Results 101 to 110 of about 1,629,625 (355)

Assessment of Potential Toxic Effects of Fungicide Fludioxonil on Human Cells and Aquatic Microorganisms

Toxics
Fludioxonil is a widely used fungicide that is frequently used to combat fungal plant diseases. Consequently, excessive concentrations of fludioxonil may enter and accumulate over time in aquatic systems, harming (micro) organisms in several ways.
Maria Antonopoulou, Anna Tzamaria, Sotiris Papas, Ioanna Efthimiou, Dimitris Vlastos   +4 more
doaj   +1 more source

Antiradical Activities and Cytotoxic Effects of Phlomis Brevibracteata Turrill on SK-HEP-1 Adenocarcinoma Cell Line

Proceedings, 2018
The present study investigates the total phenol amount, radical scavenging and anticancer activity of methanolic extract of Phlomis brevibracteata Turrill (PBT) leaves; an endemic plant of North Cyprus.
Imge Kunter, Niloofar Zabib, Kelly Randmae, Mahshid Dabeshlim, Muberra Kosar   +4 more
doaj   +1 more source

Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity

Cell Death and Disease, 2017
Interferon gamma (IFNγ) is a key moderator of cell-mediated immunity with diverse, mainly pro-inflammatory actions on immunocytes and target tissue. Recent studies have shown it may enhance anti-tumor and antiviral effects of CD8 T cells.
P. Bhat, G. Leggatt, N. Waterhouse, I. Frazer   +3 more
semanticscholar   +1 more source

Uptake and cytotoxicity of citrate-coated gold nanospheres : comparative studies on human endothelial and epithelial cells [PDF]

, 2012
The use of gold nanoparticles (AuNPs) for diagnostic applications and for drug and gene-delivery is currently under intensive investigation. For such applications, biocompatibility and the absence of cytotoxicity of AuNPs is essential. Although generally
Couraud, Pierre-Olivier, Freese, Christian, Gibson, Matthew I., Kirkpatrick, C. J. (C. James), Romero, Ignacio A., Uboldi, Chiara, Unger, Ronald E., Weksler, Babette B.   +7 more
core   +7 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Enhancing Antioxidant and Cytotoxic Properties of CeO₂ Through Silver Decoration: A Study on Ag@CeO₂ Nanocomposites

Nanomaterials
In this study, silver-decorated cerium oxide (Ag@CeO2) nanoparticles were synthesized through a simple mixing and pyrolysis process to enhance their antioxidant and antitumor properties.
Chen Yang, Jingjing He, Siying Chen, Qiuping Li, Xuexia Lin   +4 more
doaj   +1 more source

Evaluation of In Vitro Anti-Proliferative Activity of St. John’s Wort (Hypericum perforatum Linn.) Plant Extract on Cervix Adenocarcinoma

Proceedings, 2017
St. John’s wort (Hypericum perforatum L.) is a medicinal plant used for many diseases. Hypericum perforatum has strong historical background about the therapeutic potential.
Rana Kavurmacı, Serap Yalcin
doaj   +1 more source

In Vitro Cytotoxicity and Cell Viability Assays: Principles, Advantages, and Disadvantages

Genotoxicity - A Predictable Risk to Our Actual World, 2017
Cytotoxicity is one of the most important indicators for biological evaluation in vitro studies. In vitro, chemicals such as drugs and pesticides have different cytotoxicity mechanisms such as destruction of cell membranes, prevention of protein ...
Özlem Sultan Aslantürk
semanticscholar   +1 more source

Evaluation of Cytotoxicity and Genotoxicity of Acacia aroma Leaf Extracts [PDF]

, 2014
Acacia aroma, native plant from San Luis, Argentina, is commonly used as antiseptic and for healing of wounds. The present study was conducted to investigate the in vitro cytotoxicity and genotoxicity of hot aqueous extract (HAE) and ethanolic extract ...
Alcaraz, María Luciana, Cangiano, Maria de Los Angeles, Escobar, Franco Matias, Laciar, Analia Liliana, Mattana, Claudia Maricel, Sabini, C., Sabini, Liliana Ines, Sosa, A.   +7 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source