Results 51 to 60 of about 24,218 (173)

Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science

open access: yesMass Spectrometry Reviews, Volume 45, Issue 4, Page 829-850, July/August 2026.
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song   +3 more
wiley   +1 more source

Hepatoprotective activity of Dypsis lutescens against D-galactosamine-induced hepatotoxicity in rats and its phytoconstituents

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2019
Objective: To isolate and identify the polyphenolic constituents of Dypsis lutescens, and evaluate the hepatoprotective activity of the ethanolic extract of Dypsis lutescens leaves.
Mai M El-Ghonemy   +7 more
doaj   +1 more source

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen   +6 more
wiley   +1 more source

Metabolic Dysfunction‐Associated Fatty Liver Disease: From Pathogenesis to Treatment

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Extracellular vesicles play a crucial role in interorgan crosstalk of adipose–liver and gut–liver axes and hold potential as therapeutic targets and drug delivery systems for metabolic dysfunction‐associated fatty liver disease (MAFLD). Abbreviations: AT: adipose tissue; EVs: extracellular vesicles; HL: healthy liver; NAFL: nonalcoholic fatty liver ...
Zhifu Cui   +5 more
wiley   +1 more source

High density lipoprotein subpopulations from galactosamine-treated rats and their transformation by lecithin:cholesterol acyltransferase

open access: yesJournal of Lipid Research, 1991
It is known that an acute hepatotoxicity is produced in rats by intraperitoneal administration of galactosamine; a consequence of this treatment is a marked deficiency of lecithin:cholesterol acyltransferase (LCAT) activity in the plasma compartment.
JE Matsuura, JB Swaney
doaj   +1 more source

Atherosclerosis: Molecular Pathogenesis and Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Molecular factors, like transforming growth factor beta (TGF‐β), mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase (PI3K), or cyclin‐dependent kinases (CDKs) 5 and 9, are essential modulators of atherosclerotic lesions. The novel, promising strategies for atherosclerosis treatment include therapies based on small interfering RNA (siRNA)
Jonatan Kaszubski   +3 more
wiley   +1 more source

Hepatoprotective studies on methanolic extract fractions of Lindernia ciliata and development of qualitative analytical profile for the bioactive extract

open access: yesClinical Phytoscience, 2019
Background The objective of the study is to evaluate the hepatoprotective activity of methanolic extract fractions of Lindernia ciliata (LC) and development of qualitative analytical profile of the bioactive fraction using HPLC fingerprinting analysis ...
Praneetha Pallerla   +2 more
doaj   +1 more source

LASP1, a Novel Protein in Spermatozoa and Acrosome Reaction

open access: yesMolecular Reproduction and Development, Volume 93, Issue 7, July 2026.
LASP1 is expressed in spermatozoa, binds to F‐actin, and builds up the equatorial ring structure during acrosome reaction, which is important for hyaluronan receptor surface presentation. ABSTRACT LIM and SH3 protein 1 (LASP1) is a widely expressed scaffold protein associated with actin‐rich structures. In Lasp1‐knockout mice, reproductive defects such
Alicia Bender   +8 more
wiley   +1 more source

V̇O2max$\dot V_{\rm{O_{2max}}}$‐based all‐out aerobic exercise attenuates hexosamine biosynthetic pathway activity: Metabolomic insights in mice model

open access: yesExperimental Physiology, Volume 111, Issue 7, Page 3253-3266, 1 July 2026.
Abstract Aerobic exercise enhances physiological performance by activating metabolic systems, including glucose oxidation and fat metabolism. Cellular glucose predominantly flows through glycolysis (95–98%), whereas a smaller fraction (2–5%) enters the hexosamine biosynthetic pathway (HBP), generating UDP‐N‐acetylglucosamine.
Gyumin Kang   +3 more
wiley   +1 more source

Histochemical characteristics of the vitellogenic oocytes of the bluefin tuna, Thunnus thynnus L.

open access: yesCiencias Marinas, 2002
 Very little information is available with respect to dynamic aspects of oocyte development and to yolk composition of tuna species. Since histological approaches can offer considerable information about the ovarian development of fish, and because ...
C Sarasquete   +7 more
doaj   +1 more source

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