Results 81 to 90 of about 1,629,625 (355)

α-Hexylcinnamaldehyde synergistically increases doxorubicin cytotoxicity towards human cancer cell lines [PDF]

, 2016
α-Hexylcinnamaldehyde (HCA), a compound derived from cinnamaldehyde, was evaluated for its potential chemosensitizing ...
DI GIACOMO, Silvia, DI SOTTO, Antonella, El Readi, Mahmoud Zaki, Mazzanti, Gabriela, Wink, Michael   +4 more
core  

Identification of Cytotoxic Flavor Chemicals in Top-Selling Electronic Cigarette Refill Fluids. [PDF]

, 2019
We identified the most popular electronic cigarette (EC) refill fluids using an Internet survey and local and online sales information, quantified their flavor chemicals, and evaluated cytotoxicities of the fluids and flavor chemicals.
Hua, My, Luo, Wentai, McWhirter, Kevin J, Omaiye, Esther E, Pankow, James F, Talbot, Prue   +5 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Cytotoxicity induced by Aeromonas schubertii is orchestrated by a unique set of type III secretion system effectors

Veterinary Research
The type III secretion system (T3SS) is an important virulence factor of Gram-negative bacteria, including the genus Aeromonas, which represents a diverse group of aquatic bacteria.
Hana Michova, Jan Pliva, Anezka Jirsova, David Jurnecka, Jana Kamanova   +4 more
doaj   +1 more source

Phytochemical Screening and Biological Activities of Lippia multiflora Moldenke

Molecules
Lippia multiflora Moldenke is widely used in Angola, on the African continent, and beyond for the treatment of many health conditions such as hypertension, enteritis, colds, gastrointestinal disturbances, stomachaches, jaundice, coughs, fevers, nausea ...
Dorcas Tlhapi, Ntsoaki Malebo, Idah Tichaidza Manduna, Monizi Mawunu, Ramakwala Christinah Chokwe   +4 more
doaj   +1 more source

Postbiotic metabolites produced by Lactobacillus plantarum strains exert selective cytotoxicity effects on cancer cells

BMC Complementary and Alternative Medicine, 2019
BackgroundLactobacillus plantarum, a major species of Lactic Acid Bacteria (LAB), are capable of producing postbiotic metabolites (PM) with prominent probiotic effects that have been documented extensively for rats, poultry and pigs. Despite the emerging
Li-Oon Chuah, H. Foo, T. Loh, Noorjahan Banu Mohammed Alitheen, S. Yeap, Nur Elina Abdul Mutalib, Raha Abdul Rahim, K. Yusoff   +7 more
semanticscholar   +1 more source

The role of copper in disulfiram-induced toxicity and radiosensitization of cancer cells [PDF]

, 2013
<p>Disulfiram has been used for several decades in the treatment of alcoholism. It now shows promise as an anti-cancer drug and radiosensitizer. Proposed mechanisms of action include the induction of oxidative stress and inhibition of proteasome ...
Ballangrud, Børup, Cen, Cohen, Hald, Maris, Sullivan, Yu, Yuhas   +8 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Dianthus superbus L. (QM) Extract-Assisted Silver Nanoparticle Gelatin Films with Antioxidant and Antimicrobial Properties for Fresh Fruit Preservation

Foods
We synthesized QM-AgNPs (Dianthus superbus L.-AgNPs, Qu Mai-AgNPs) by an economical and environmentally friendly method using Dianthus superbus L. extract as a reducing and stabilizing agent.
Chenwei Zhang, Yao Li, Yue Huo, Hongtao Wang, Dandan Wang   +4 more
doaj   +1 more source

CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes. [PDF]

, 1992
Engagement of the CD3/T cell antigen receptor complex on small, resting T cells is insufficient to trigger cell-mediated cytotoxicity or to induce a proliferative response.
Azuma, M, Buck, D, Cayabyab, M, Lanier, LL, Phillips, JH   +4 more
core   +1 more source