Results 1 to 10 of about 9,519 (118)

The Role of Podoplanin in the Immune System and Inflammation

open access: yesJournal of Inflammation Research, 2022
Zhiyuan Zhang,* Nan Zhang,* Jing Yu,* Wenting Xu, Jiameng Gao, Xin Lv, Zongmei Wen Department of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200433, People’s Republic of China*These ...
Zongmei Wen, Xin Lv, Zhiyuan Zhang
exaly   +2 more sources

Elevated Serum Podoplanin Levels Correlate with Disease Severity and Inflammation in Ulcerative Colitis: A Cross-Sectional Study [PDF]

open access: yesJournal of Inflammation Research
Xiaogang Huang,1 Caifang Tang2 1Department of Gastroenterology, Sijing Hospital, Shanghai, 201601, People’s Republic of China; 2Department of Nursing, Sijing Hospital, Shanghai, 201601, People’s Republic of ChinaCorrespondence: Caifang Tang, Department ...
Huang X, Tang C
doaj   +2 more sources

Role of Podoplanin-Positive Cells in Cardiac Fibrosis and Angiogenesis After Ischemia

open access: yesFrontiers in Physiology, 2021
New insights into the cellular and extra-cellular composition of scar tissue after myocardial infarction (MI) have been identified. Recently, a heterogeneous podoplanin-expressing cell population has been associated with fibrogenic and inflammatory ...
Maria Cimini, Raj Kishore
doaj   +1 more source

Differential expression of podoplanin in metastatic lymph node is associated with extranodal extension in oropharyngeal cancer

open access: yesScientific Reports, 2022
This study aimed to investigate the spatial distribution and clinical significance of podoplanin expression in the metastatic lymph nodes of oropharyngeal squamous cell carcinomas (OPSCCs).
Hye Ran Lee   +6 more
doaj   +1 more source

Podoplanin expression in lymph node metastases of head and neck cancer and cancer of unknown primary patients

open access: yesThe International Journal of Biological Markers, 2022
Introduction Head and neck squamous cell carcinomas (HNSCCs) are cancers with generally poor prognosis. Outcomes have not improved in decades, with more than half of the patients presenting with lymph node metastases at the time of diagnosis.
Jan Philipp Kühn   +10 more
doaj   +1 more source

Expression of Podoplanin in Laryngeal Squamous Cell Carcinoma and Dysplasia [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Introduction: In human cancers, podoplanin expression and its correlation with tumour invasive potential raise its possible role as a diagnostic and prognostic marker for cancer. Aim: To investigate the immunohistochemical expression of podoplanin in
Badawia Bayoumy Ibrahim   +3 more
doaj   +1 more source

Podoplanin Expression Independently and Jointly with Oral Epithelial Dysplasia Grade Acts as a Potential Biomarker of Malignant Transformation in Oral Leukoplakia

open access: yesBiomolecules, 2022
Our aim was to evaluate the expression of biomarkers, CD44v6, CD147, EGFR, p53, p63, p73, p16, and podoplanin in oral leukoplakias (OL) and to assess their potential for prediction of malignant transformation (MT).
Luís Monteiro   +7 more
doaj   +1 more source

Podoplanin drives dedifferentiation and amoeboid invasion of melanoma

open access: yesiScience, 2021
Summary: Melanoma is an aggressive skin cancer developing from melanocytes, frequently resulting in metastatic disease. Melanoma cells utilize amoeboid migration as mode of local invasion. Amoeboid invasion is characterized by rounded cell morphology and
Charlotte M. de Winde   +12 more
doaj   +1 more source

Interplay between Podoplanin, CD44s and CD44v in Squamous Carcinoma Cells

open access: yesCells, 2020
Podoplanin and CD44 are transmembrane glycoproteins involved in inflammation and cancer. In this paper, we report that podoplanin is coordinately expressed with the CD44 standard (CD44s) and variant (CD44v) isoforms in vivo—in hyperplastic skin after a ...
Lucía Montero-Montero   +7 more
doaj   +1 more source

Roles of the CLEC-2–podoplanin interaction in tumor progression

open access: yesPlatelets, 2018
Podoplanin is a type-I transmembrane sialomucin-like glycoprotein expressed on the surface of several kinds of tumor cells. The podoplanin receptor is a platelet activation receptor known as C-type lectin-like receptor 2 (CLEC-2), which has been ...
Katsue Suzuki-Inoue
doaj   +1 more source

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