Misidentification of Putative Medullary Thyroid Cancer Cell Lines RO-H85-1 and RO-D81-1 [PDF]
In 2008, the JCEM published a landmark paper showing redundancy or misidentification of almost 50% of a panel of 40 commonly used differentiated and anaplastic thyroid cancer cell lines (1); this finding had significant implications for the thyroid cancer research field (2).
Tikva, Dadon +2 more
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Abstract A statistical-thermodynamic model for binary nonstoichiometric A 5 B 3 with D8 1 -structure has been established on the basis of the grand canonical ensemble. In the model the average chemical potentials according to the composition and a new extra equation as a boundary condition are proposed for more accuracy and free experimental data ...
Shang, JX, Zhang, Y, Chen, Y
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SURFS and AlphaFold Reveal Ribosome Footprint Shift Caused by EF-Tu D81 Mutation
SummaryProtein synthesis relies on accurate mRNA decoding by tRNA, a process guided by EF-Tu. We investigated how mutations at a conserved residue, aspartate 81, affect EF-Tu function using GTPase assays, AlphaFold modeling, and quantum-sensing-based super-resolution force spectroscopy (SURFS).
Yi Zeng +3 more
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Anti-hemagglutinin monomeric nanobody provides prophylactic immunity against H1 subtype influenza A viruses. [PDF]
Influenza viruses constitute a major threat to human health globally. The viral surface glycoprotein hemagglutinin (HA) is the immunodominant antigen, contains the site for binding to the cellular receptor (RBS), and it is the major target of ...
Barbieri ES +13 more
europepmc +2 more sources
D81. Gene Expression as Biomarkers of Tissue Viability in Ex Vivo Normothermic Limb Perfusion (EVNLP) [PDF]
Abigail Meyers, BS +5 more
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D81. Isolated Nonsyndromic Lambdoid Synostosis: A Single Center’s 30-year Experience with 31 Patients [PDF]
Jinggang J. Ng, MA +8 more
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D81. A Comparative Analysis of One-stage Versus Two-stage Facial Feminization Surgery: Clinical Outcomes, Complication Rates, and Cost-effectiveness in a Retrospective Cohort Study [PDF]
Anh-Tho Antoinette T. Nguyen, BA +3 more
openaire +3 more sources
Mean–variance relationship and uncertainty [PDF]
This study investigates the impact of uncertainty on the mean-variance relationship. We find that the stock market's expected excess return is positively related to the market's conditional variances and implied variance during low uncertainty periods ...
Jun Sik Kim
doaj +1 more source
Economic policy uncertainty and overinvestment: evidence from Korea [PDF]
The authors show that there is a negative relationship between economic policy uncertainty (EPU) and firm overinvestment using Korean data from 2007 to 2016. Since Jensen (1986) shows that a firm's free cash flow is an important factor of overinvestment,
Wenwen Jiang, Hwa-Sung Kim
doaj +1 more source
One-criterion decision making under uncertainty (1-DM/U) is related to situations in which the decision maker (DM) evaluates the alternatives on the basis of one objective, but e.g.
Gaspars-Wieloch Helena
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