The Conformational Panorama Of D-penicillamine: A Laser Ablation Rotational Study. [PDF]
, 2022 D-Penicillamine, a drug widely used to treat Wilson’s disease, removes copper excess from the human body by acting as a chelating agent. In the present work, we address unveiling this molecule's three-dimensional structure as a first approach to shed ...
Herreras, Diego
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The Specific Copper(II) Chelator TDMQ20 Is Efficient for the Treatment of Wilson’s Disease in Mice
Pharmaceutics, 2023 (1) Background: In patients with Wilson’s disease, the deficiency of the copper carrier ATP7B causes the accumulation of copper in the liver, brain and various other organs.
Yingshan Zhu +6 more
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Double blind controlled trial of D-penicillamine in patients with primary biliary cirrhosis.
, 1985 One hundred and eighty nine patients with primary biliary cirrhosis were entered into a double blind, placebo controlled randomised trial starting in January 1978 to assess the therapeutic value of d-penicillamine 1200 mg daily.
Tygstrup, Niels +7 more
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Pediatric Wilson Disease in Sudan: A Rare Case, Sudan Conflict and Diagnostic Challenges. [PDF]
Clin Case RepABSTRACT Wilson disease is rarely reported among African children. Wilson disease is due to a mutation in ATP7B on an autosomal recessive pattern, which causes defective copper excretion and copper accumulation in tissues such as liver and brain.
Mohammed AAA +8 more
europepmc +2 more sources
Synthesis and Characterization of Gold Chiral Nanoparticles Functionalized by a Chiral Drug
Nanomaterials, 2023 Inorganic chiral nanoparticles are attracting more and more attention due to their peculiar optical properties and potential biological applications, such as bioimaging, therapeutics, and diagnostics.
Simona Bettini +8 more
doaj +1 more source
D-Penicillamine for preventing retinopathy of prematurity in preterm infants
, 2013 Background The rate of retinopathy of prematurity (ROP) in moderately premature infants has decreased dramatically with improved care in the neonatal intensive care unit.
Kumar Manoj, Qureshi Mosarrat J.
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Arquivos de Neuro-Psiquiatria, 1969 The metabolic balances of sulfur in two cases of hepatolenticular degeneration were studied. A positive balance was found in both cases; in one patient submitted to mixed diet, the average was significantly higher than the normal mean. The administration
Horacio M. Canelas +2 more
doaj +1 more source
Late‐Onset Rheumatoid Arthritis and Air Pollution in the Multiethnic Cohort
Arthritis &Rheumatology, EarlyView.Objective To evaluate the effects of ambient air pollution on rheumatoid arthritis (RA) incidence in a racially and ethnically diverse population. Methods This analysis included 42,152 California Multiethnic Cohort participants, aged ≥65 years (>70% African American and Latino adults) who were enrolled in the Fee For Service component of Medicare (2001–
Anna H. Wu +14 more
wiley +1 more source
Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy
BMEMat, EarlyView.Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu +5 more
wiley +1 more source
Synthesis and chelating properties of substituted formyl pyridine thiosemicarbazones of potential biological activity [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 1999 The synthesis of a series of 4-(un)substituted thiosemicarbazones of 6-methyl-5-nitropyridine-2-carboxaldehyde, I (R = H, n-Bu, 4-ClC6H4, etc.), is reported by two different routes. The prepd. compds.
Hoda Hassan
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