Results 51 to 60 of about 24,286 (164)

Exploration of questionable backbone conformations in crystallographic structure models using a structural alphabet

open access: yesActa Crystallographica Section D, Volume 81, Issue 12, Page 734-757, December 2025.
We present a protocol to detect and characterize questionable backbone conformations in X‐ray protein structure models. These conformations may arise from artifacts related to the crystallization process or from errors introduced during model building and refinement.
Clémence Sarrau   +5 more
wiley   +1 more source

Vector and tensor perturbations in Horava-Lifshitz cosmology

open access: yes, 2010
We study cosmological vector and tensor perturbations in Horava-Lifshitz gravity, adopting the most general Sotiriou-Visser-Weinfurtner generalization without the detailed balance but with projectability condition.
Anzhong Wang   +4 more
core   +1 more source

On Models of New Physics for the Tevatron Top A_FB [PDF]

open access: yes, 2011
CDF has observed a top forward-backward asymmetry discrepant with the Standard Model prediction at 3.4 \sigma. We analyze models that could generate the asymmetry, including flavor-violating W's, horizontal Z'_Hs, triplet and sextet diquarks, and ...
Gresham, Moira I.   +2 more
core   +3 more sources

Polo‐like kinase 1–inhibitor co‐complex structures via the surface‐entropy reduction approach and a DARPin‐assisted approach

open access: yesActa Crystallographica Section D, Volume 81, Issue 12, Page 718-733, December 2025.
A surface‐entropy reduction approach for human Polo‐like kinase 1 (PLK1) enabled a reproducible and robust crystallization system for this cancer drug target. Co‐crystal structures with representatives of three different small‐molecule inhibitor classes were elucidated.
Uwe Eberspaecher   +7 more
wiley   +1 more source

Xtricorder: a likelihood‐enhanced self‐rotation function and application to a machine learning‐enhanced Matthews prediction of asymmetric unit copy number

open access: yesActa Crystallographica Section D, Volume 81, Issue 12, Page 678-692, December 2025.
Xtricorder is a tool for analysing crystallographic data, featuring a likelihood‐enhanced self‐rotation function and a novel `composite‐section diagram' thereof, which aids interpretation and enables a machine learning‐enhanced prediction of asymmetric unit content.Analysis of crystallographic diffraction data after collection and integration but ...
Airlie J. McCoy, Randy J. Read
wiley   +1 more source

Completion of partial structures using Patterson maps with the CrysFormer machine‐learning model

open access: yesActa Crystallographica Section D, Volume 81, Issue 12, Page 668-677, December 2025.
We integrate existing machine learning‐based protein structure‐prediction methods with X‐ray crystallography by completing partial structures derived from AlphaFold predictions and the corresponding Patterson map information. The CrysFormer results are promising when applied to an initial data set of 15‐residue fragments in P21 unit cells.Protein ...
Tom Pan   +4 more
wiley   +1 more source

On mass limit for chiral color symmetry $G'$-boson from Tevatron data on $t \bar{t}$ production

open access: yes, 2010
The contributions of $G'$-boson predicted by the chiral color symmetry of quarks to the cross section $\sigma_{t\bar{t}}$ and to the forward-backward asymmetry $A_{\rm FB}^{p \bar p}$ of $t\bar{t}$ production at the Tevatron are calculated with account ...
Martynov, M. V., Smirnov, A. D.
core   +1 more source

Reconstructing biological molecules with help from video gamers

open access: yesActa Crystallographica Section D, Volume 81, Issue 11, Page 598-604, November 2025.
The results of the Foldit citizen science puzzles for crystallographic models and their integration into the PDB‐REDO databank are discussed.Foldit is a citizen science video game in which players tackle a variety of complex biochemistry puzzles. Here, we describe a new series of puzzles in which Foldit players improve the accuracy of models in the ...
Andreas C. Petrides   +4 more
wiley   +1 more source

Non-Gaussianity Consistency Relation for Multi-field Inflation

open access: yes, 2011
While detection of the "local form" bispectrum of primordial perturbations would rule out all single-field inflation models, multi-field models would still be allowed.
A. A. Starobinsky   +7 more
core   +1 more source

Cryo‐EM single‐particle analysis expanding towards increasingly native samples

open access: yesActa Crystallographica Section D, Volume 81, Issue 11, Page 587-597, November 2025.
Cryo‐EM single‐particle analysis has revolutionized structural biology by allowing high‐resolution analysis of large molecular assemblies that are not amenable to crystallography or NMR. Combination of this technology with innovative sample‐preparation protocols further expands the range of potential targets.The explosion of cryo‐electron microscopy ...
Jonas Moecking, Tzviya Zeev-Ben-Mordehai
wiley   +1 more source

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