Results 61 to 70 of about 24,295 (222)

Patient‐Derived Neurons Exhibit α‐Synuclein Pathology and Previously Unrecognized Major Histocompatibility Complex Class I Elevation in Mitochondrial Membrane Protein–Associated Neurodegeneration

Movement Disorders, Volume 40, Issue 12, Page 2811-2818, December 2025.
Abstract Background Mitochondrial membrane protein–associated neurodegeneration (MPAN) from the neurodegeneration with brain iron accumulation (NBIA) family is a rare neurodegenerative disease marked by α‐synuclein aggregation, brain iron accumulation, and midbrain dopaminergic neuron degeneration.
Leonie M. Heger, Leonie Kertess, Clara Kaufhold, Francesco Gubinelli, Aida Cardona‐Alberich, Gamze Özata, Stephan A. Müller, Sarah K. Tschirner, Oliver Stehling, Martina Schifferer, Camille Peron, Valeria Tiranti, Roland Lill, Arcangela Iuso, Luigi Zecca, Michael Strupp, Wolfgang Oertel, Stefan F. Lichtenthaler, Lena F. Burbulla   +18 more
wiley   +1 more source

Trans-Planckian Physics and Inflationary Cosmology [PDF]

, 2002
Due to the quasi-exponential red-shifting which occurs during an inflationary period in the very early Universe, wavelengths which at the present time correspond to cosmological lengths are in general sub-Planckian during the early stages of inflation ...
Brandenberger, Robert H.
core   +2 more sources

Dual Clumped Isotope (Δ47, Δ48) Values for Calcite Grown at Varying pH and Carbonic Anhydrase Concentrations Constrain Equilibrium and Kinetic Isotope Effects

Geochemistry, Geophysics, Geosystems, Volume 26, Issue 12, December 2025.
Abstract This study explores the isotopologues m/z 47 (13C18O16O, denoted Δ47) and m/z 48 (12C18O2, denoted Δ48) in CO2 derived from carbonate minerals, focusing on their temperature dependency, kinetic isotope effects, and distinct reaction pathways. By conducting experiments at four temperatures (5°C, 10°C, 15°C, and 25°C) using the enzyme carbonic ...
Jamie Lucarelli, Bettina Purgstaller, Zeeshan Parvez, James M. Watkins, Robert A. Eagle, Martin Dietzel, Aradhna Tripati   +6 more
wiley   +1 more source

Method Overview for Discovering ATE1 Substrates and their Arginylation Sites

ChemBioChem, Volume 26, Issue 23, November 27, 2025.
Arginylation is a decades‐old post‐translational modification but is inherently difficult to study. A plurality of methods have been developed and deployed to uncover the biology and substrates of this modification. This review covers the history, major advancements, and substrates discovered over the course of six decades.
Richard M. Searfoss, Benjamin A. Garcia, Zongtao Lin   +2 more
wiley   +1 more source

Dynamical fat link fermions [PDF]

, 2004
The use of APE smearing or other blocking techniques in fermion actions can provide many advantages. There are many variants of these fat link actions in lattice QCD currently, such as FLIC fermions.
Alexandru, Anthony G. Williams, APE, Bietenholz, CSSM Lattice, DeGrand, Derek B. Leinweber, Duane, Falcioni, Hasenfratz, Kamleh, Kovacs, Leinweber, Liang, MILC, Morningstar, Stephenson, Waseem Kamleh   +17 more
core   +3 more sources

Carlo V novello Ercole: la Rotella D63 della Real Armería di Madrid

Gilgameš, 2016
In the collections of the Real Armería of Madrid it is conserved a shield known as Plus Ultra or Apotheosis of Charles V. The young emperor Charles V is compared, until 1516, to the mythical hero Hercules, who placed two columns at the edge of the known world. Starting from 1530 this identification is accompanied with a new image of the emperor.
openaire   +1 more source

Impacts of Bulk Microphysics Scheme Structural Choices on Simulations of Rain Initiation Through Drop Coalescence

Journal of Advances in Modeling Earth Systems, Volume 17, Issue 11, November 2025.
Abstract This study examines how different structural choices in bulk microphysics schemes impact the simulation of warm rain initiation. A single liquid category (SLC) approach prognosing up to four moments of a single drop size distribution (DSD) is compared to the traditional two‐category, two‐moment approach with separate DSDs for cloud and rain ...
Hugh Morrison, Po‐Lun Ma, Andrew Geiss, Adele L. Igel, Arthur Z. Hu, Marcus van Lier‐Walqui   +5 more
wiley   +1 more source

Ex post approaches to prioritarianism and sufficientarianism

Theoretical Economics, Volume 20, Issue 4, Page 1367-1410, November 2025.
Although sufficientarianism has been gaining interest as a theory of distributive justice in recent years, it has not been examined in the presence of risk. We propose an ex post approach to sufficientarianism that has a strong link to ex post prioritarianism.
Matthew D. Adler, Walter Bossert, Susumu Cato, Kohei Kamaga   +3 more
wiley   +1 more source

Age Constraints on Brane Models of Dark Energy [PDF]

, 2002
Inspired by recent developments in particle physics, the so-called brane world cosmology seems to provide an alternative explanation for the present dark energy problem.
Abha Dev, C. Deffayet, C. Deffayet, C. Deffayet, C. van de Bruck, C.J. Hogan, C.J. Hogan, D.J.H. Chung, Deepak Jain, G. Dvali, G. Dvali, G. Dvali, G. Dvali, G.D. Starkman, H. Kodama, H. Spinrard, J. Dunlop, J. Khoury, J. S. Alcaniz, J.A.S. Lima, J.S. Alcaniz, J.S. Alcaniz, K. Koyama, L. Randall, L. Randall, P.P. Avelino, R. Dick, R. Dick, R.H. Brandenberger, S.-H. Henry Tye, S.C. Davis, T. Shiromizu, W. Fischler, W.L. Freedman   +33 more
core   +2 more sources

Tacrolimus Concentration in Pediatric Compounded Suspensions Under Conditions Mimicking Real‐Life Use

Pediatric Transplantation, Volume 29, Issue 6, September 2025.
ABSTRACT Background Tacrolimus is an immunosuppressant drug with a narrow therapeutic index used to treat children following solid organ transplantation as well as those with other immune‐mediated conditions. While tacrolimus exists as a child‐friendly commercially prepared formulation in many countries, such formulation adapted to children's needs is ...
Émilie Kate Landry, Raphaël Kraus, Feriel Djebbar, Julie Autmizguine, Sophie Bérubé, Denis Lebel, Catherine Litalien   +6 more
wiley   +1 more source