Results 81 to 90 of about 1,429 (166)

Unraveling the molecular basis of snake venom nerve growth factor: human TrkA recognition through molecular dynamics simulation and comparison with human nerve growth factor

Frontiers in Bioinformatics
IntroductionNeurodegenerative diseases pose significant challenges owing to the limited number of effective therapies. Nerve growth factor (NGF) plays a crucial role in neuronal survival and differentiation through tropomyosin receptor kinase A (TrkA ...
Shrudhi Devi, Gurunathan Jayaraman
doaj   +1 more source

Biochemical and Biological Profiles of Bangladeshi Russell’s Viper Snake Venom and Neutralizing Efficacy by Indian VINS Polyvalent Antivenom

Journal of Toxicology, Volume 2025, Issue 1, 2025.
The Russell’s viper (Daboia russelii) has recently become a significant threat to human life in Bangladesh. Given its wide distribution across South Asia, the venom characteristics and lethality can vary by region with different toxicological properties.
Rubait Hasan, Hasanuzzaman Manik, Md Ataur Rahman, Jamiatul Husna Shathi, Md Tariqul Islam, Mohammad Shahangir Biswas, Kazi Md. Faisal Hoque, Phuping Sucharitakul   +7 more
wiley   +1 more source

A major phospholipase A2 from Daboia russelii russelii venom shows potent anticoagulant action via thrombin inhibition and binding with plasma phospholipids

, 2014
This is the first report on antithrombin effects of a phospholipase A2 (RVAPLA2) purified from venom of Daboia russelii russelii. The N-terminal sequence as well as in-gel tryptic digested peptides of RVAPLA2 showed significant homology with PLA2s from ...
Mukherjee, Ashis. K.
core   +1 more source

Snake venom toxins: Potential anticancer therapeutics

Journal of Applied Toxicology, Volume 44, Issue 5, Page 666-685, May 2024.
Abstract Snake venom contains a cocktail of compounds dominated by proteins and peptides, which make up the toxin. The toxin components of snake venom attack several targets in the human body including the neuromuscular system, kidney and blood coagulation system and cause pathologies. As such, the venom toxins can be managed and used for the treatment
Benedict C. Offor, Lizelle A. Piater
wiley   +1 more source

Ketjukyyn (Daboia russelii) myrkyn hyödyntäminen syöpätutkimuksessa

, 2023
Tiivistelmä. Rintasyöpä on naisten yleisin syöpätyyppi. Vuonna 2018 siihen sairastui 2,1 miljoonaa naista ja maailmanlaajuisesti raportoitiin 627 000 rintasyövästä johtuvaa kuolemaa. Rintasyöpiä luokitellaan useisiin eri tyyppeihin ja sitä voidaan hoitaa leikkauksilla sekä säde- ja lääkehoidoilla.
openaire   +1 more source

Venomous snakebites: Exploring social barriers and opportunities for the adoption of prevention measures

Conservation Science and Practice, Volume 6, Issue 2, February 2024.
The study investigates strategies for reducing negative interactions between humans and venomous snakes. Using a health belief model framework, the research examines factors influencing the adoption of snakebite prevention measures in a high snakebite‐risk area of southern India.
Harrison Carter, Xavier Glaudas, Romulus Whitaker, Gnaneswar Chandrasekharun, Kimberley Hockings, Ana Nuno   +5 more
wiley   +1 more source

Dataset for "Clinical and pharmacological investigation of myotoxicity in Sri Lankan Russell's viper (Daboia russelii) envenoming"

, 2016
All clinical and experimental data for the journal article "Clinical and pharmacological investigation of myotoxicity in Sri Lankan Russell's viper (Daboia russelii ...
Christopher Johnston (2172493), Geoffrey K. Isbister (8281572), Ian Smith (20961), Oded Kleifeld (689464), Wayne C. Hodgson (412268), Anaja Silva (21273716), Daniela Kneisz (3375098), Kalana Maduwage (527730), Sisira Siribaddana (319687), Sanjaya Kuruppu (3375095), Nicholas A. Buckley (7294397)   +10 more
core  

Phylovenomics of Daboia russelii across the Indian subcontinent. Bioactivities and comparative in vivo neutralization and in vitro third-generation antivenomics of antivenoms against venoms from India, Bangladesh and Sri Lanka [PDF]

, 2019
17 páginas, 6 figuras, 3 tablasRussell's viper (Daboia russelii) is, together with Naja naja, Bungarus caeruleus and Echis carinatus, a member of the medically important ‘Big Four’ species responsible for causing a large number of morbidity and mortality
Sanz, Libia, Wahed Chowdhuryd, Mohammad Abdul, Kuch, Ulrich, Pla Ferrer, Davinia, Villalta Arrieta, Mauren, León Montero, Guillermo, Quesada Bernat, Sarai, Baal, Joshua, Gutiérrez, José María, Calvete Chornet, Juan José   +9 more
core   +1 more source

Capillary leak syndrome induced by the venoms of Russell\u27s Vipers (Daboia russelii and Daboia siamensis) from eight locales and neutralization of the differential toxicity by three snake antivenoms

, 2021
Snakebite envenomation caused by the Western and Eastern Russell\u27s Vipers (Daboia russelii and Daboia siamensis) may potentially induce capillary leak syndrome (CLS), while the use of antivenom in treating this has not been well examined.
Tan, Kae Yi, Tan, Choo Hock, Lingam, Thava Malar Changra   +2 more
core   +1 more source

Causes, Complications and Short‐Term Outcome of Acute Kidney Injury in a Resource‐Limited Setting

International Journal of Nephrology, Volume 2024, Issue 1, 2024.
Aims: The outcome of acute kidney injury (AKI) depends on causes, patient factors and care received. We studied the causes, complications and 90‐day outcomes of patients with AKI at a tertiary referral centre in Sri Lanka. Methods: Patients aged 18 years or older with AKI referred to nephrology services were analysed retrospectively.
Nalaka Herath, Shamila De Silva, Prasitha Liyanage, Sameera Kumara, Suganthika Devi, Vajira Abeysekara, Ruvini Mallawarachi, Suharshi Perera, Iresha Karunathilaka, Sameera Samarasinghe, Kosala Weerakoon, Anil K. Agarwal   +11 more
wiley   +1 more source