Results 61 to 70 of about 241,206 (292)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Food fortification is an effective intervention strategy for combating micronutrient deficiencies. Vitamin A can be fortified in a wide range of food vehicles. In this research work, vitamin A in the form of palmitate (VAP) have been microencapsulated by emulsion technology intended for fortification purposes.
Tridib Kumar Goswami, Baishakhi De
openaire +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
D-OPTIMAL RESPONSE MIXTURE DESIGN MODELING OF POLYSTYRENE WASTE ADHESIVE FORMULATIONS
The importance of polystyrene in handling and transportation of fragile equipment for safe delivery cannot be under stated. However; the post-usage has raised serious concern due to adverse effects caused by the litters on environment in blocking water-ways due to its weightlessness, release of oxides of carbon and resisting decomposition among others.
Lucas Albert Jerome Hamidu +3 more
openaire +2 more sources
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Tujuan dilakukan penelitian ini adalah untuk memperoleh formulasi optimal dalam pembuatan minuman jelly lidah buaya dan daun black mulberry menggunakan program Design Expert metode Mixture D-Optimal.
Taufik, Yusman +3 more
core +1 more source
Underutilized crops such as orange-fleshed sweetpotato (OFSP) and Bambara groundnut (BNF) can help combat protein-energy malnutrition and vitamin A deficiency in sub-Saharan Africa.
Tolulope Oresanya +7 more
doaj +1 more source
BAYESIAN APPROACH TO THE D-OPTIMAL FOR MIXTURE EXPERIMENTAL DESIGN
A mixture experiment is a special case of response surface methodology in which the value of the components are proportions. In case there are constraints on the proportions, the experimental region can be not a simplex. The classical designs such as a simplex-lattice design or a simplex-centroid design, in some cases, cannot fit to the problem.
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

