Results 11 to 20 of about 3,631,784 (211)
Establishment and Functional Characterization of Murine Monoclonal Antibodies Recognizing Neuritin
Antibodies, 2023 Neuritin represents a neurotrophic factor that is not only important in neuronal development and plasticity but also impacts endothelial angiogenesis, cell migration, tumor growth and the production of antibodies by B cells.
Georgia Papadogianni +6 more
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Radioimmunotherapy of lymphoma [PDF]
Archive of Oncology, 2012 Radiolabeled monoclonal antibodies for the treatment of follicular low-grade non-Hodgkin’s lymphoma have been available for several years in the United States and more recently throughout Europe.
Goldsmith Stanley J.
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Leukemia Research Reports, 2022 The use of monoclonal antibodies represents an important and efficient diagnostic and therapeutic tool in disease management and modern science but remains limited by several factors including the uneven distribution in diseased tissues as well as ...
Sami El Khatib, Mohamed Salla
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Nature Communications, 2021 Although enterovirus D68 poses a major global threat to children, neither vaccines nor therapeutics are currently available. Using Cryo-EM, Zhang et al.
Chao Zhang +10 more
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Progress on Phage Display Technology: Tailoring Antibodies for Cancer Immunotherapy
Viruses, 2023 The search for innovative anti-cancer drugs remains a challenge. Over the past three decades, antibodies have emerged as an essential asset in successful cancer therapy.
Renato Kaylan Alves França +7 more
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Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies
Cell Reports, 2021 Summary: An effective HIV-1 vaccine will likely need to elicit broadly neutralizing antibodies (bNAbs). Broad and potent VRC01-class bNAbs have been isolated from multiple infected individuals, suggesting that they could be reproducibly elicited by ...
Emilie Seydoux +13 more
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Gut Microbes, 2021 Passive immunization with antibodies is a promising approach against enterotoxigenic Escherichia coli diarrhea, a prevalent disease in LMICs. The objective of this study was to investigate expression of a monoclonal anti-ETEC CfaE secretory IgA antibody ...
Audrey Y-H Teh +13 more
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Applications of Antibody-Based Antigen Delivery Targeted to Dendritic Cells In Vivo
Antibodies, 2022 Recombinant immunoglobulins, derived from monoclonal antibodies recognizing the defined surface epitopes expressed on dendritic cells, have been employed for the past two decades to deliver antigens to dendritic cells in vivo, serving as critical tools ...
Jessica Bourque, Daniel Hawiger
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Production and N-glycan engineering of Varlilumab in Nicotiana benthamiana
Frontiers in Plant Science, 2023 N-glycan engineering has dramatically evolved for the development and quality control of recombinant antibodies. Fc region of IgG contains two N-glycans whose galactose terminals on Fc-glycan have been shown to increase the stability of CH2 domain and ...
Kim Dua Nguyen +9 more
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Arginine mutation alters binding of a human monoclonal antibody to antigens linked to systemic lupus erythematosus and the antiphospholipid syndrome [PDF]
, 2007 Objective: Previous studies have shown the importance of somatic mutations and arginine residues in the complementarity-determining regions (CDRs) of pathogenic anti-double-stranded DNA (anti-dsDNA) antibodies in human and murine lupus, and in studies of
Yiannis Ioannou +15 more
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