Results 21 to 30 of about 11,070 (170)
The role of podoplanin inhibitors in controlling oral cancer progression [PDF]
, 2023 Objective: In this article, we review the current studies on the role of podoplanin in oral cancer and the potential application of podoplanin inhibitors as a therapeutic agent for oral cancer.
Engku Ngah Sayuddin, Engku Nasiha +4 more
core +1 more source
Evaluation of podoplanin levels in odontogenic cysts
, 2021 This study evaluated role of podoplanin levels in odontogenic cysts. We concluded that expression of podoplanin was significantly higher in KCOTs than in dentigerous cysts & dental ...
Nayar, Amit K +3 more
core +1 more source
Assessment of expression of podoplanin in odontogenic tumors and cysts—An immunohistochemical study
Journal of Family Medicine and Primary Care, 2020 Aim: The present study was conducted to determine the podoplanin expression in odontogenic tumors and cysts. Materials and Methods: It consisted of 12 cases of the keratocystic odontogenic tumor (KCOT), 10 cases of ameloblastoma, 8 cases of dentigerous ...
Rohit Singh +5 more
doaj +1 more source
Podoplanin: Its roles and functions in neurological diseases and brain cancers
Frontiers in Pharmacology, 2022 Podoplanin is a small mucin-like glycoprotein involved in several physiological and pathological processes in the brain including development, angiogenesis, tumors, ischemic stroke and other neurological disorders. Podoplanin expression is upregulated in
Yi Wang +5 more
doaj +1 more source
Are podoplanin and ezrin involved in the invasion process of the ameloblastomas?
European Journal of Histochemistry, 2015 The association between podoplanin and ezrin in the process of odontogenic tumors invasion has been suggested, but was not studied yet. Our purpose was to investigate the relationship between podoplanin and ezrin expressions in the odontogenic epithelium
Y.F. Costa +5 more
doaj +1 more source
Indian Journal of Dental Sciences, 2021 Background: Odontogenic lesions can bring about diagnostic challenges due to overlapping histology among pathologists. Thus, there are few tumor markers that provide accurate diagnosis.
Alka Chahar +4 more
doaj +1 more source
New trends in the study of podoplanin as a cell morphological regulator
Japanese Dental Science Review, 2010 Podoplanin is a mucin-type glycoprotein firstly identified in podocytes, which is homologous to the type I alveolar cell specific T1α-2 antigen and to the oncofetal antigen M2A recognized by the D2-40 antibody. Podoplanin possesses a platelet aggregation-
Yoshihiko Sawa
doaj +1 more source
Podoplanin enhances lung cancer cell growth in vivo by inducing platelet aggregation
Scientific Reports, 2017 Podoplanin/Aggrus, known as a platelet aggregation-inducing factor, is frequently overexpressed in lung squamous cell carcinomas (LSCC) and glioblastomas among other tumours, and its expression has been reported to be correlated with poor prognosis ...
Kenichi Miyata +4 more
doaj +1 more source
PLoS ONE, 2017 In our previous studies we showed that in breast cancer podoplanin-positive cancer-associated fibroblasts correlated positively with tumor size, grade of malignancy, lymph node metastasis, lymphovascular invasion and poor patients' outcome.
Jaroslaw Suchanski +10 more
doaj +1 more source
Indian Journal of Dermatology, 2020 Background: Podoplanin, an important protein, has been implicated in various cellular processes, including lymphangiogenesis. Podoplanin is a mucin-type transmembrane glycoprotein that is accepted as a novel marker of lymphatic endothelial cells ...
Amal A El-Ashmawy +2 more
doaj +1 more source