Results 11 to 20 of about 11,879 (214)
The Role of Podoplanin in Skin Diseases [PDF]
The Nishinihon Journal of Dermatology, 2022 Podoplanin is a sialomucin-like type I transmembrane receptor glycoprotein that is expressed specifically in lymphatic vessels, sebaceous glands, and hair follicles in normal skin.
Jun Asai
core +3 more sources
The spectrum of podoplanin expression in encapsulating peritoneal sclerosis. [PDF]
PLoS ONE, 2012 Encapsulating peritoneal sclerosis (EPS) is a life threatening complication of peritoneal dialysis (PD). Podoplanin is a glycoprotein expressed by mesothelial cells, lymphatic endothelial cells, and myofibroblasts in peritoneal biopsies from patients ...
Niko Braun +12 more
doaj +2 more sources
Morphological study of tooth development in podoplanin-deficient mice. [PDF]
PLoS ONE, 2017 Podoplanin is a mucin-type highly O-glycosylated glycoprotein identified in several somatyic cells: podocytes, alveolar epithelial cells, lymphatic endothelial cells, lymph node stromal fibroblastic reticular cells, osteocytes, odontoblasts, mesothelial ...
Kenyo Takara +9 more
doaj +2 more sources
The multifaceted role of podoplanin expression in hepatocellular carcinoma
European Journal of Histochemistry, 2017 The role of podoplanin in hepatocellular carcinoma (HCC) is not clear yet. The aim of our study was to evaluate the expression of podoplanin in HCC and to determine its role in hepatocarcinogenesis. We performed immunohistochemistry with monoclonal D2-40
Andreea Cioca +4 more
doaj +3 more sources
Podoplanin expression in the development and progression of laryngeal squamous cell carcinomas [PDF]
Molecular Cancer, 2010 Background Podoplanin expression is attracting interest as a marker for cancer diagnosis and prognosis. We therefore investigated the expression pattern and clinical significance of podoplanin during the development and progression of laryngeal ...
Fresno Manuel F +5 more
doaj +4 more sources
Prognostic Value of Podoplanin in Various Tumors [PDF]
Technology in Cancer Research & Treatment, 2021 Background: The prognostic significance of podoplanin (PDPN) in tumor cells for cancer patients’ survival remains controversial. Therefore, we performed this meta-analysis to clarify the relationship between the podoplanin-positive tumor cells and cancer
Xiaohang Wang PhD +9 more
doaj +3 more sources
Protein O-Glycosylation Shapes Lymphatic Endothelia and Lymph Node Macrophage Populations. [PDF]
FASEB JTo study the functional roles of O‐glycans on lymphatic endothelia, we deleted Cosmc, the chaperone required for core‐1 O‐glycan synthesis. Loss of core‐1 O‐glycans entailed major changes in glycoprotein composition of lymphatic endothelial cells (LEC), including reduced podoplanin (Pdpn), CD44, and Lyve‐1, and increased ICAM‐1; reduced CD44 was caused
Frey J +11 more
europepmc +2 more sources
Hepatology, EarlyView., 2022 Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog +12 more
wiley +1 more source
Evaluation of podoplanin levels in odontogenic cysts [PDF]
, 2021 This study evaluated role of podoplanin levels in odontogenic cysts. We concluded that expression of podoplanin was significantly higher in KCOTs than in dentigerous cysts & dental ...
Nayar, Amit K +3 more
core +1 more source
The landscape of ‘podoplanin’ in dermatology
Journal of the Egyptian Women's Dermatologic Society, 2021 Podoplanin (PDPN) is a specific marker for lymphatic endothelial cells; however, it can be expressed by many other cells including renal podocytes. In dermatology, PDPN has been involved in diverse disorders, such as tumor lymphangiogenesis, as well as in immune-mediated disorders.
Nagwa Diab +3 more
openaire +2 more sources