Results 71 to 80 of about 716,794 (260)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Mitochondrial DNA. Part B. Resources, 2017 Silver pomfret fish (Stromateidae) is a family of Perciformes order. One species of this family is Pampus argenteus known as silver pomfret and lives in different parts of the Persian Gulf and Gulf of Oman. Therefore, the genetic relationship between its
Atena Sheibaninia +2 more
doaj +1 more source
Genetic characterization of Atlantic sturgeon stocking material used in Lithuania to restore the Baltic Sea population [PDF]
Acta Ichthyologica et Piscatoria, 2019 Background. Recent genetic analyses of fish remains, obtained from archaeological sites, revealed that more than 2000 years ago the Baltic Sea was inhabited by sturgeons closely related to the Atlantic sturgeon, Acipenser oxyrinchus Mitchill, 1815.
D. Butkauskas +4 more
doaj +3 more sources
TERRA and RAD51AP1 at the R&D-loop department of ALT telomeres
Molecular Cell, 2022 In this issue of Molecular Cell, Kaminski et al. and Yadav et al. demonstrate that RAD51AP1 and TERRA non-coding RNA positively regulate the alternative mechanism of telomere maintenance by promoting D-loop formation and chromatin-directed mechanisms to suppress transcription-collision events during ALT telomere synthesis.
openaire +3 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
D‐Loop Facilitates Hydride Transfer in Transhydrogenase
The FASEB Journal, 2012 Transhydrogenase (TH) is located in the mitochondrial inner membrane and maintains NADPH levels to counteract oxidative stress resulting from oxidative respiration. Enzymes in the electron transport chain work to reduce oxygen to water and pump protons (H+) into the inter‐membranous space.
Robert Ramirez +8 more
openaire +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
European Physical Journal C: Particles and Fields, 2022 We investigate the process $$B\rightarrow \bar{D}D_s \pi $$ B → D ¯ D s π via several rescattering processes. It is shown that the triangle singularity (TS) peak around the $$D^*K^*$$ D ∗ K ∗ threshold generated from the $$\chi _{c1}K^* D^*$$ χ c 1 K ∗ D
Ying-Hui Ge, Xiao-Hai Liu, Hong-Wei Ke
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A bag model calculation of the electroweaks?d? loop
Zeitschrift f�r Physik C Particles and Fields, 1991 We consider the CP-conserving electroweak transitionss→dγ. To include confinement effects below the charm scale, we perform the loop calculations within the bag model. According to the calculation, confinement effects are rather important and give amplitudes three orders of magnitude bigger than that obtained from the free quark loop, which is ∼eG F m ...
J. O. Eeg, J. �. Ruud
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source