Results 31 to 40 of about 2,524,488 (277)

Kaplan-Meier curve for overall survival with respect to the proportion of D2-40-positive stained sinus in SLN.

, 2023
According to the optimal cutoff point determined by the Cutoff Finder algorithm, overall survival was plotted for the proportion of D2-40 positive stained subcapsular sinus in sentinel lymph nodes.
Sabrina K. Müller (14498354), Roland Moll (567031), Paul Jank (9300030), Matthias Kalder (3533060), Christina C. Westhoff (14498351)   +4 more
core   +1 more source

The utility of CD44 and D2-40 as a prognostic predictor in invasive carcinomas of the breast [PDF]

Korean Journal of Clinical Oncology, 2013
Purpose:Local recurrence and distant metastasis are major prognostic factors associated with breast cancer. Lymphovascular invasion is an important pathway of metastatic spread. CD44 and D2-40 are assumed to be related with invasion of malignant cells to
Jung Whan Chun, Yeo Goo Chang, Seong Woo Hong, Woo Yong Lee, Byungmo Lee, Hye Kyung Lee   +5 more
doaj   +1 more source

Comparison of lymphangiogenesis, lymphatic invasion, and axillary lymph node metastasis in breast carcinoma

Indian Journal of Pathology and Microbiology, 2018
Context: Lymphangiogenesis correlates with poor prognosis in Invasive Ductal Carcinoma (IDC) breast. D2-40 antibody, a specific marker for lymphatic endothelium, differentiates lymphatic from vascular endothelium.
Prerna Guleria, V Srinivas, D Basannar, Vibha Dutta   +3 more
doaj   +1 more source

Lymphangiogenesis in breast carcinoma is present but insufficient for metastatic spread

Journal of Health Sciences, 2014
Introduction: The lymphatic vasculature is an important route for the metastatic spread of human cancer. However, the extent to which this depends on lymphangiogenesis or on invasion of existing lymph vessels remains controversial. The goal of this study
Mirsad Dorić, Suada Kuskunović-Vlahovljak, Svjetlana Radović, Ajna Hukić, Mirsad Babić, Edina Lazović-Salčin   +5 more
doaj   +1 more source

Peritoneal Elastic Lamina Changes and D2-40 Expression in Colorectal Carcinoma: A Histopathological and Immunohistochemical Study [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Peritoneal Elastic Lamina Invasion (PELI) has been reported as an important negative prognostic factor in pT3 Colorectal Cancer (CRC). Lymphovascular Invasion (LVI) is a crucial step in the dissemination of tumour cells and is correlated ...
Ahmed Mahmoud Abd El-Aziz, Hanan Hassan Mohammad Ali, Sahar Abd El-Hamid Tabak, Yasmine Fathi Ghazi El-Esawy, Abeer Mohammad Amal   +4 more
doaj   +1 more source

Evaluation of lymphatic regeneration in rat incisional wound healing and its use in wound age estimation

Alexandria Journal of Medicine, 2015
Objective: During the wound healing process, lymphatic regeneration in the injured skin has not been fully investigated. This work was designed to study the regeneration of lymphatic vessels in rat incisional wounds in relation to the duration after the ...
Nevine M.F. El Deeb, Fatma M. Badr El Dine   +1 more
doaj   +1 more source

Utility of D2-40, a novel mesothelial marker, in the diagnosis of malignant mesothelioma [PDF]

Modern Pathology, 2005
Although immunohistochemistry has proven to be valuable in the differentiation of epithelioid mesothelioma from pulmonary or metastatic adenocarcinoma, no single antibody has demonstrated absolute sensitivity or specificity in making this distinction. Using immunohistochemical analysis with D2-40, a recently available monoclonal antibody that has been ...
Albert Y, Chu, Leslie A, Litzky, Theresa L, Pasha, Geza, Acs, Paul J, Zhang   +4 more
openaire   +2 more sources

Nodal lymphangiogenesis and immunophenotypic variations of sinus endothelium in sentinel and non-sentinel lymph nodes of invasive breast carcinoma

PLoS ONE, 2023
Several studies have demonstrated the de novo formation of lymphatic vessels or the reorganization of lymphatic sinus in tumor-draining lymph nodes, partly preceding the detection of lymphatic metastases.
Christina C. Westhoff, Sabrina K. Müller, Paul Jank, Matthias Kalder, Roland Moll   +4 more
doaj   +2 more sources

Hypomorphic Mutations in the Central Fanconi Anemia Gene FANCD2 Sustain a Significant Group of FA-D2 Patients with Severe Phenotype. Running title : FA-D2 phenotype and FANCD2 mutations

, 2007
Premi a l'excel·lència investigadora. Àmbit de les Ciències de la Salut. 2008FANCD2 is an evolutionarily conserved Fanconi anemia (FA) gene that plays a central role in DNA double-strand type damage responses.
Detlev Schindler, Casado, José A., Surrallés, Jordi, Bueren, Juan, Schindler, Detlev, Arleen D. Auerbach, Holger Hoehn, Schneider, Hildegard, Kornelia Neveling, Elsa Callén, Kalba, Reinhard, Berwick, Marianne, Jean Soulier, Hunt, Curtis, Pals, Gerard, Rosalina van Spaendonk, Gluckman, Eliane, Callén Moréu, Elsa, Joenje, Hans, Kalb, Reinhard, Batish, Sat Dev, Soulier, Jean, Juan Bueren, Hanenberg, Helmut, Helmut Hanenberg, C. Michel Zwaan, Linka, Yvonne, Winter, Johan P. de, Eliane Gluckman, Neveling, Kornelia, Yvonne Linka, Hans Joenje, Markus Grompe, Johan P. de Winter, Grompe, Markus, Zwaan, C. Michel, Surrallés i Calonge, Jordi, Reinhard Kalb, Hoehn, Holger, Auerbach, Arleen D., Jordi Surrallés, Ángeles Dasí, de Winter, Johan P., Dasí, Ángeles, Marianne Berwick, José A. Casado, Sat Dev Batish, Curtis Hunt, Van Spaendonk, Rosalina, Callén, Elsa, Hildegard Schneider, Batishb, Sat Dev, Gerard Pals   +52 more
core   +1 more source

Tumor cell invasion in blood vessels assessed by immunohistochemistry is related to decreased survival in patients with bladder cancer treated with radical cystectomy

Diagnostic Pathology, 2021
Background Lymphovascular invasion (VI) is an established prognostic marker for many cancers including bladder cancer. There is a paucity of data regarding whether the prognostic significance of lymphatic invasion (LVI) differs from blood vessel invasion
Birgitte Carlsen, Tor Audun Klingen, Bettina Kulle Andreassen, Erik Skaaheim Haug   +3 more
doaj   +1 more source