Results 41 to 50 of about 11,635 (130)
Therapeutic Reversal of Severe Neuropsychiatric Symptoms in Wilson's Disease: A Case Report
Clinical Case Reports, Volume 14, Issue 11, November 2026.ABSTRACT Wilsons disease is an autosomal recessive genetic disorder of copper metabolism that results in copper accumulation in liver and other organs. Hepatic manifestation tends to occur earlier than the neurological manifestation. We present a case with psychiatric presentation.
Tshering Penjor +2 more
wiley +1 more source
Manic episode induced by discontinuance of D-penicillamine treatment in Wilson’s disease
Psychiatry and Clinical Psychopharmacology, 2021 Wilson’s disease (WD) is a rarely seen autosomal recessive inherited genetic disease of copper metabolism, which leads to various hepatic, orbital and neuropsychiatric disorders.
Ayse Nur Inci Kenar, Husnu Menteseoglu
doaj +1 more source
cGMP Signaling in Arterioles Revealed by FRET‐Based Real‐Time Measurement in Mice In Vivo
Acta Physiologica, Volume 242, Issue 11, November 2026.ABSTRACT cGMP evokes arteriolar vasorelaxation and is generated in smooth muscle by the soluble guanylyl cyclase (sGC) stimulated by endothelial NO. Phosphodiesterases (PDEs) degrade cGMP and may contribute in diameter regulation. We examined arteriolar cGMP levels in real‐time in vivo upon NO and acetylcholine (ACh) and effects of PDE inhibition ...
Lukas Thiele +6 more
wiley +1 more source
Statistica Neerlandica, Volume 80, Issue 4, November 2026.Abstract The Cox proportional hazards (PH) model remains the dominant approach in survival analysis, but it has two important limitations. First, it relies on the PH assumption, asserting that covariate effects act multiplicatively and remain constant over time.
Hein Putter, Liesbeth C. de Wreede
wiley +1 more source
Autopsy and Case Reports, 2021 Long term use of D-penicillamine for Wilson’s disease can be associated with many adverse reactions and systemic side effects. We report the case of a 28-year-old male patient diagnosed with Wilson’s disease presenting with a serpiginous raised ...
Swagatika Samal, Mukund Sable
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Effect of D-penicillamine in prevention of post operative pelvic adhesion formation in rat
Journal of Research in Medical Sciences, 2006 INTRODUCTION: Adhesion formation after pelvic surgery is still a major cause of several morbidities such as infertility, pain, bowel obstruction and subsequent intra-operative complications.
Ata-Allah Ghahiri +3 more
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Biometrical Journal, Volume 68, Issue 5, October 2026.ABSTRACT The Cox proportional hazards model is often used to analyze data from randomized controlled trials (RCTs) with time‐to‐event outcomes. Random survival forest (RSF) is a machine‐learning algorithm known for its high predictive performance. We conduct a comprehensive neutral comparison study to compare the performance of Cox regression and RSF ...
Ricarda Graf, Susan Todd, M. Fazil Baksh
wiley +1 more source
Efficient near‐infrared light‐emitting diodes via enlarging grains of tin‐based perovskites
InfoMat, Volume 8, Issue 10, October 2026.In this work, penicillamine molecules are introduced into Sn‐based perovskites to slow crystallization, yielding large‐grain films with reduced grain boundaries and passivated defects. The resulting perovskite light‐emitting diodes achieve a maximum external quantum efficiency of 17.5% at 894 nm and an operational half‐lifetime of 0.95 h under current ...
Piaoyang Shen +4 more
wiley +1 more source
Iron and Other Metal Ions in Human Health and Disease
MedComm, Volume 7, Issue 10, October 2026.Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
Effect of D-penicillamine on Vitamin B6 Activation of Aspartate Aminotransferase in Synaptosomes of the Developing Brain [PDF]
Journal of Sciences, Islamic Republic of Iran, 1989 The activity of aspartate aminotransferase a vitamin B6 containing enzyme was measured in the laysed synaptosomes prepared from rat brain, during development. Administration of vitamin B6 increased the enzyme activity throughout development.
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