Results 1 to 10 of about 24,286 (164)

Natural Products Inhibit Bacterial Growth and Modulate Quorum-Sensing Systems Las and Rhl in Pseudomonas aeruginosa PA14. [PDF]

Chem Biodivers
ABSTRACT Quorum sensing (QS) is a bacterial cell communication system in Pseudomonas aeruginosa, which regulates the production of several virulence factors, including pyocyanin, exoproteases, and biofilm formation. Natural products (NPs) have demonstrated their ability to control QS in different bacteria. This work evaluated the antimicrobial and anti‐
Martínez-Rodríguez OP, García-Contreras R, Aguayo-Ortiz R, Yeverino IR, Fajardo-Hernández CA, Patiño AD, Hernández Pérez HA, Hernández-Garnica M, Figueroa M.   +8 more
europepmc   +2 more sources

Conformational Trajectory of the Molecular Chameleon Grazoprevir From Formulation to Target-Bound. [PDF]

Chemistry
ABSTRACT Macrocycles represent a promising class of beyond‐rule‐of‐5 (bRo5) therapeutics, capable of targeting proteins traditionally considered undruggable by conventional small molecules. Macrocycles exhibit intrinsic flexibility and often display a “chameleon‐like” ability to adapt to their environment, thereby enhancing their oral bioavailability ...
Wieske LHE, Bu G, Erdélyi M, Kihlberg J, Gonen T, Danelius ER.   +5 more
europepmc   +2 more sources

D81. Gene Expression as Biomarkers of Tissue Viability in Ex Vivo Normothermic Limb Perfusion (EVNLP) [PDF]

Plastic and Reconstructive Surgery - Global Open, 2023
Abigail Meyers, BS, Varun Kopparthy, PhD, Payam Sadeghi, MD, Francis Papay, MD, Antonio Rampazzo, MD, PhD, Bahar Bassiri Gharb, MD, PhD   +5 more
openaire   +3 more sources

D81. A Comparative Analysis of One-stage Versus Two-stage Facial Feminization Surgery: Clinical Outcomes, Complication Rates, and Cost-effectiveness in a Retrospective Cohort Study [PDF]

Plastic and Reconstructive Surgery - Global Open
Anh-Tho Antoinette T. Nguyen, BA, Kasey W. Matabele, MD, Clinton Morrison, MD, Jonathan Leckenby, MBBS   +3 more
openaire   +3 more sources

D81. Isolated Nonsyndromic Lambdoid Synostosis: A Single Center’s 30-year Experience with 31 Patients [PDF]

Plastic and Reconstructive Surgery - Global Open
Jinggang J. Ng, MA, Ashley E. Chang, BA, Benjamin B. Massenburg, MD, Dominic J. Romeo, MA, Meagan Wu, MA, Jessica Blum, MD, Jordan W. Swanson, MD, Jesse A. Taylor, MD, Scott P. Bartlett, MD   +8 more
openaire   +3 more sources

Mean–variance relationship and uncertainty [PDF]

Seonmul yeongu, 2022
This study investigates the impact of uncertainty on the mean-variance relationship. We find that the stock market's expected excess return is positively related to the market's conditional variances and implied variance during low uncertainty periods ...
Jun Sik Kim
doaj   +1 more source

Economic policy uncertainty and overinvestment: evidence from Korea [PDF]

Seonmul yeongu, 2021
The authors show that there is a negative relationship between economic policy uncertainty (EPU) and firm overinvestment using Korean data from 2007 to 2016. Since Jensen (1986) shows that a firm's free cash flow is an important factor of overinvestment,
Wenwen Jiang, Hwa-Sung Kim
doaj   +1 more source

On some analogies between one-criterion decision making under uncertainty and multi-criteria decision making under certainty

Economics and Business Review, 2021
One-criterion decision making under uncertainty (1-DM/U) is related to situations in which the decision maker (DM) evaluates the alternatives on the basis of one objective, but e.g.
Gaspars-Wieloch Helena
doaj   +1 more source

Global Economic Uncertainties and Exchange Rate Management in Africa: A Panel Study

Acta Universitatis Sapientiae: Economics and Business, 2022
This study investigates the effects of global economic uncertainties on exchange rate management in Africa from 1990 to 2021. Employing the quantile regression technique, findings show that both global and domestic economic uncertainties have significant
Adedokun Adeniyi J., Falayi Olabusuyi R., Adeyemi Francis O., Kumeka Terver T.   +3 more
doaj   +1 more source

Does Entrepreneurial Risk-Taking Affect the Business Performance of Micro-Enterprises? Evidence from Skikda in Algeria

Naše Gospodarstvo, 2022
According to several previous studies, entrepreneurial risk-taking is an important aspect that can lead to prospective business opportunities, hence improving entrepreneurial outcomes such as enterprise performance.
Messikh Ayoub
doaj   +1 more source