Results 81 to 90 of about 712,474 (313)

In Vitro Effect of Fungal Chitosan on Tumoral Cells and Microbial Cultures

Proceedings, 2019
The ability of marine chitosan to be processed as films. [...]
Simona Savin, Loredana-Ștefania Antohi, Anca Oancea, Agnes Toma, Ana-Maria Stanciuc, Florin Oancea, Oana Craciunescu   +6 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Synergistic cytotoxicity of homoharringtonine and etoposide in acute myeloid leukemia cells involves disrupted antioxidant defense [PDF]

, 2019
Jingjing Zhang,1,* Huayun Geng,2,* Ling Liu,1 Hao Zhang1 1Department of Hematology, Affiliated Hospital of Jining Medical University, Jining 272029, Shandong Province, China; 2Department of Hematology, Dongchangfu People’s Hospital of Liaocheng ...
Liu L, Zhang J, Geng H, Zhang H
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Investigating the Anticancer Potential of Chitosan Nanoparticles: In Vitro Assessment on TP-53 and PC-3 Cell Lines

Medical Journal of Babylon
Background: The increased threat of cancer is a critical challenge due to the absence of absolute treatment that eradicates this disease. Chitosan nanoparticles (CS NPs) offer promising opportunities for the development of anticancer medicines ...
Sama Jawad Al-Zuwaini, Hawraa Jawad Kadhim, Amer Al-Nafiey, Ali Hussein Al-Marzoqi, Mohammad Golbashy   +4 more
doaj   +1 more source

Heterocycles and a Sorbicillinoid from the Coral-Derived Fungus Penicillium chrysogenum

Marine Drugs
A detailed chemical study of the culture of a coral-derived fungus Penicillium chrysogenum resulted in the isolation and identification of four new aromatic heterocycles chrysoquinazolinones A–B (1–2) and chrysobenzothiazoles A–B (3–4), along with a new ...
Junjie Yang, Yuan Zong, Cili Wang, Kai Li, Yue Zhang, Pinglin Li   +5 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Paclitaxel-Loaded, Pegylated Carboxylic Graphene Oxide with High Colloidal Stability, Sustained, pH-Responsive Release and Strong Anticancer Effects on Lung Cancer A549 Cell Line

Pharmaceutics
Background: Graphene Oxide (GO) has shown great potential in biomedical applications for cancer therapeutics. The biosafety and stability issues of GO in biological media have been addressed by functionalization with polyethylene glycol (PEG).
Athina Angelopoulou, Myria Papachristodoulou, Efstathia Voulgari, Andreas Mouikis, Panagiota Zygouri, Dimitrios P. Gournis, Konstantinos Avgoustakis   +6 more
doaj   +1 more source

Antibacterial N-Arylcinnamamides as Anti-inflammatory Agents

Proceedings, 2019
A series of ring-substituted N-arylcinnamamides was prepared, characterized, and investigatedfor their antimicrobial efficacy in detail [...]
Jiri Kos, Lubos Danisovic, Zuzana Varchulova Novakova, Radoslav Zamborsky, Ferdinand Devinsky, Josef Jampilek   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

In vitro cytotoxicity mechanisms [PDF]

, 1999
bookConsiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome / CNR - Consiglio Nazionale delle ...
Istituto Superiore di Sanita', Rome (Italy)
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