Results 1 to 10 of about 9,519 (118)
The Role of Podoplanin in the Immune System and Inflammation
Zhiyuan Zhang,* Nan Zhang,* Jing Yu,* Wenting Xu, Jiameng Gao, Xin Lv, Zongmei Wen Department of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200433, People’s Republic of China*These ...
Zongmei Wen, Xin Lv, Zhiyuan Zhang
exaly +2 more sources
Elevated Serum Podoplanin Levels Correlate with Disease Severity and Inflammation in Ulcerative Colitis: A Cross-Sectional Study [PDF]
Xiaogang Huang,1 Caifang Tang2 1Department of Gastroenterology, Sijing Hospital, Shanghai, 201601, People’s Republic of China; 2Department of Nursing, Sijing Hospital, Shanghai, 201601, People’s Republic of ChinaCorrespondence: Caifang Tang, Department ...
Huang X, Tang C
doaj +2 more sources
Role of Podoplanin-Positive Cells in Cardiac Fibrosis and Angiogenesis After Ischemia
New insights into the cellular and extra-cellular composition of scar tissue after myocardial infarction (MI) have been identified. Recently, a heterogeneous podoplanin-expressing cell population has been associated with fibrogenic and inflammatory ...
Maria Cimini, Raj Kishore
doaj +1 more source
This study aimed to investigate the spatial distribution and clinical significance of podoplanin expression in the metastatic lymph nodes of oropharyngeal squamous cell carcinomas (OPSCCs).
Hye Ran Lee +6 more
doaj +1 more source
Introduction Head and neck squamous cell carcinomas (HNSCCs) are cancers with generally poor prognosis. Outcomes have not improved in decades, with more than half of the patients presenting with lymph node metastases at the time of diagnosis.
Jan Philipp Kühn +10 more
doaj +1 more source
Expression of Podoplanin in Laryngeal Squamous Cell Carcinoma and Dysplasia [PDF]
Introduction: In human cancers, podoplanin expression and its correlation with tumour invasive potential raise its possible role as a diagnostic and prognostic marker for cancer. Aim: To investigate the immunohistochemical expression of podoplanin in
Badawia Bayoumy Ibrahim +3 more
doaj +1 more source
Our aim was to evaluate the expression of biomarkers, CD44v6, CD147, EGFR, p53, p63, p73, p16, and podoplanin in oral leukoplakias (OL) and to assess their potential for prediction of malignant transformation (MT).
Luís Monteiro +7 more
doaj +1 more source
Podoplanin drives dedifferentiation and amoeboid invasion of melanoma
Summary: Melanoma is an aggressive skin cancer developing from melanocytes, frequently resulting in metastatic disease. Melanoma cells utilize amoeboid migration as mode of local invasion. Amoeboid invasion is characterized by rounded cell morphology and
Charlotte M. de Winde +12 more
doaj +1 more source
Interplay between Podoplanin, CD44s and CD44v in Squamous Carcinoma Cells
Podoplanin and CD44 are transmembrane glycoproteins involved in inflammation and cancer. In this paper, we report that podoplanin is coordinately expressed with the CD44 standard (CD44s) and variant (CD44v) isoforms in vivo—in hyperplastic skin after a ...
Lucía Montero-Montero +7 more
doaj +1 more source
Roles of the CLEC-2–podoplanin interaction in tumor progression
Podoplanin is a type-I transmembrane sialomucin-like glycoprotein expressed on the surface of several kinds of tumor cells. The podoplanin receptor is a platelet activation receptor known as C-type lectin-like receptor 2 (CLEC-2), which has been ...
Katsue Suzuki-Inoue
doaj +1 more source

