Results 1 to 10 of about 3,631,784 (211)

Serologic characterization of anti-protamine/heparin and anti-PF4/heparin antibodies

Blood Advances, 2017
: Anti-protamine (PRT)/heparin antibodies are a newly described class of heparin-dependent antibodies occurring in patients exposed to PRT and heparin during cardiac surgery.
Grace M. Lee, Manali Joglekar, Maragatha Kuchibhatla, Sanjay Khandelwal, Rui Qi, Lubica Rauova, Gowthami M. Arepally   +6 more
doaj   +1 more source

Bispecific antibodies and their use in applied research

Veterinary World, 2012
Bispecific antibodies (BsAb) can, by virtue of combining two binding specificities, improve the selectivity and efficacy of antibody-based treatment of human disease.
Harshit Verma, Durairajan Ramachandran, Ashabaree Samal   +2 more
doaj   +1 more source

Constitutive overexpression of a novel 21 kDa protein by Hodgkin Lymphoma and Aggressive Non-Hodgkin Lymphomas

Molecular Cancer, 2008
Background CD30, a 120 kDa surface phosphorylated protein is a member of tumour necrosis/nerve growth factor receptor (TNF/NGFR) family and constitutively expressed by Hodgkin and Reed-Sternberg (HRS) cells of Hodgkin lymphoma (HL) and the neoplastic ...
Gascoyne Randy D, Skinnider Brian, Cohn Jason B, Fadlelmola Faisal M, Zhou Minglong, Banerjee Diponkar   +5 more
doaj   +1 more source

Development of ELISA test for the quality control of Pseudomonas aeruginosa recombinant vaccine based on the hybrid recombinant protein

Медицинская иммунология, 2020
A hybrid recombinant protein containing the amino  acid sequences of the three  most significant Pseudomonas aeruginosa antigens  (membrane proteins OprF, OprI  and toxoid  aTox)  was incorporated into a vaccine against Pseudomonas infection.
A. V. Soldatenkova, A. M. Kudryashova, N. F. Gavrilova, I. V. Yakovleva, O. V. Borisova, V. V. Sviridov, N. A. Mikhailova   +6 more
doaj   +1 more source

Monoclonal antibodies against peptidorhamnomannans of Scedosporium apiospermum enhance the pathogenicity of the fungus. [PDF]

PLoS Neglected Tropical Diseases, 2010
Scedosporium apiospermum is part of the Pseudallescheria-Scedosporium complex. Peptidorhamnomannans (PRMs) are cell wall glycopeptides present in some fungi, and their structures have been characterized in S. apiospermum, S.
Livia C L Lopes, Rodrigo Rollin-Pinheiro, Allan J Guimarães, Vera C B Bittencourt, Luis R Martinez, Wade Koba, Sandra E Farias, Joshua D Nosanchuk, Eliana Barreto-Bergter   +8 more
doaj   +1 more source

Proinflammatory Action of a New Electronegative Low-Density Lipoprotein Epitope

Biomolecules, 2019
The electronegative low-density lipoprotein, LDL (−), is an endogenously modified LDL subfraction with cytotoxic and proinflammatory actions on endothelial cells, monocytes, and macrophages contributing to the progression of atherosclerosis.
Tanize do Espirito Santo Faulin, Soraya Megumi Kazuma, Gustavo Luis Tripodi, Marcela Frota Cavalcante, Felipe Wakasuqui, Cristiano Luis Pinto Oliveira, Maximilia Frazão de Souza Degenhardt, Jussara Michaloski, Ricardo José Giordano, Daniel Francisco Jacon Ketelhuth, Dulcineia Saes Parra Abdalla   +10 more
doaj   +1 more source

Production and characterisation of monoclonal antibodies for the detection of AOZ, a tissue bound metabolite of furazolidone

Veterinární Medicína, 2005
3-amino-2-oxazolidinone (AOZ) is a tissue bound toxic metabolite derived from the nitrofuran antibiotic, furazolidone. AOZ is detected in the derivatised form of 3-{[(2-nitrophenyl) methylene] amino}-2-oxa-zolidinone (NP AOZ).
M. Vass, L. Kotkova, I. Diblikova, Z. Nevorankova, K.M. Cooper, D.G. Kennedy, M. Franek   +6 more
doaj   +1 more source

Comparison of Bacterial Expression Systems Based on Potato Virus Y-like Particles for Vaccine Generation

Vaccines, 2022
Plant-based virus-like particle (VLP) vaccines have been studied for years, demonstrating their potential as antigen-presenting platforms. In this paper, we describe the development of, and compare between, simple Escherichia coli-based antigen display ...
Anete Ogrina, Dace Skrastina, Ina Balke, Ieva Kalnciema, Juris Jansons, Martin F. Bachmann, Andris Zeltins   +6 more
doaj   +1 more source

A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.

PLoS Pathogens, 2022
Potent and durable vaccine responses will be required for control of malaria caused by Plasmodium falciparum (Pf). RTS,S/AS01 is the first, and to date, the only vaccine that has demonstrated significant reduction of clinical and severe malaria in ...
Nathan Beutler, Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Randall S MacGill, Elijah Garcia, Jaeson Calla, Mara Parren, Linlin Yang, Wayne Volkmuth, Emily Locke, Jason A Regules, Sheetij Dutta, Daniel Emerling, Angela M Early, Daniel E Neafsey, Elizabeth A Winzeler, C Richter King, Fidel Zavala, Dennis R Burton, Ian A Wilson, Thomas F Rogers   +21 more
doaj   +1 more source

Antibodies to antigenic site A of influenza H7 hemagglutinin provide protection against H7N9 challenge.

PLoS ONE, 2015
Identifying major antigenic and protective epitopes of the H7 hemagglutinin (HA) will be important for understanding the antibody response to vaccines developed against the novel influenza H7N9 viruses that emerged in China in 2013.
Falko Schmeisser, Anupama Vasudevan, Swati Verma, Wei Wang, Esmeralda Alvarado, Carol Weiss, Vajini Atukorale, Clement Meseda, Jerry P Weir   +8 more
doaj   +1 more source