Results 31 to 40 of about 15,108,845 (313)

Potential use of ubiquinol and d-ribose in patients with heart failure with preserved ejection fraction. [PDF]

open access: yesAnn Med Surg (Lond), 2020
Highlights • Manuscript Highlights.• HFpEF is associated with reduced ATP production in the myocardium.• Ubiquinol and d-ribose both contribute to the generation of myocardial ATP.• Both ubiquinol and d-ribose are being studied as supplemental treatments
Pierce JD   +6 more
europepmc   +2 more sources

Hormonal changes and redox imbalance in nicotine-induced testicular toxicity: the mitigating influence of D-ribose l-cysteine

open access: yesJournal of Basic and Applied Zoology, 2020
Background The effects of D-ribose l-cysteine on nicotine-induced testicular toxicity in male Wistar rats were examined in this study. Twenty healthy adult male Wistar rats with an average weight of 200 g were grouped as normal control, nicotine (2 mg/kg)
Victor O. Ukwenya   +3 more
doaj   +1 more source

Protective Effect and Mechanism of D-ribose on Doxorubicin-induced Cardiotoxicity

open access: yesShipin gongye ke-ji, 2022
Objective: To study the protective effect and mechanism of D-ribose on Doxorubicin (DOX)-induced cardiotoxicity in mice. Methods: Eight-week-old male ICR mice were randomly divided into normal group (Con), model (DOX) group, D-ribose low-dose group (LDR)
Aiai XIAO   +3 more
doaj   +1 more source

Lysosomal regulation of extracellular vesicle excretion during d-ribose-induced NLRP3 inflammasome activation in podocytes. [PDF]

open access: yesBiochim Biophys Acta Mol Cell Res, 2019
The NLRP3 inflammasome is activated in the cytoplasm of cells and its products such as IL-1β are exported through a non-classical ER-Golgi pathway. Several mechanistically distinct models including exocytosis of secretory lysosomes, microvesicles (MVs ...
Hong J   +7 more
europepmc   +2 more sources

Effects of hydroxyapatite (0001) Ca2+/Mg2+ substitution on adsorbed D-ribose ring puckering [PDF]

open access: yes, 2016
Advanced Molecular Dynamics (MD) simulation protocols have been used to assess the ring puckering of cyclic D-ribose when the sugar is adsorbed on the most stable (0001) facet of calcium hydroxyapatite (HAp).
Alemán Llansó, Carlos   +5 more
core   +2 more sources

d-Ribose Catabolism in Archaea: Discovery of a Novel Oxidative Pathway in Haloarcula Species. [PDF]

open access: yesJ Bacteriol, 2020
The utilization and degradation of d-ribose in archaea, the third domain of life, have not been analyzed so far. We show that Haloarcula species utilize d-ribose, which is degraded to α-ketoglutarate via a novel oxidative pathway.
Johnsen U   +6 more
europepmc   +2 more sources

Mycobacterium tuberculosis Decaprenylphosphoryl-β-D-ribose Oxidase inhibitors: expeditious reconstruction of sub-optimal hits into a series with potent in vivo activity.

open access: yesJournal of Medicinal Chemistry, 2020
Decaprenylphosphoryl-β-D-ribose 2'-epimerase (DprE1) is an essential enzyme in Mycobacterium tuberculosis and has recently been studied as a potential drug target, with inhibitors progressing to clinical studies.
Jennifer A Borthwick   +13 more
semanticscholar   +1 more source

Inhibition of Cell Proliferation by D-Ribose and Deoxy-D-ribose

open access: yesExperimental Biology and Medicine, 1985
D-Ribose and deoxy-D-ribose inhibited DNA, RNA, and protein synthesis in a wide variety of cells (dividing and nondividing, normal and neoplastic, freely floating and substrate adhering, human and murine) at concentrations at which other monosaccharides have little or no effect.
M, Marini, G, Zunica, C, Franceschi
openaire   +2 more sources

Evaluation of the anti-ischemic effects of D-ribose during dobutamine stress echocardiography: a pilot study

open access: yesCardiovascular Ultrasound, 2009
D-Ribose, a pentose sugar, has shown to improve myocardial high-energy phosphate stores depleted by ischemia. This study investigated the ability of D-Ribose with low dose dobutamine to improve the contractile response of viable myocardium to dobutamine ...
Gradus-Pizlo Irmina   +6 more
doaj   +1 more source

An immunohistochemical analysis to validate the rationale behind the enhanced immunogenicity of D-ribosylated low density lipo-protein. [PDF]

open access: yesPLoS ONE, 2014
Advanced glycation end products (AGEs) are thought to contribute to the abnormal lipoprotein profiles and increased risk of cardiovascular disease in patients with diabetes and renal failure.
Firoz Akhter   +3 more
doaj   +1 more source

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