Results 51 to 60 of about 14,647 (219)
Case Reports in Critical Care, 2015 The oral anticoagulant dabigatran etexilate can be a challenge when patients need acute surgery. Sepsis and acute renal failure exacerbate the anticoagulant effect.
Rikke Ebenhard Højland +2 more
doaj +1 more source
Dabigatran versus Warfarin for the Treatment of Pediatric Thromboembolism: A Pilot Randomized Trial [PDF]
Pharmaceutical Sciences, 2020 Background: Venous thromboembolism (VTE) is still a problematic situation in children. Drugs like warfarin, enoxaparin, and heparin are current standard of care in childhood VTE. This study was designed to compare the efficacy of warfarin with dabigatran
Aziz Eghbali +5 more
doaj +1 more source
New safety standards for anticoagulant therapy in the treatment of atrial fibrillation
Российский кардиологический журнал, 2018 The review article study the safety and efficacy of using direct acting oral anticoagulants: thrombin inhibitor dabigatran etexilate and inhibitors Xa of the blood clotting factor apixaban, rivaroxaban and edoxaban compared with the vitamin K antagonist ...
E. I. Baranova
doaj +1 more source
Российский кардиологический журнал, 2019 The review discusses the problem of patient-oriented choice of anticoagulants for nonvalvular atrial fibrillation (AF). The efficacy and safety profile of dabigatran etexilate and a group of patients with advantage of dabigatran application: patients ...
E. I. Baranova, Zhanna Kobalava
doaj +1 more source
The Pharmacology and Therapeutic Use of Dabigatran Etexilate [PDF]
The Journal of Clinical Pharmacology, 2013 AbstractDabigatran etexilate is an oral prodrug of dabigatran, a direct thrombin inhibitor, that provides the first available oral anticoagulant alternative to warfarin for reducing the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (AF).
openaire +3 more sources
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2014 The results of application of dabigatran etexilate in treatment of 56 patients aged 60 to 89 with closed diaphyseal fractures of femur and tibia undergone intramedullary osteosynthesis were studied. The patients were divided into 2 groups.
A. K. Dulaev, A. N. Tsed, I. G. Dzhusoev
doaj +1 more source
Рациональная фармакотерапия в кардиологии, 2015 Disadvantages of vitamin K antagonist warfarin and the benefits of new anticoagulants, including dabigatran etexilate, in the stroke prevention in patients with atrial fibrillation are considered.
E. D. Kosmacheva +6 more
doaj +3 more sources
Frontiers in Pharmacology, 2023 Background: The most favorable gastrointestinal (GI) bleeding safety profile among different types of direct oral anticoagulants (DOACs) remains controversial. This meta-analysis includes the latest studies and aims to compare GI bleeding risk associated
Xiuehui Chen +5 more
doaj +1 more source
Dose tailoring of dabigatran etexilate: obvious or excessive? [PDF]
Expert Opinion on Drug Safety, 2015 Dabigatran etexilate is used for preventing blood clots and tends to replace older anticoagulants in many of their indications. However, the 'one dose fits all' policy is subject to criticism. Recent findings assert the anxiety of the scientific community concerning the pharmacokinetic properties of dabigatran etexilate, that is, an important ...
Douxfils, Jonathan +2 more
openaire +4 more sources
Neck‐vein thrombosis during spaceflight
British Journal of Clinical Pharmacology, EarlyView.Spaceflight imposes unique environmental challenges, including weightlessness, increased radiation exposure and confinement, which can lead to unexpected health effects. One such example is neck‐vein thrombosis, a condition rarely seen on Earth without predisposing factors such as venous catheters or infections.
Ulrich Limper, Jens Jordan
wiley +1 more source