Tailoring the natural rare sugars D-tagatose and L-sorbose to produce novel functional carbohydrates [PDF]
npj Science of FoodThis multidisciplinary study details the biosynthesis of novel non-digestible oligosaccharides derived from rare sugars, achieved through transfructosylation of D-tagatose and L-sorbose by levansucrase from Bacillus subtilis CECT 39 (SacB).
Oswaldo Hernandez-Hernandez +11 more
doaj +2 more sources
Biocatalytic Synthesis of D-Allulose Using Novel D-Tagatose 3-Epimerase From Christensenella minuta [PDF]
Frontiers in Chemistry, 2020 D-allulose, which is one of the important rare sugars, has gained significant attention in the food and pharmaceutical industries as a potential alternative to sucrose and fructose.
Yang Wang +8 more
doaj +2 more sources
Biochemical analysis and the preliminary crystallographic characterization of d-tagatose 3-epimerase from Rhodobacter sphaeroides [PDF]
Microbial Cell Factories, 2017 Background d-Tagatose 3-epimerase epimerizes d-fructose to yield d-psicose, which is a rare sugar that exists in small quantities in nature and is difficult to synthesize chemically.
Zhengliang Qi +7 more
doaj +2 more sources
D‑Tagatose inhibits the growth and biofilm formation of Streptococcus mutans. [PDF]
Mol Med Rep, 2018 Dental caries is an important global health concern and Streptococcus mutans has been established as a major cariogenic bacterial species. Reports indicate that a rare sugar, D‑tagatose, is not easily catabolized by pathogenic bacteria. In the present study, the inhibitory effects of D‑tagatose on the growth and biofilm formation of S. mutans GS‑5 were
Hasibul K +10 more
europepmc +4 more sources
Biochemical properties of L-arabinose isomerase from Clostridium hylemonae to produce D-tagatose as a functional sweetener. [PDF]
PLoS ONE, 2018 d-Tagatose has gained substantial interest due to its potential functionalities as a sucrose substitute. In this study, the gene araA, encoding l-arabinose isomerase (l-AI) from Clostridium hylemonae (DSM 15053), was cloned and expressed in Escherichia ...
Tien-Kieu Nguyen +4 more
doaj +2 more sources
The Effect of D-Tagatose on Fructose Absorption in a Rat Model. [PDF]
J Dev Drugs, 2013 D-tagatose is in development as a medication for the treatment of type 2 diabetes. The effect of oral D-tagatose on the absorption of D-fructose was assessed when co-administered in this study. In the pilot study, male Sprague-Dawley rats were fed C14 labeled fructose and glucose concomitantly to establish dose levels for the treatment group of rats ...
Williams J, Spitnale M, Lodder R.
europepmc +4 more sources
Engineering the l-Arabinose Isomerase from Enterococcus Faecium for d-Tagatose Synthesis [PDF]
Molecules, 2017 l-Arabinose isomerase (EC 5.3.1.4) (l-AI) from Enterococcus faecium DBFIQ E36 was overproduced in Escherichia coli by designing a codon-optimized synthetic araA gene. Using this optimized gene, two N- and C-terminal His-tagged-l-AI proteins were produced.
Marylane de Sousa +5 more
doaj +2 more sources
Regulation of the tagatose catabolic gene cluster and development of a tagatose-inducible expression system in the probiotic Escherichia coli Nissle 1917 [PDF]
Microbial Cell FactoriesBackground The probiotic Escherichia coli Nissle 1917 (EcN) is a promising microbial chassis for therapeutic and industrial applications. However, its broad utility is limited by a lack of reliable inducible gene expression systems that precisely control
Keunha Park +6 more
doaj +2 more sources
Advances in Biological Production of D-Tagatose: A Comprehensive Overview
FermentationD-tagatose is a rare, naturally occurring low-calorie hexose, with a sweetness of 92% sucrose but only 1/3 of the calories. It has beneficial functions in lowering blood sugar, controlling obesity, preventing dental caries, and improving intestinal flora.
Hailin Zhang +5 more
doaj +2 more sources
Research Progress on Physiological Activity and Biosynthesis of D-Tagatose(D-塔格糖的生理活性及生物合成研究进展) [PDF]
Shipin kexue jishu xuebao, 2023 D-Tagatose is an important rare ketohexose. Its sweetness is 92% of sucrose, and its calories are only one third of sucrose. D-Tagatose was approved as a new raw material for safe food by the America's Food and Drug Administration and China's Health and ...
LI Zijie(李子杰) +4 more
doaj +1 more source