumo, Tshepiso Jan Makhafola, Malose Jack Mphahlele   +2 more
doaj   +1 more source

Induction of IL 2 receptor expression and cytotoxicity of thymocytes by stimulation with TCF1 [PDF]

, 1985
We investigated the role of T cell cytotoxicity inducing factor 1 (TCF1) in the induction of a cytotoxic T cell response. We found that help-deficient thymocyte cultures supplied with saturating amounts of purified IL 2 did not develop CTL in a 5-day ...
Diamantstein, T., Dröge, W., Falk, Werner, Kaltmann, B., Katzer, B., Krammer, P. H., Männel, D. N.   +6 more
core  

The biogenic amines putrescine and cadaverine show in vitro cytotoxicity at concentrations that can be found in foods

Scientific Reports, 2019
Putrescine and cadaverine are among the most common biogenic amines (BA) in foods, but it is advisable that their accumulation be avoided. Present knowledge about their toxicity is, however, limited; further research is needed if qualitative and ...
B. del Rio, B. Redruello, D. Linares, V. Ladero, P. Ruas-Madiedo, María Fernández, M. Martín, M. Álvarez   +7 more
semanticscholar   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

The monoclonal antibody nBT062 conjugated to maytansinoids has potent and selective cytotoxicity against CD138 positive multiple myeloma cells _in vitro_ and _in vivo_ [PDF]

, 2008
CD138 (Syndecan1) is highly expressed on multiple myeloma (MM) cells. In this study, we examined the anti-MM effect of murine/human chimeric CD138-specific monoclonal antibody (mAb) nBT062 conjugated with highly cytotoxic maytansinoid derivatives _in ...
Benjamin Dä, Christoph Uherek, Diana Cristea, Frank Osterroth, Giulia Perrone, Hiroshi Ikeda, Hiroshi Yasui, Kenneth C. Anderson, Loredana Santo, Mariateresa Fulciniti, Nikhil C. Munshi, Noopur S. Raje, Paul Richardson, Robert J. Lutz, Samantha Pozzi, Silkie Aigner, Sonia Vallet, Tanyel Kiziltepe, Teru Hideshima, Yu-Tzu Tai, Yutaka Okawa   +20 more
core   +1 more source