Results 91 to 100 of about 24,603 (322)

Optimal designs for statistical analysis with Zernike polynomials [PDF]

open access: yes
n.a.
Dette, Holger   +2 more
core  

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Some Properties of Multiresponse D-Optimal Designs

open access: yesJournal of Mathematical Analysis and Applications, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Efficient conjoint choice designs in the presence of respondent heterogeneity. [PDF]

open access: yes
The authors propose a fast and efficient algorithm for constructing D-optimal conjoint choice designs for mixed logit models in the presence of respondent heterogeneity.
Goos, Peter   +2 more
core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

dCATCH—A Numerical Package for d-Variate near G-Optimal Tchakaloff Regression via Fast NNLS

open access: yesMathematics, 2020
We provide a numerical package for the computation of a d-variate near G-optimal polynomial regression design of degree m on a finite design space X ⊂ R d , by few iterations of a basic multiplicative algorithm followed by Tchakaloff-like ...
Monica Dessole   +2 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Semi-bayesian D-optimal designs and estimation procedures for mean and variance functions. [PDF]

open access: yes
Semi-Bayesian D-optimal designs for fitting mean and variance functions are derived for some prior distributions on the variance function parameters. The impact of the mean of the prior and of the uncertainty about this mean is analyzed.
Goos, Peter, Vandebroek, Martina
core  

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

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