Gastrointestinal Tract Involvement of Gorham's Disease with Expression of D2-40 in Duodenum. [PDF]
We present a case of a 13-year-old boy with Gorham's disease involving the thoracic and lumbar spine, femur, and gastrointestinal (GI) tract, which was complicated by recurrent chylothorax and GI bleeding. The presenting symptoms were intermittent abdominal pain, back pain, and melena.
Choi BS +6 more
europepmc +4 more sources
Diagnostic value of D2-40 immunostaining for malignant mesothelioma: a meta-analysis. [PDF]
Malignant mesothelioma (MM) has become a global disease burden for its rising incidence and invariable fatality. D2-40 has been widely used as an immunostaining marker of diagnosing MM, while its diagnostic value has not yet been evaluated. Our study aimed to assess the overall accuracy of D2-40 immunostaining for diagnosing MM through a meta-analysis.
He C, Wang B, Wan C, Yang T, Shen Y.
europepmc +4 more sources
D2-40/podoplanin expression in the human placenta. [PDF]
Placental tissue expresses many lymphatic markers. The current study was undertaken to examine if D2-40/podoplanin, a lymphatic endothelial marker, was expressed in the human placenta, and how it is altered developmentally and pathologically. We examined D2-40/podoplanin and VEGFR-3 expressions in placentas from normotensive pregnancies at different ...
Wang Y +5 more
europepmc +4 more sources
MRI Radiomics-Based Prediction of Occult Sentinel Lymph Node Metastasis and D2-40 Expression in Breast Cancer [PDF]
Introduction Patients with Magnetic Resonance Imaging (MRI) axillary lymph node (ALN) negative in breast cancer may still have occult sentinel lymph node (SLN) metastases, which can influence clinical treatment strategies.
Mingming Chen MB +5 more
doaj +2 more sources
Plexiform Fibromyxoma with MALAT1–GLI1 Fusion with Limited Myxoid Stroma, Aberrant KIT Expression, and Diffuse D2-40 Expression: A Case Report [PDF]
Background and Clinical Significance: Plexiform fibromyxoma (PFM) is a rare benign gastric mesenchymal neoplasm characterized by multinodular plexiform growth of bland spindle cells in a myxoid or fibromyxoid stroma. We report a case of the cellular form
Kotaro Watanabe +11 more
doaj +2 more sources
Enhanced detection of lymphovascular invasion in small rectal neuroendocrine tumors using D2‐40 and Elastica van Gieson immunohistochemical analysis [PDF]
Rectal neuroendocrine tumor (RNET) lymphovascular invasion (LVI) is regarded as an important predictor of nodal metastasis after endoscopic resection (ER).
Yoshiyasu Kitagawa +12 more
doaj +2 more sources
Periacinar Retraction Clefting and D2-40 Expression in Prostatic Adenocarcinoma [PDF]
Retraction clefting is known to appear in various types of tumors, but it has only recently been recognized as a specific histological phenomenon. Previously, it was considered merely a laboratory procedure artifact, but lately, there have been some assumptions that peritumoral retractions actually represent lymphatic spaces.
Ulamec, Monika +5 more
openaire +6 more sources
Expression of Claudin-4 and D2-40 and their significance in prostatic adenocarcinoma
ABSTRACT Background: Claudins are a clan of proteins that are the most important component of tight junctions. The claudin-4 expression has been linked to tumour cell invasion and progression in a variety of primary malignancies.
Hardik, Kabra +5 more
openaire +2 more sources
A Study of D2-40 Immunohistochemical Expression in Colorectal Carcinomas [PDF]
Background: Colorectal cancer is one of the most common cancers. Factors affecting survival include nodal positivity, lymphovascular invasion (LVI) and lymphangiogenesis (role in metastasis). Most endothelial markers stain lymphatics and blood vessels without discrimination. Recent marker D2-40 is specific for lymphatic endothelium.
Sarvek Bajaj +2 more
openaire +1 more source
Background: The presence of lymph-vascular space invasion is a powerful predictor of lymph node metastasis. However, most studies do not distinguish lymph vessel invasion (LVI) and blood vessel invasion (BVI). The aim of this study was to distinguish the
Juan Xu +4 more
doaj +1 more source

