Results 51 to 60 of about 241,206 (292)
Applied Food Research, 2022 The study reports the microencapsulation of ergocalciferol (vitamin D2) by emulsification technique, the experimental process parameters being chemometrically optimized by d-optimal mixture design approach followed by physico-chemical characterization of
Baishakhi De, Tridib Kumar Goswami
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Production, 2022 Abstract Paper aims Frequently, researchers try to find a better way to allocate assets in order to have maximum return and low variability in a portfolio as diverse as possible. This paper aims to apply D-Optimal Design in the context of Mixture Design and portfolio optimization to efficiently select the runs of the proposed experimental design ...
Gustavo dos Santos Leal +4 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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, 2019 Experimental runs, formulation variables, and measured responses of the D-optimal mixture experimental design.
Amal Y. Abdel-Reheem (6984296) +2 more
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, 2020 This study aimed to optimize and formulate the poorly water-soluble mefenamic acid in the self-nano emulsifying drug delivery system (SNEDDS) using D-optimal mixture design.
Syukri, Yandi +2 more
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Drug Delivery, 2022 Our study aimed to develop a self-microemulsifying drug delivery system for the poorly aqueous-soluble drug Coenzyme Q10, to improve the dissolution and the oral bioavailability.
Thapa Chhitij +11 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Comparing D-optimal designs with common mixture experimental designs for logistic regression
Chemometrics and Intelligent Laboratory Systems, 2019 Abstract Mixture experiments are used in applications where the proportion of mixing components affects a response variable, such as in studies involving chemical formulations. In many applications, the response is dichotomous or binary (e.g., pass or fail) and a concern for researchers is how to efficiently and informatively design such experiments.
Michelle V. Mancenido +3 more
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K-model ?based ?mixture ?design ?using? D-optimal and A-optimal with Qualitative Factors [PDF]
Indian Journal of Science and Technology, 2019 Objectives: To obtain a reliable approximation for the K-model in mixture experiments and design. Methods/Statistical Analysis: Here, the problem of mixture experiments, according to qualitative factors and finding A-optimal and D-optimal design for K-model is taking into account. Also, an improvement of Lee method is used to aim of this goal.
Mostafa Taheri, Chongqi Zhang
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Optimization of Chlorella milk beverage formulation using D-optimal mixture design
IOP Conference Series: Earth and Environmental Science, 2023 Abstract This study aimed to obtain the optimum formula of Chlorella milk with D-Optimal Mixture Design and to determine the consumer preference for Chlorella milk with optimum formula. This research method was divided into formulation and response design, hedonic test, response analysis, formula optimization, and verification of ...
N Y V Michelle, D Widyaningrum
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