Results 51 to 60 of about 12,790 (151)

Intracerebroventricular administration of the (1→6)-β-d-glucan (lasiodiplodan) in male rats prevents d-penicillamine-induced behavioral alterations and lipoperoxidation in the cortex

Pharmaceutical Biology, 2017
Context: Lasiodiplodan, an exocellular (1→6)-β-d-glucan of molecular weight >1.4 × 106 Da produced by MMPI strain of Lasiodiplodia theobromae (Pat.) Griffon & Maubl.
Carlos Ricardo Maneck Malfatti, Fabio Seidel dos Santos, Jéssica Wouk, Luiz Augusto da Silva, Renan Garcia Michel, André Luiz Snak, Tiago Czervinski, Mário A. Alves da Cunha, Aneli M. Barbosa, Robert F. H. Dekker   +9 more
doaj   +1 more source

Manifestation of morphea in a patient with myasthenia gravis under therapy with zilucoplan

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Phoebe Wellmann, Jana Zschüntzsch, Michael P. Schön, Rotraut Mössner   +3 more
wiley   +1 more source

Methanobactin rapidly facilitates biliary copper excretion in a Wilson disease rat model visualised by 64Cu PET/MRI

British Journal of Pharmacology, Volume 183, Issue 2, Page 268-279, January 2026.
Background and Purpose Methanobactins are peptides with high copper affinity and potential to treat Wilson disease. We examined how two methanobactins (ARBM101 and MB‐OB3b) affected copper handling in the LPP Atp7b−/− Wilson disease rat model, compared to penicillamine or saline, by 64Cu positron emission tomography/magnetic resonance imaging ...
Emilie Munk Lynderup, Mikkel Holm Vendelbo, Frederik Teicher Kirk, Karina Højrup Vase, Aage Kristian Olsen Alstrup, Tamara Rieder, Alan A. DiSpirito, Jeremy D. Semrau, Tea Lund Laursen, Peter Ott, Hans Zischka, Thomas Damgaard Sandahl   +11 more
wiley   +1 more source

Sensing of Copper(II) by Immobilized Ligands: Comparison of Electrochemical and Surface Plasmon Resonance Transduction

Proceedings, 2019
Two sensors for the detection of the metal ion Cu(II), based on the same sensing layer, are compared. They rely on different transduction methods, i.e., electrochemistry and surface plasmon resonance (SPR).
Maria Pesavento, Nunzio Cennamo, Raffaela Biesuz, Antonella Profumo, Daniele Merli   +4 more
doaj   +1 more source

Myasthenia Gravis Outcomes After Use of Statins and Other Contraindicated Treatments: Results From the French National Insurance Database

European Journal of Neurology, Volume 33, Issue 1, January 2026.
In this real‐world study among 14,459 adults with MG, exposure to any contraindicated treatment was not significantly associated with risk of ICU admission for MG but was associated with significantly higher risk of death. In contrast, statins were associated with a greater risk of ICU admission but a lower risk of death.
Guilhem Solé, Jean Philippe Camdessanché, Shahram Attarian, Mariana Ciumas, Cécile Blein, Benjamin Grenier, Eléonore Herquelot, Andoni Echaniz‐Laguna   +7 more
wiley   +1 more source

Impact of FSH‐Induced Ovarian Stimulation on Oocyte Recovery and In Vitro Embryo Production in the Red Sindhi Cows

Reproduction in Domestic Animals, Volume 61, Issue 1, January 2026.
ABSTRACT Follicle‐stimulating hormone (FSH) plays an important role in regulating reproductive events, particularly follicular development and oocyte competence acquisition. Some studies using FSH protocols in zebu cattle were performed, but data regarding its application in the Red Sindhi breed are scarce and therefore warranted. In this context, this
Ivo Pivato, George Henrique Lima Martins, Lucas Costa de Faria, Heidi Christina Bessler, Carlos Frederico Martins   +4 more
wiley   +1 more source

Effect of D-penicillamine on Vitamin B6 Activation of Aspartate Aminotransferase in Synaptosomes of the Developing Brain [PDF]

Journal of Sciences, Islamic Republic of Iran, 1989
The activity of aspartate aminotransferase a vitamin B6 containing enzyme was measured in the laysed synaptosomes prepared from rat brain, during development. Administration of vitamin B6 increased the enzyme activity throughout development.
doaj  

Modality of treatment and potential outcome of Wilson disease in Taiwan: A population-based longitudinal study

Journal of the Formosan Medical Association, 2018
Background/Purpose: This study aimed to investigate the epidemiology, the preference of medication, and the potential outcome of Wilson disease in Taiwan.
Chi-San Tai, Jia-Feng Wu, Huey-Ling Chen, Hong-Yuan Hsu, Mei-Hwei Chang, Yen-Hsuan Ni   +5 more
doaj   +1 more source

Plasma Glial Fibrillary Acidic Protein Correlates With Brain Metal Burden in Wilson's Disease

Annals of Clinical and Translational Neurology, Volume 12, Issue 12, Page 2433-2445, December 2025.
ABSTRACT Objective Neuroinflammation driven by extracellular copper contributes to neuronal damage in Wilson's disease (WD). This study investigated the relationship between brain metal burden and peripheral neuroinflammation markers in WD. Methods We conducted a cross‐sectional study involving 89 participants, including patients with WD (n = 63 ...
Sung‐Pin Fan, Ya‐Fang Chen, Cheng‐Hsuan Li, Yih‐Chih Kuo, Ni‐Chung Lee, Yin‐Hsiu Chien, Wuh‐Liang Hwu, Tai‐Chung Tseng, Tung‐Hung Su, Chien‐Ting Hsu, Huey‐Ling Chen, Chin‐Hsien Lin, Yen‐Hsuan Ni   +12 more
wiley   +1 more source

Exploring Nasal Structural‐Microbial Interactions in Multiple Sclerosis‐Associated Olfactory Impairment

Annals of Clinical and Translational Neurology, Volume 12, Issue 12, Page 2546-2557, December 2025.
ABSTRACT Background Olfactory dysfunction is frequently observed in patients with multiple sclerosis (MS); however, its underlying mechanisms remain poorly understood. To date, no studies have directly examined the nasal mucosal microbiota in MS. This study aimed to explore potential relationships among olfactory function, nasal microbiota composition,
Zidan Gao, Zhuoma Danzhen, Yao Li, Junyu Zhu, Lan Chu, Zhang Yang   +5 more
wiley   +1 more source