Results 71 to 80 of about 805,987 (302)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Natural mineral particles are cytotoxic to rainbow trout gill epithelial cells in vitro [PDF]

, 2014
Worldwide increases in fluvial fine sediment are a threat to aquatic animal health. Fluvial fine sediment is always a mixture of particles whose mineralogical composition differs depending on the sediment source and catchment area geology.Nonetheless ...
Pietsch, Constanze, Michel, C., Herzog, S., De Capitani, C., Christian de Capitani, Pietsch, C., Simon Herzog, Burkhardt-Holm, Patricia, Patricia Burkhardt-Holm (592071), Constanze Pietsch, Christian Michel (159009), Patricia Burkhardt-Holm, de Capitani, Christian, Herzog, Simon, Burkhardt-Holm, P., Simon Herzog (592069), Christian de Capitani (592070), Michel, Christian, Constanze Pietsch (592072), Christian Michel, Pietsch, Constanze (author), Herzog, Simon (author), de Capitani, Christian (author), Michel C, Burkhardt-Holm, Patricia (author), Herzog S, de Capitani C, Burkhardt-Holm P, Michel, Christian (author), Pietsch C   +29 more
core   +2 more sources

Identification of the Cytotoxic Transglutaminase from Mycobacterium spp. That Is Involved in RIPK1 Activation

Molecules
Although the global incidence of tuberculosis has declined in recent years, tuberculosis remains a major global public health challenge. The Mycobacterium tuberculosis complex (MTBC) including M. tuberculosis, M. bovis, M. microti, etc., is the deadliest
Xinting Zhang, Yikai Zhang, Xiao Feng, Yueying Wang, Si-Shang Li, Mei-Yi Yan, Yi-Cheng Sun, Qi Jin, Feng Jiang   +8 more
doaj   +1 more source

Antioxidant Properties and Cytoprotective Effect Against H₂O₂-Induced Cytotoxicity in Mouse Fibroblasts Cells (L-929) of Horseradish Leaves

Proceedings, 2019
Horseradish (Armoracia rusticana L.) is a perennial plant from the Brassicaceae family native toEurope and Asia, and globally widespread through cultivation [...]
Ramona-Daniela Păvăloiu, Fawzia Sha’at, Corina Bubueanu, Georgeta Neagu, Cristina Hlevca, Mousa Sha’at, Gheorghe Nechifor   +6 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The Combination Effect of Chemotherapy Drug with Febuxostat and Curcumin on Colon Cancer Cell line (LS174T)

Medical Journal of Babylon
Background: Colorectal cancers are the 3rd highest commonly discovered form of cancer worldwide. The outcomes of various studies have revealed that cancer cells growth has been affected in response to treatment.
Ali M. Jaafar Abdulsahib, Rana Ayad Ghaleb, Nisreen Jalal Mohammed   +2 more
doaj   +1 more source

Ultrasound and microwave extraction from Moringa oleifera Lam.: Characterization and antiproliferative effect

International Journal of Secondary Metabolite
Moringa oleifera has been a focus of interest because of the different properties (anticancer, antioxidant, etc.) that have been attributed to this plant.
Raúl Rodríguez-herrera, Adriana Carolina Flores-gallegos, Juan Alberto Ascacio Valdes, Aide Saenz-galindo, Diana Salazar Sanchez, Rosario Estrada, Cecilia Esparza   +6 more
doaj   +1 more source

In Vitro Effect of Fungal Chitosan on Tumoral Cells and Microbial Cultures

Proceedings, 2019
The ability of marine chitosan to be processed as films. [...]
Simona Savin, Loredana-Ștefania Antohi, Anca Oancea, Agnes Toma, Ana-Maria Stanciuc, Florin Oancea, Oana Craciunescu   +6 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Investigating the Anticancer Potential of Chitosan Nanoparticles: In Vitro Assessment on TP-53 and PC-3 Cell Lines

Medical Journal of Babylon
Background: The increased threat of cancer is a critical challenge due to the absence of absolute treatment that eradicates this disease. Chitosan nanoparticles (CS NPs) offer promising opportunities for the development of anticancer medicines ...
Sama Jawad Al-Zuwaini, Hawraa Jawad Kadhim, Amer Al-Nafiey, Ali Hussein Al-Marzoqi, Mohammad Golbashy   +4 more
doaj   +1 more source