Results 71 to 80 of about 712,474 (313)

Evaluation of In Vitro Anti-Proliferative Activity of St. John’s Wort (Hypericum perforatum Linn.) Plant Extract on Cervix Adenocarcinoma

Proceedings, 2017
St. John’s wort (Hypericum perforatum L.) is a medicinal plant used for many diseases. Hypericum perforatum has strong historical background about the therapeutic potential.
Rana Kavurmacı, Serap Yalcin
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Cytotoxicity of orthodontic elastics: In vitro investigation with on L929 mouse fibroblasts [PDF]

test the hypothesis that there is no difference in the cytotoxicity among natural latex elastics of different manufacturers using a L929 cell line culture. Methods: Different latex intraoral elastics (I.D. = 5/16", 4.5 oz.) were tested.
Rogério Lacerda dos Santos, Matheus Melo Pithon, Fernanda Otaviano Martins, Maria Teresa Villela Romanos
core  

Cytotoxicity Test of Sponge Amnion on BHK-21 Fibroblast Cell [PDF]

, 2018
Biomaterials that can be used to accelerate wound healing is the amniotic membrane that contains growth hormone. In its use, amniotic membrane tends to be difficult to use because of their sheets form.
Anita Yuliati, Annisa Noor Ragilia, Elly Munadziroh   +2 more
core  

Identification of the Cytotoxic Transglutaminase from Mycobacterium spp. That Is Involved in RIPK1 Activation

Molecules
Although the global incidence of tuberculosis has declined in recent years, tuberculosis remains a major global public health challenge. The Mycobacterium tuberculosis complex (MTBC) including M. tuberculosis, M. bovis, M. microti, etc., is the deadliest
Xinting Zhang, Yikai Zhang, Xiao Feng, Yueying Wang, Si-Shang Li, Mei-Yi Yan, Yi-Cheng Sun, Qi Jin, Feng Jiang   +8 more
doaj   +1 more source

Antioxidant Properties and Cytoprotective Effect Against H₂O₂-Induced Cytotoxicity in Mouse Fibroblasts Cells (L-929) of Horseradish Leaves

Proceedings, 2019
Horseradish (Armoracia rusticana L.) is a perennial plant from the Brassicaceae family native toEurope and Asia, and globally widespread through cultivation [...]
Ramona-Daniela Păvăloiu, Fawzia Sha’at, Corina Bubueanu, Georgeta Neagu, Cristina Hlevca, Mousa Sha’at, Gheorghe Nechifor   +6 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Extensive evaluations of the cytotoxic effects of gold nanoparticles [PDF]

, 2014
Background: Many in vitro studies have revealed that the interference of dye molecules in traditional nanoparticlecytotoxicity assays results in controversial conclusions.
Gwo-Dong Roam, Pin Ju Chueh, Yi-Hui Lee, Zih-Ming Zeng, Hsin-Fang Tu, Show-Mei Chuang, Shi-Kwun Wang, Ruei-Yue Liang   +7 more
core   +1 more source

The Combination Effect of Chemotherapy Drug with Febuxostat and Curcumin on Colon Cancer Cell line (LS174T)

Medical Journal of Babylon
Background: Colorectal cancers are the 3rd highest commonly discovered form of cancer worldwide. The outcomes of various studies have revealed that cancer cells growth has been affected in response to treatment.
Ali M. Jaafar Abdulsahib, Rana Ayad Ghaleb, Nisreen Jalal Mohammed   +2 more
doaj   +1 more source

Ultrasound and microwave extraction from Moringa oleifera Lam.: Characterization and antiproliferative effect

International Journal of Secondary Metabolite
Moringa oleifera has been a focus of interest because of the different properties (anticancer, antioxidant, etc.) that have been attributed to this plant.
Raúl Rodríguez-herrera, Adriana Carolina Flores-gallegos, Juan Alberto Ascacio Valdes, Aide Saenz-galindo, Diana Salazar Sanchez, Rosario Estrada, Cecilia Esparza   +6 more
doaj   +1 more source