Results 1 to 10 of about 9,206 (117)

The Role of Podoplanin in the Immune System and Inflammation

Journal of Inflammation Research, 2022
Zhiyuan Zhang,* Nan Zhang,* Jing Yu,* Wenting Xu, Jiameng Gao, Xin Lv, Zongmei Wen Department of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200433, People’s Republic of China*These ...
Zhiyuan Zhang, Jiameng Gao, Xin Lv
exaly   +2 more sources

Elevated Serum Podoplanin Levels Correlate with Disease Severity and Inflammation in Ulcerative Colitis: A Cross-Sectional Study [PDF]

Journal of Inflammation Research
Xiaogang Huang,1 Caifang Tang2 1Department of Gastroenterology, Sijing Hospital, Shanghai, 201601, People’s Republic of China; 2Department of Nursing, Sijing Hospital, Shanghai, 201601, People’s Republic of ChinaCorrespondence: Caifang Tang, Department ...
Huang X, Tang C
doaj   +2 more sources

Evaluation of podoplanin expression in vulvar squamous cell carcinoma and stromal fibroblasts and its prognostic implications [PDF]

Scientific Reports
Although the immunohistochemical expression of the transmembrane sialoglycoprotein podoplanin (D2-40) has been repeatedly reported as a factor of prognosis in various tumor entities—its potential prognostic relevance in squamous cell carcinomas of the ...
Gilbert Georg Klamminger, Meletios P. Nigdelis, Annick Bitterlich, Mariam Parvanta, Martin Ertz, Laura Schnöder, Bernd Holleczek, Roxana Schwab, Annette Hasenburg, Bashar Haj Hamoud, Erich Franz Solomayer, Mathias Wagner   +11 more
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Role of Podoplanin-Positive Cells in Cardiac Fibrosis and Angiogenesis After Ischemia

Frontiers in Physiology, 2021
New insights into the cellular and extra-cellular composition of scar tissue after myocardial infarction (MI) have been identified. Recently, a heterogeneous podoplanin-expressing cell population has been associated with fibrogenic and inflammatory ...
Maria Cimini, Raj Kishore
doaj   +1 more source

Differential expression of podoplanin in metastatic lymph node is associated with extranodal extension in oropharyngeal cancer

Scientific Reports, 2022
This study aimed to investigate the spatial distribution and clinical significance of podoplanin expression in the metastatic lymph nodes of oropharyngeal squamous cell carcinomas (OPSCCs).
Hye Ran Lee, Jin Roh, Ga Young Gu, Ju Ho Lee, Yoo Seob Shin, Jeon Yeob Jang, Chul-Ho Kim   +6 more
doaj   +1 more source

Expression of Podoplanin in Laryngeal Squamous Cell Carcinoma and Dysplasia [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: In human cancers, podoplanin expression and its correlation with tumour invasive potential raise its possible role as a diagnostic and prognostic marker for cancer. Aim: To investigate the immunohistochemical expression of podoplanin in
Badawia Bayoumy Ibrahim, Mostafa Mohamed Salem, Rasha Ahmed Khairy, Reema Abdul Rahman AL Gunaid   +3 more
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Podoplanin expression in lymph node metastases of head and neck cancer and cancer of unknown primary patients

The International Journal of Biological Markers, 2022
Introduction Head and neck squamous cell carcinomas (HNSCCs) are cancers with generally poor prognosis. Outcomes have not improved in decades, with more than half of the patients presenting with lymph node metastases at the time of diagnosis.
Jan Philipp Kühn, Florian Bochen, Sandrina Körner, Bernhard Schick, Mathias Wagner, Sigrun Smola, Barbara Berkó-Göttel, Luc G.T. Morris, Jingming Wang, Alessandro Bozzato, Maximilian Linxweiler   +10 more
doaj   +1 more source

Podoplanin Expression Independently and Jointly with Oral Epithelial Dysplasia Grade Acts as a Potential Biomarker of Malignant Transformation in Oral Leukoplakia

Biomolecules, 2022
Our aim was to evaluate the expression of biomarkers, CD44v6, CD147, EGFR, p53, p63, p73, p16, and podoplanin in oral leukoplakias (OL) and to assess their potential for prediction of malignant transformation (MT).
Luís Monteiro, Barbas do Amaral, Leonor Delgado, Fernanda Garcês, Filomena Salazar, José Júlio Pacheco, Carlos Lopes, Saman Warnakulasuriya   +7 more
doaj   +1 more source

Podoplanin in cancer cells is experimentally able to attenuate prolymphangiogenic and lymphogenous metastatic potentials of lung squamoid cancer cells

Molecular Cancer, 2010
Background Podoplanin, a mucin-like transmembrane glycoprotein, is reportedly expressed in a variety of malignant cells and is generally regarded as a factor for promoting tumor progression in conventional studies.
Suzuki Hanako, Onimaru Mitsuho, Yonemitsu Yoshikazu, Maehara Yoshihiko, Nakamura Seiji, Sueishi Katsuo   +5 more
doaj   +1 more source

Interplay between Podoplanin, CD44s and CD44v in Squamous Carcinoma Cells

Cells, 2020
Podoplanin and CD44 are transmembrane glycoproteins involved in inflammation and cancer. In this paper, we report that podoplanin is coordinately expressed with the CD44 standard (CD44s) and variant (CD44v) isoforms in vivo—in hyperplastic skin after a ...
Lucía Montero-Montero, Jaime Renart, Andrés Ramírez, Carmen Ramos, Mariam Shamhood, Rocío Jarcovsky, Miguel Quintanilla, Ester Martín-Villar   +7 more
doaj   +1 more source