Results 131 to 140 of about 15,108,845 (313)

Affinity Peptides With pH Sensitivity for the Enrichment of CD38+ Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The selective enrichment of cell populations based on surface markers is critical for the advancement of gene and cell therapies. Current antibody‐based cell isolation methods, such as fluorescence‐ and magnetic‐activated cell sorting (FACS and MACS), offer high specificity but are limited by scalability, cost, and potential adverse effects on
Gabrielle Rusch, Mickael Meyer, I. Mohamed Irfan, Carson Huber, Joseph Burclaff, Scott T. Magness, Stefano Menegatti, Michael Daniele   +7 more
wiley   +1 more source

(3R,4R,5R)-5-(Acetamidomethyl)-N-benzyl-3,4-dihydroxytetrahydrofuran-3-carboxamide

Acta Crystallographica Section E, 2010
X-ray crystallographic analysis with Cu Kα radiation established the relative configurations of the stereogenic centers in the title compound, C15H20N2O5, and clarified mechanistic ambiguities in the synthesis.
Michela I. Simone, Alison A. Edwards, Andrew R. Cowley, George W. J. Fleet, David J. Watkin   +4 more
doaj   +1 more source

Nicotinamide Reverses the Warburg Effect in CHO Cell Culture

Biotechnology and Bioengineering, EarlyView.
Abstract The Warburg effect, the preferential conversion of glucose‐derived pyruvat to lactate despite available oxygen, is a key feature of Chinese hamster ovary (CHO) cell culture. Lactate accumulation in recombinant protein‐producing cell culture is an inefficient usage of glucose, as well as being deleterious to cells.
James Morrissey, Ayca Cankorur‐Cetinkaya, Luigi Grassi, Annie J. Harwood‐Stamper, Jonathan Welsh, Ryte Poskute, Kasia Kozakowska‐McDonnell, Cleo Kontoravdi   +7 more
wiley   +1 more source

Improved Synthesis of β-D-6-Methylpurine Riboside and Antitumor Effects of the β-D- and α-D-Anomers

Molecules, 2005
6-Methylpurine-β-D-riboside (β-D-MPR) has been synthesized by coupling6-methylpurine and 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribose using conditions that producethe β-D-anomer exclusively.
J. Sufrin, R. Bernacki, A. Spiess, P. Pera, C. Marasco   +4 more
doaj   +1 more source

A spectrophotometric study of the behavior of carbohydrates in seventy-nine per cent sulfuric acid [PDF]

, 1949
The spectral characteristics of solutions of eighteen representative monosaccharides in 79 per cent sulfuric acid have been determined for solutions maintained for 2 hours at 25° and 15 minutes at 100°.
Ikawa, Miyoshi, Niemann, Carl
core  

Defect engineering for highly efficient and stable perovskite top cells for Si tandems

Bulletin of the Korean Chemical Society, EarlyView.
Defect passivation in wide‐bandgap perovskites is essential for enabling high‐efficiency and stable perovskite/Si tandem solar cells. Bulk, surface, and buried‐interface passivation strategies focus on suppressing nonradiative recombination, ion migration, and halide segregation, thereby clarifying critical design principles for next‐generation tandem ...
Ju Yeong Hong, Young Seon Yoon, Jin Young Kim   +2 more
wiley   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

Preparative scale enzymatic synthesis of D-sedoheptulose-7-phosphate from β-hydroxypyruvate and D-ribose-5-phosphate [PDF]

, 2009
International audienceAn enzymatic method for ready access to D-sedoheptulose-7-phosphate on a preparative scale was developed, based on the irreversible transketolase-catalyzed reaction: β-hydroxypyruvate + D-ribose-5- phosphate → D-sedoheptulose-7 ...
Charmantray, Franck, Hecquet, Laurence, Hélaine, Virgil, Legeret, Bertrand   +3 more
core   +1 more source

Engineering Bisubstrates to Target m6Am RNA Methyltransferases: Synthesis and Computational Studies

Chemistry – A European Journal, EarlyView.
Use of the convertible nucleoside approach to synthesize m6Am RNA methyltransferase bisubstrates. This methodology allows for the introduction of modifications on the SAM analog moiety and the RNA substrate part, including the introduction of a cap analog by click chemistry.
Yoann Colas, Laurent Le Corre, Mélanie Ethève‐Quelquejeu, Emmanuelle Braud   +3 more
wiley   +1 more source