Results 31 to 40 of about 11,070 (170)

Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures

, 2013
Insertion of bone substitution materials accelerates healing of osteoporotic fractures. Biodegradable materials are preferred for application in osteoporotic patients to avoid a second surgery for implant replacement. Degraded implant fragments are often
Vivien Kauschke, Hartmann, Sonja, Alexander Langheinrich, Matthias Schumacher, Matthias Schnabelrauch, Hanke, Thomas, Heiss, Christian, Olaf Kilian, Kauschke, Vivien, Sonja Hartmann, Christian Heiss, Alt, Volker, Heinemann, Sascha, Marian Kampschulte, Kilian, Olaf, Thormann, Ulrich, Lips, Katrin Susanne, Langheinrich, Alexander, Schumacher, Matthias, Michael Gelinsky, Armin R Kautz, Seemun Ray, Volker Alt, Kautz, Armin R, Kampschulte, Marian, Katrin Susanne Lips, Gelinsky, Michael, Ray, Seemun, Schnettler, Reinhard, Sascha Heinemann, Reinhard Schnettler, Ulrich Thormann, Schnabelrauch, Matthias, Kautz, Armin R., Thomas Hanke   +34 more
core   +1 more source

Immunohistochemical study of vascular endothelial growth factor‑C/vascular endothelial growth factor receptor‑3 expression in oral tongue squamous cell carcinoma: Correlation with the induction of lymphangiogenesis

, 2015
The aim of the present study was to elucidate the associations between the expression of the vascular endothelial growth factor-C (VEGF-C)/VEGF receptor-3 (VEGFR-3) axis and lymphangiogenesis, regional lymph node metastasis and clinicopathological ...
Asahina, Izumi, Takahashi, Hidenori, Shiraishi, Takeshi, Umeda, Masahiro, Yanamoto, Souichi, Yamada, Shin-Ichi, Matsushita, Yuki, Imayama, Naomi, Naruse, Tomofumi, Yamada, Shin‑Ichi, Ikeda, Hisazumi, Fujita, Shuichi, Ikeda, Tohru   +12 more
core   +1 more source

Prognostic Value of Podoplanin in Various Tumors

Technology in Cancer Research & Treatment, 2021
Background: The prognostic significance of podoplanin (PDPN) in tumor cells for cancer patients’ survival remains controversial. Therefore, we performed this meta-analysis to clarify the relationship between the podoplanin-positive tumor cells and cancer
Xiaohang Wang PhD, Xueying Wang MS, Vladmir Carvalho PhD, Qianqian Wang MS, Tingting Li MS, Jinbang Wang PhD, Yang Chen PhD, Chengming Ni PhD, Subo Liu BS, Jiaxin Zhang MS   +9 more
doaj   +1 more source

Tumor lymphangiogenesis and metastasis to lymph nodes induced by cancer cell expression of podoplanin

, 2010
The membrane glycoprotein podoplanin is expressed by several types of human cancers and might be associated with their malignant progression. Its exact biological function and molecular targets are unclear, however.
Moch, H, Gruber, S, Hegyi, Ivan, Albinger-Hegyi, Andrea, Detmar, Michael, Andrea Albinger-Hegyi, Ivan Hegyi, Leah N. Cueni, Silke Gruber, Albinger-Hegyi, A, Detmar, M, Rainer Kunstfeld, Cueni, Leah N, Kunstfeld, Rainer, Jay W. Shin, Cueni, L N, Shin, Jay W, Moch, Holger, Kunstfeld, R, Shin, J W, Gruber, Silke, Michael Detmar, Hegyi, I, Holger Moch   +23 more
core   +1 more source

Podoplanin-positive cells are a hallmark of encapsulating peritoneal sclerosis [PDF]

, 2010
BACKGROUND: Encapsulating peritoneal sclerosis (EPS) and simple peritoneal sclerosis are important complications of long-term peritoneal dialysis (PD). Podoplanin is expressed by mesothelial cells and lymphatic vessels, which are involved in inflammatory
Wüthrich, Rudolf P; https://orcid.org/, Ziegler, Urs; https://orcid.org/, F. Reimold, Biegger, Dagmar, I. Edenhofer, N. Braun, P. Fritz, Gaspert, Ariana, D. M. Alscher, B. Bode-Lesniewska, Segerer, Stephan; https://orcid.org/, M. Kimmel, Reimold, Fabian, D. Biegger, R. P. Wuthrich, U. Ziegler, S. Segerer, Braun, Niko, Alscher, Dominik M, Kimmel, Martin, Fritz, Peter; https://orcid.org/, Bode-Lesniewska, Beata; https://orcid.org/, Edenhofer, Ilka, A. Gaspert   +23 more
core   +1 more source

Prognostic value of podoplanin expression in intratumoral stroma and neoplastic cells of uterine cervical carcinomas

Clinics, 2010
OBJECTIVE: To investigate the clinicopathological significance of podoplanin expression in the intratumoral stroma and neoplastic cells of early stage uterine cervical cancer.
Filomena M Carvalho, Fabricia L Zaganelli, Bernardo G L Almeida, Joao Carlos Sampaio Goes, Edmund C Baracat, Jesus P Carvalho   +5 more
doaj   +1 more source

Podoplanin-Positive Fibroblasts Enhance Lung Adenocarcinoma Tumor Formation: Podoplanin in Fibroblast Functions for Tumor Progression

, 2011
During the metastatic process, cancer cells interact with vascular adventitial fibroblasts (VAF), which are the main components of the outermost connective tissue layer of blood vessels.
Takashi Ito, Yoichi Ohtaki, Kanji Nagai, Ayuko Hoshino, Genichiro Ishii, Hiroki Sasaki, Atsushi Ochiai, Kazuhiko Aoyagi   +7 more
core   +1 more source

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Phenotypically heterogeneous podoplanin-expressing cell populations are associated with the lymphatic vessel growth and fibrogenic responses in the acutely and chronically infarcted myocardium.

PLoS ONE, 2017
Cardiac lymphatic vasculature undergoes substantial expansion in response to myocardial infarction (MI). However, there is limited information on the cellular mechanisms mediating post-MI lymphangiogenesis and accompanying fibrosis in the infarcted adult
Maria Cimini, Antonio Cannatá, Gianandrea Pasquinelli, Marcello Rota, Polina Goichberg   +4 more
doaj   +1 more source

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

Developmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane, Angelina Almiroudis, Kaitlyn E. Donnelly, Robert S. Haltiwanger, Bernadette C. Holdener   +4 more
wiley   +1 more source