Inhibition of Induction of Rat Liver Tyrosine Aminotransferase by d-Galactosamine
Abstract 1. An injection of d-galactosamine at the same time as an injection of dexamethasone inhibits the increase of rat liver tyrosine aminotransferase activity normally observed following injection of dexamethasone alone. The galactosamine-mediated inhibition is dose dependent: a 50% inhibition of the increase of enzyme activity is observed at 10 ...
R D, Reynolds, W, Reutter
openaire +2 more sources
Diosgenyl 2-amino-2-deoxy-β-D-galactopyranoside: synthesis, derivatives and antimicrobial activity
The synthesis of diosgenyl 2-amino-2-deoxy-β-D-galactopyranoside is presented for the first time. This synthetic saponin was transformed into its hydrochloride as well as N-acyl, 2-ureido, N-alkyl, and N,N-dialkyl derivatives.
Henryk Myszka +6 more
doaj +1 more source
Growing evidence has shown that gut microbiome is a key factor involved in liver health. Therefore, gut microbiota modulation with probiotic bacteria, such as Saccharomyces boulardii, constitutes a promising therapy for hepatosis. In this study, we aimed
Lei Yu +12 more
doaj +1 more source
The Protective Effect of Cordycepin on D-Galactosamine/Lipopolysaccharide-Induced Acute Liver Injury
As the major active ingredient of Cordyceps militaris, cordycepin (3′-deoxyadenosine) has been well documented to alleviate inflammation and oxidative stress both in vitro and in vivo. To explore the potential protective effect of cordycepin in fulminant
Jin Li +3 more
doaj +1 more source
Short-term fasting attenuates lipopolysaccharide/D-galactosamine-induced acute liver failure through Sirt1-autophagy signaling in mice. [PDF]
Long B, Tao H, Tong S, Wang X, Yin W.
europepmc +1 more source
Preventive Effect of 6-shogaol on D-galactosamine Induced Hepatotoxicity Through NF-?B/MAPK Signaling Pathway in Rats. [PDF]
Zong X +6 more
europepmc +1 more source
Protective effects of glutamine on lipopolysaccharide/D-galactosamine-induced fulminant hepatitis in mice. [PDF]
Yang M +7 more
europepmc +1 more source
Deficiency of Ninjurin1 attenuates LPS/D-galactosamine-induced acute liver failure by reducing TNF-α-induced apoptosis in hepatocytes. [PDF]
Kim MW +7 more
europepmc +1 more source
Gasdermin D Inhibitor Necrosulfonamide Alleviates Lipopolysaccharide/D-galactosamine-induced Acute Liver Failure in Mice. [PDF]
Wu YL, Ou WJ, Zhong M, Lin S, Zhu YY.
europepmc +1 more source
Integrated Analysis of Gut Microbiome and Liver Metabolome to Evaluate the Effects of Fecal Microbiota Transplantation on Lipopolysaccharide/D-galactosamine-Induced Acute Liver Injury in Mice. [PDF]
Yuan C +7 more
europepmc +1 more source

