Results 71 to 80 of about 1,429 (166)

Convergent hemostatic disruption by distinct venom architectures in Bothrops spp. and Daboia russelii

open access: yes
Snake venoms from the genera Bothrops and Daboia are well known for inducing severe hemostatic disturbances and are responsible for significant clinical manifestations associated with snakebite envenomation in different regions worldwide.
Junior, Rui Seabra Ferreira   +8 more
core   +5 more sources

Assessment of quality and pre-clinical efficacy of a newly developed polyvalent antivenom against the medically important snakes of Sri Lanka

open access: yesScientific Reports, 2021
Snake envenomation is a severe problem in Sri Lanka (SL) and Indian polyvalent antivenom (PAV) is mostly used for treating snakebite albeit due to geographical variation in venom composition, Indian PAV shows poor efficacy in neutralizing the lethality ...
Aparup Patra   +5 more
doaj   +1 more source

Medicinal Plants and Lead Phytomolecules as Immunomodulators: An Updated Review

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
All therapeutic interventions aimed at modulating the immune response to pathogens, self‐antigens, carcinogens, or xenogeneic antigens are referred to as immunomodulation, which either prevents hyperactivation or restores the appropriate response of the immune system.
Gurdeep Singh   +3 more
wiley   +1 more source

From birth to bite: the evolutionary ecology of India's medically most important snake venoms

open access: yesBMC Biology
Background Snake venoms can exhibit remarkable inter- and intraspecific variation. While diverse ecological and environmental factors are theorised to explain this variation, only a handful of studies have attempted to unravel their precise roles.
R. R. Senji Laxme   +4 more
doaj   +1 more source

Unmasking the Desert Phantom: Genetic Evidence Does Not Support the Validity of the Enigmatic Boehme's Horned Viper

open access: yesZoologica Scripta, Volume 54, Issue 6, Page 817-822, November 2025.
ABSTRACT The viperid genus Cerastes contains four desert‐adapted species distributed throughout the Saharo‐Arabian arid belt that are typically associated with loose sands. Cerastes boehmei is restricted to one locality in Tunisia and is known only from the holotype.
Vojtěch Waldhauser   +8 more
wiley   +1 more source

Biochemical and pharmacological properties of a new thrombin-like serine protease (Russelobin) from the venom of Russell's Viper (Daboia russelii russelii) and assessment of its therapeutic potential

open access: yes, 2013
Background: Snake venoms are rich sources of bioactive molecules, and several venom-derived proteins have entered clinical trials for use in ischemic disorders; however, late-stage failure of a recent drug candidate due to low in vivo efficacy ...
Mukherjee, Ashis K.   +1 more
core   +1 more source

In Vitro Immunological Cross-Reactivity of Thai Polyvalent and Monovalent Antivenoms with Asian Viper Venoms

open access: yesToxins, 2020
The intravenous administration of polyclonal antibodies known as antivenom is the only effective treatment for snakebite envenomed victims, but because of inter-specific variation in the toxic components of snake venoms, these therapies have variable ...
Janeyuth Chaisakul   +6 more
doaj   +1 more source

Understanding Suitable Habitats and Anthropogenic Mortality Risks for King Cobras in Nepal

open access: yesEcology and Evolution, Volume 15, Issue 9, September 2025.
The king cobra (Ophiophagus hannah), a vulnerable species, faces significant habitat loss and mortality risks in Nepal. Using ensemble modeling with 553 occurrence records, this study identified 23,702.62 km2 of suitable habitat, projecting up to 22% habitat loss by 2050 under SSP2‐4.5 climate scenarios.
Rishi Baral   +11 more
wiley   +1 more source

One Bite, Two Severe Envenomations Despite Antivenom Therapy: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT This case report describes a 12‐year‐old child who was bitten by a cobra and developed two distinct systemic neurotoxic episodes, 19 h apart, along with severe local envenoming, despite receiving appropriate treatment with antivenom and making a full recovery.
Ravi Shukla   +4 more
wiley   +1 more source

Development of renal function abnormalities following bites by Russell's vipers (Daboia russelii siamensis) in Myanmar

open access: yesTransactions of the Royal Society of Tropical Medicine and Hygiene, 1991
Renal function was monitored in 24 patients with systemic envenoming following proven Russell's viper bite. In all patients, blood clotted within 20 min on admission. In 15 cases severe defibrination (systemic envenoming) developed during the next 3-5 d.
Thein-Than   +6 more
openaire   +2 more sources

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