Results 101 to 110 of about 805,987 (302)

Cytotoxicity results.

, 2018
Cytotoxicity results.
M. Iqbal Choudhary (598049), Maria Yousuf (6053417), Zaheer Ul-Haq (3764533), Nimra Naveed Shaikh (3778396)   +3 more
core   +1 more source

Pharmacokinetic and cytotoxicity properties.

, 2020
Pharmacokinetic and cytotoxicity properties.
Gretchen Ehrenkaufer (8605254), Joseph DeRisi (30467), Jolyn Gisselberg (8605266), Pengyang Li (4449448), Conor R. Caffrey (113916), Anjan Debnath (352163), Upinder Singh (29923), Christopher D. Huston (8605275), Erin E. Stebbins (8605257), Ellen Yeh (207853), Steven C. Wang (8605269), Bo Wang (86769), Matthew S. Moser (8605263), Monica M. Kangussu-Marcolino (8605260), Ludovica Monti (1484272), Corin V. White (5644118), Ana Hervella Company (8605272)   +16 more
core   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Assessment of environmental safety and protective efficacy of O-antigen deficient DIVA capable Salmonella Enteritidis against chicken salmonellosis

Poultry Science
: In this study, we incorporated deletion of the O-antigen ligase gene to an attenuated Salmonella Enteritidis (SE) strain, JOL919 (SE PS; Δlon ΔcpxR), using the Lambda-Red recombination method and evaluated the safety and immunological aspects of the ...
Amal Senevirathne, Chamith Hewawaduge, John Hwa Lee   +2 more
doaj   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Size-dependent cytotoxicity of Fe3O4 nanoparticles induced by biphasic regulation of oxidative stress in different human hepatoma cells

, 2016
Yuexia Xie,1,2,* Dejun Liu,3,* Chenlei Cai,1,* Xiaojing Chen,1 Yan Zhou,1 Liangliang Wu,1 Yongwei Sun,3 Huili Dai,1,2 Xianming Kong,1,2 Peifeng Liu1,2 1Central Laboratory, 2State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute ...
Cai C, Wu L, Xie Y, Liu P, Chen X, Liu D, Zhou Y, Sun Y, Kong X, Dai H   +9 more
core  

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Cytotoxicity profile of the isolated constituents using MTT cytotoxicity assay.

, 2014
IC50 values are indicated as the mean ± SD of three independent experiments.BEZ-235 was used as positive control.Cytotoxicity profile of the isolated constituents using MTT cytotoxicity assay.
Pyare Lal Sangwan (644198), Mushtaq Ahmad Qurishi (644199), Javid Ahmad Banday (644197), Surrinder Koul (644200), Nisar Ahmad Dangroo (644195), Saleem Farooq (644193), Dev Priya (644196), Shakeel-u-Rehman (644194), Ajit Kumar Saxena (644201)   +8 more
core   +1 more source

Chiral phthalimides against penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus: molecular docking and in vitro analysis

Frontiers in Pharmacology
Staphylococcus aureus (S. aureus) is a commensal bacterium and an opportunistic pathogen causing a wide variety of infections ranging from localized skin and soft tissue infections to life-threatening severe bacteremia, osteomyelitis, endocarditis ...
Aamina Azam Khan, Momin Khan, Sher Wali Khan, Nayyer Siddique, Rimsha Abid, Shandana Zulfiqar, Sidra Rahman, Muhammad Ali   +7 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source