Results 41 to 50 of about 15,108,845 (313)

2-Deoxy-D-ribose-5-phosphate aldolase (DERA): applications and modifications. [PDF]

open access: yesAppl Microbiol Biotechnol, 2018
2-Deoxy-d-ribose-5-phosphate aldolase (DERA) is a class I aldolase that offers access to several building blocks for organic synthesis. It catalyzes the stereoselective C–C bond formation between acetaldehyde and numerous other aldehydes.
Haridas M, Abdelraheem EMM, Hanefeld U.
europepmc   +2 more sources

D-ribose induces nephropathy through RAGE-dependent NF-κB inflammation. [PDF]

open access: yesArch Pharm Res, 2018
Recently, aberrantly high levels of d-ribose have been discovered in type II diabetic patients. d-ribose glycates proteins more rapidly than d-glucose, resulting in the production of advanced glycation end products (AGEs). Accumulations of these products
Hong J, Wang X, Zhang N, Fu H, Li W.
europepmc   +2 more sources

Deoxy-sugar releasing biodegradable hydrogels promote angiogenesis and stimulate wound healing [PDF]

open access: yes, 2017
Vascular endothelial growth factor (VEGF) stimulates endothelial cells to migrate, proliferate and form new blood vessels. However direct delivery of VEGF has not become clinically adopted as a means of stimulating blood vessel formation and wound ...
Badylak   +48 more
core   +1 more source

Daily supplementation of D-ribose shows no therapeutic benefits in the MHC-I transgenic mouse model of inflammatory myositis. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Current treatments for idiopathic inflammatory myopathies (collectively called myositis) focus on the suppression of an autoimmune inflammatory response within the skeletal muscle.
William Coley   +4 more
doaj   +1 more source

d-Ribose contributes to the glycation of serum protein.

open access: yesBiochimica et Biophysica Acta - Molecular Basis of Disease, 2019
d-Ribose is active in glycation and rapidly produces advanced glycation end products, leading to cell death and to cognitive impairment in mice. Glycated serum protein (GSP) is a relatively short-term biomarker for glycemic control in diabetes mellitus ...
Yao Chen   +6 more
semanticscholar   +1 more source

Prolonged glycation of hen egg white lysozyme generates non amyloidal structures. [PDF]

open access: yesPLoS ONE, 2013
Glycation causes severe damage to protein structure that could lead to amyloid formation in special cases. Here in this report, we have shown for the first time that hen egg white lysozyme (HEWL) does not undergo amyloid formation even after prolonged ...
Sudeshna Ghosh   +5 more
doaj   +1 more source

Butremycin, the 3-Hydroxyl Derivative of Ikarugamycin and a Protonated Aromatic Tautomer of 5′-Methylthioinosine from a Ghanaian Micromonospora sp. K310 [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
Anil Sazak   +10 more
core   +1 more source

Ribose 5-phosphate isomerase B knockdown compromises Trypanosoma brucei bloodstream form infectivity. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2015
Ribose 5-phosphate isomerase is an enzyme involved in the non-oxidative branch of the pentose phosphate pathway, and catalyzes the inter-conversion of D-ribose 5-phosphate and D-ribulose 5-phosphate.
Inês Loureiro   +7 more
doaj   +1 more source

Anti-atherogenic properties associated with the antioxidant activity from the hydrophilic extracts of Halimeda incrassata (Chlorophyta, Bryopsidales) [PDF]

open access: yes, 2017
Seaweeds are a source of natural antioxidants having potential application in oxidative stress and associated diseases. In this work, anti-atherogenic properties associated with the antioxidant activity from the hydrophilic extracts of Halimeda ...
Claudina, Zaldívar-Munoz   +8 more
core   +1 more source

Synthesis and bioactivity of a conjugate composed of green tea catechins and hyaluronic acid [PDF]

open access: yes, 2015
(-)-Epigallocatechin-3-gallate (EGCG) is a green tea polyphenol that has several biological activities, including anti-cancer activity and anti-inflammation.
Chung, Joo Eun   +7 more
core   +1 more source

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