Results 41 to 50 of about 111,730 (260)

Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell‐Type‐Specific TGFβ Modulators

open access: yesAdvanced Science, EarlyView.
The mammalian TGFβ interacts with ubiquitously expressed TGFBR1 and TGFBR2, and current TGFβ‐targeting agents are non‐cell‐selective. The cooperative interaction of the modular parasite TGFβ antagonist with multiple host (co‐)receptors empowers the design of TGM chimeras and bispecific antibodies that activate or inhibit TGFβ signaling in a cell ...
Maarten van Dinther   +13 more
wiley   +1 more source

Where post-Newtonian and numerical-relativity waveforms meet [PDF]

open access: yes, 2007
We analyze numerical-relativity (NR) waveforms that cover nine orbits (18 gravitational-wave cycles) before merger of an equal-mass system with low eccentricity, with numerical uncertainties of 0.25 radians in the phase and less than 2% in the amplitude;
A. Buonanno   +10 more
core   +3 more sources

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

open access: yesAdvanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao   +10 more
wiley   +1 more source

A Paediatric Perspective: Opportunities and Challenges in Emergency Department Antimicrobial Stewardship

open access: yesAntibiotics
The Emergency Department (ED) represents an ideal location for antimicrobial stewardship (AMS) intervention, given the large volume of antibiotics seen prescribed to a wide variety of patients.
Karen N. McCarthy   +2 more
doaj   +1 more source

The Development of E-Commerce and Consumer Attitudes – A Comparative Analysis of Poland, Ukraine and Belarus

open access: yesFolia Oeconomica Stetinensia, 2020
Research background: Motivation for this paper is the rapid development of the electronic commerce sector and its increasing role as a sales channel. The level of e-commerce development is spatially diverse, both across continents and countries. As such,
Gregor Bogdan, Kalińska-Kula Magdalena
doaj   +1 more source

The Economic Influence on Consumers Buying Behavior in Islamic Countries: Evidence from the COVID-19 Economic Crisis

open access: yesECONOMICS, 2021
The Covid-19 pandemic has ushered in a new age in the world. We are still grappling with the implications in various areas of our everyday lives. The impulsive buying habits of consumers, the supply chain, and the whole industry are not exceptions ...
Mukit Mohammad Mushfiqul Haque   +3 more
doaj   +1 more source

Majority‐Voting Overlapping Method for Error Correction in DNA Data Storage

open access: yesAdvanced Intelligent Discovery, EarlyView.
We propose an overlapping‐based majority‐voting method for DNA data storage error correction. By aligning multiple reads and choosing the most frequent base per position, it suppresses substitution errors without prior models. Validated on synthetic and real sequencing data, it achieves high‐fidelity, scalable, and cost‐effective reconstruction ...
Thi Bich Ngoc Nguyen   +5 more
wiley   +1 more source

On cofinitely (D12)-modules

open access: yesMiskolc Mathematical Notes
In this paper, concepts of (cofinitely) (D12∗) ⊕δM (D12∗)AMBMf:B→MAker(f)≪δBM (D12∗)AMBMf:B→MAker(f)≪δBδ (D12∗)
Figen Eryılmaz
doaj   +1 more source

Digital Divide and the Use of Digital Public Services During the COVID-19 Pandemic

open access: yesNaše Gospodarstvo, 2023
The COVID-19 pandemic enhanced digital transformation. With the spread of the pandemic and the introduction of epidemiological measures, citizens were enforced to use the Internet to an increased extent.
Slijepčević Sunčana
doaj   +1 more source

Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues

open access: yesAdvanced NanoBiomed Research, EarlyView.
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt   +4 more
wiley   +1 more source

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