Results 121 to 130 of about 15,108,845 (313)

K:D-Rib: cancer cell proliferation inibitor and DNAzyme folding promoter

open access: yesJournal of Biological Research, 2014
We report the effects of K:D-Rib, a D-ribose and KHCO3 water solution on HTB-126 human cancer cell line proliferation and the preliminary ultraviolet-visible (UV-VIS) measures of DNAzyme as biosensor of extracellular K+ concentration. On the one hand, we
Luca Bruni, Simonetta Croci
doaj   +1 more source

Genome sequence of Ensifer arboris strain LMG 14919T: a microsymbiont of the legume Prosopis chilensis growing in Kosti, Sudan [PDF]

open access: yes, 2014
Ensifer arboris LMG 14919T is an aerobic, motile, Gram-negative, non-spore-forming rod that can exist as a soil saprophyte or as a legume microsymbiont of several species of legume trees.
Bräu, Lambert   +16 more
core   +1 more source

Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling

open access: yesAngewandte Chemie International Edition, EarlyView.
Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl   +1 more
wiley   +1 more source

Convenient Synthesis of 1,4-Dideoxy-1,4-imino-D-ribitol from D-Ribose

open access: yesJournal of Chemistry, 2013
This paper describes a convenient synthesis of 1,4-dideoxy-1,4-imino-D-ribitol (DRB) from D-ribose. L-Lyxonolactone, a key intermediate in this synthesis, was prepared by base-promoted hydrolysis of a 5-chlorinated D-ribonolactone derivative with ...
Makoto Oba   +4 more
doaj   +1 more source

D-ribose-glycation of insulin prevents amyloid aggregation and produces cytotoxic adducts.

open access: yesBiochimica et Biophysica Acta, 2016
Insulin is a key hormone regulating glucose homeostasis, intimately associated with glycemia and is exposed to glycation by glucose, reducing sugars and other highly reactive carbonyls, particularly in diabetes.
Clara Iannuzzi   +8 more
semanticscholar   +1 more source

Complete genome sequence of Planctomyces limnophilus type strain (Mü 290). [PDF]

open access: yes, 2010
Planctomyces limnophilus Hirsch and Müller 1986 belongs to the order Planctomycetales, which differs from other bacterial taxa by several distinctive features such as internal cell compartmentalization, multiplication by forming buds directly from the ...
Bristow, James   +31 more
core   +1 more source

How enzyme economy shapes metabolic fluxes

open access: yes, 2014
Metabolic fluxes are governed by physical and economic principles. Stationarity constrains them to a subspace in flux space and thermodynamics makes them lead from higher to lower chemical potentials.
Liebermeister, Wolfram
core  

Hepatotoxicity of Nonesterified Fatty Acids to Dairy Cows: Pathophysiological Mechanisms and Prospective Solutions

open access: yesAnimal Research and One Health, EarlyView.
Unregulated inflammation increases non‐esterified fatty acids (NEFAs), and triggers multi‐pathway hepatocyte damage including oxidative stress, mitochondrial dysfunction, and metabolic disorders in dairy cows. ABSTRACT Circulating concentrations of nonesterified fatty acids (NEFAs) are elevated due to lipid mobilization from adipose tissue in ...
Siqing Mao   +12 more
wiley   +1 more source

Bacterial Pigments as Potential Antitumor Agents Against Gastrointestinal Cancers: A Comprehensive Systematic Review

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara   +5 more
wiley   +1 more source

Prebiotic synthesis of 2-deoxy-d-ribose from interstellar building blocks promoted by amino esters or amino nitriles.

open access: yesChemical Communications, 2017
Understanding the prebiotic genesis of 2-deoxy-d-ribose, which forms the backbone of DNA, is of crucial importance to unravelling the origins of life, yet remains open to debate.
A. Steer   +3 more
semanticscholar   +1 more source

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