Results 11 to 20 of about 236,432 (265)

Establishment and Functional Characterization of Murine Monoclonal Antibodies Recognizing Neuritin

open access: yesAntibodies, 2023
Neuritin represents a neurotrophic factor that is not only important in neuronal development and plasticity but also impacts endothelial angiogenesis, cell migration, tumor growth and the production of antibodies by B cells.
Georgia Papadogianni   +6 more
doaj   +1 more source

The mosaic puzzle of the therapeutic monoclonal antibodies and antibody fragments - A modular transition from full-length immunoglobulins to antibody mimetics

open access: yesLeukemia Research Reports, 2022
The use of monoclonal antibodies represents an important and efficient diagnostic and therapeutic tool in disease management and modern science but remains limited by several factors including the uneven distribution in diseased tissues as well as ...
Sami El Khatib, Mohamed Salla
doaj   +1 more source

Development of canine parvovirus-neutralizing monoclonal antibodies from natural host and their germline gene usage. [PDF]

open access: yesAppl Microbiol Biotechnol
Canine parvovirus 2 (CPV-2) remains a leading cause of acute infectious gastroenteritis with high global morbidity in dogs. While murine neutralizing monoclonal antibodies (mAbs) are widely used for antiviral therapy, their efficacy is limited by immune ...
Liu G   +8 more
europepmc   +2 more sources

Inducible immortalized Dendritic Cells enable antigen-specific antibody production in a murine in vitro Immunization model. [PDF]

open access: yesPLoS One
Transferring the complexity of the in vivo immune response into a controlled in vitro system represents a promising strategy for the rapid generation of antigen-specific antibodies while significantly reducing the reliance on animal experimentation, thus
Egert J, Maier N, Micheel B, Hanack K.
europepmc   +2 more sources

Radioimmunotherapy of lymphoma [PDF]

open access: yesArchive of Oncology, 2012
Radiolabeled monoclonal antibodies for the treatment of follicular low-grade non-Hodgkin’s lymphoma have been available for several years in the United States and more recently throughout Europe.
Goldsmith Stanley J.
doaj   +1 more source

Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections

open access: yesNature Communications, 2021
Although enterovirus D68 poses a major global threat to children, neither vaccines nor therapeutics are currently available. Using Cryo-EM, Zhang et al.
Chao Zhang   +10 more
doaj   +1 more source

Progress on Phage Display Technology: Tailoring Antibodies for Cancer Immunotherapy

open access: yesViruses, 2023
The search for innovative anti-cancer drugs remains a challenge. Over the past three decades, antibodies have emerged as an essential asset in successful cancer therapy.
Renato Kaylan Alves França   +7 more
doaj   +1 more source

Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies

open access: yesCell Reports, 2021
Summary: An effective HIV-1 vaccine will likely need to elicit broadly neutralizing antibodies (bNAbs). Broad and potent VRC01-class bNAbs have been isolated from multiple infected individuals, suggesting that they could be reproducibly elicited by ...
Emilie Seydoux   +13 more
doaj   +1 more source

Investigation of a monoclonal antibody against enterotoxigenic Escherichia coli, expressed as secretory IgA1 and IgA2 in plants

open access: yesGut Microbes, 2021
Passive immunization with antibodies is a promising approach against enterotoxigenic Escherichia coli diarrhea, a prevalent disease in LMICs. The objective of this study was to investigate expression of a monoclonal anti-ETEC CfaE secretory IgA antibody ...
Audrey Y-H Teh   +13 more
doaj   +1 more source

Applications of Antibody-Based Antigen Delivery Targeted to Dendritic Cells In Vivo

open access: yesAntibodies, 2022
Recombinant immunoglobulins, derived from monoclonal antibodies recognizing the defined surface epitopes expressed on dendritic cells, have been employed for the past two decades to deliver antigens to dendritic cells in vivo, serving as critical tools ...
Jessica Bourque, Daniel Hawiger
doaj   +1 more source

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