Results 61 to 70 of about 19,034 (221)

Optimized bacterial expression of a synthetic BRIL antibody

Acta Crystallographica Section F, EarlyView.
Here, we document the generation of a T7 Express ΔcybC strain allowing contaminant‐free expression of the anti‐BRIL Fab BAG2. We also report the crystal structure of BAG2 in complex with native cytochrome b562, a complex arising from expression in canonical Escherichia coli strains.The use of monoclonal fragments antigen binding (Fabs) is a prevalent ...
Benjamin F. Cooper, Georgia L. Isom
wiley   +1 more source

Selective Root Canal Retreatment: A Scoping Review and Metasynthesis by Thematic Analysis

Australian Endodontic Journal, EarlyView.
ABSTRACT Selective root canal retreatment preserves well‐filled canals by treating only roots showing clinical or imaging evidence of failure, providing a minimally invasive alternative to conventional full retreatment. This scoping review, supported by metasynthesis through thematic analysis, synthesised clinical and imaging evidence in multirooted ...
José Evando da Silva‐Filho, Júlia Magalhães‐Saldanha, Ana Paula Caracas‐de‐Araújo, Zildenilson da Silva Sousa, Danielle Frota de Albuquerque, Eduardo Diogo Gurgel‐Filho   +5 more
wiley   +1 more source

Improving access to direct acting antivirals via a multimodal integrated care program in an addiction medicine clinic

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Injection drug use is a driver of hepatitis C virus (HCV) transmission, thus integrating HCV care into addiction care is likely necessary for HCV elimination. Here we describe how we integrated HCV care into our addiction medicine (AM) clinic and evaluate its effect on HCV treatment.
Arya Zandvakili, Joseph Rattenni, James Burton, Lakshmi Guduguntla, Marcus Osman, Sayeh Sabbagh, Stephan Arndt, Ben Miskle, Quanhathai Kaewpoowat, Michael Ohl, Andrea Weber, Alison Lynch   +11 more
wiley   +1 more source

The Expanding Role of Companion Diagnostics in Infectious Diseases: Lessons From Abacavir and Human Immunodeficiency Virus Care

iLABMED, EarlyView.
Yi‐Wei Tang, Eric von Hofe
wiley   +1 more source

Clinical Need and Research Investment for Liver Cancer in Australia

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Liver cancer incidence and mortality rates have been rising in comparison to other common cancers, but research funding has not been commensurate. ABSTRACT Aim This study aims to better understand factors driving the rising burden and costs of primary liver cancer (PLC) in Australia, identify key epidemiological trends, and ascertain investment in PLC ...
Romario Nguyen, Fatema Safri, Ankur Sharma, Jessica Howell, Stuart K. Roberts, Simone I. Strasser, Amany Zekry, Alan Wigg, Leon A. Adams, Michael Wallace, Golo Ahlenstiel, Eleonora Feletto, Karen Canfell, Tracey O'Brien, Jacob George, Liang Qiao   +15 more
wiley   +1 more source

Toxicokinetic modelling of the synthetic cannabinoid 5F‐MDMB‐P7AICA and its main metabolite in pigs following pulmonary administration

British Journal of Clinical Pharmacology, EarlyView.
Aims Since their emergence on the drug market, synthetic cannabinoids (SC) are still gaining increasing importance in forensic toxicology. The representatives of the so‐called new psychoactive substances have in common that they have not undergone preclinical safety studies. Hence, knowledge on toxicokinetic (TK) data is sparse.
Adrian A. Doerr, Christiane Dings, Omar Zaher, Frederike Nordmeier, Nadja Walle, Matthias W. Laschke, Michael D. Menger, Peter H. Schmidt, Markus R. Meyer, Thorsten Lehr, Nadine Schaefer   +10 more
wiley   +1 more source

Prevalence, conceptual distinctiveness, and cross‐sectional correlates of climate worry in Canadian adolescents

Child and Adolescent Mental Health, EarlyView.
Background As the impacts of the climate crisis escalate, adolescents face increasing threats to their health and well‐being. However, little is known about the extent to which young adolescents experience climate worry (both in its general affective response and its specific cognitive concerns) and whether it is distinguishable from generalized ...
Joanne L. Park, Audrey‐Ann Deneault, Brae Anne McArthur, Suzanne Tough, Sheri Madigan   +4 more
wiley   +1 more source

Water Management of Arabica Coffee Seedlings Cultivated with a Hydroretentive Polymer

Agronomy
The production of high-quality coffee seedlings is essential to meet the demands of the coffee sector, requiring more efficient and sustainable water management practices.
Mateus Oliveira Silva, Vanessa Reniele Souza de Arruda, Francisco Raylan Sousa Barbosa, Michel Wakim Mendes Firmino, Adriene Woods Pedrosa, Fernando França da Cunha   +5 more
doaj   +1 more source

HCV-Therapie durch DAA vereinfacht [PDF]

CME, 2017
Zahlreiche Praparate vom DAA-Typ (Direct-acting antiviral drugs) eroffnen bei HIV-Infizierten, die auch HCV-positiv sind, inzwischen die Moglichkeit der Interferon-freien Behandlung.
openaire   +1 more source

Embodied practice in a disembodied time: How the COVID‐19 pandemic shaped direct work with children and young people

Child &Family Social Work, EarlyView.
Abstract The COVID‐19 pandemic and related restrictions imposed in the UK had a significant impact on social work practice with children and young people. As has been widely reported, practitioners were deprived of multisensory information in their assessments and of opportunities to connect with children.
Heather Ellis, Ariane Critchley
wiley   +1 more source