Results 201 to 210 of about 18,109 (249)

Dietary soy protein reverses obesity-induced liver steatosis and alters fecal microbial composition independent of isoflavone level. [PDF]

Front Nutr
Hakkak R, Korourian S, Li W, Spray B, Twaddle NC, Randolph CE, Børsheim E, Robeson Ii MS.   +7 more
europepmc   +1 more source

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Daidzein ameliorates diabetic retinopathy in experimental animals.

Life Sciences, 2020
The present study was designed to check the effect of daidzein in the management of diabetic retinopathy.Streptozotocin at dose 55 mg/kg was used for inducing diabetes in rats. After 28 days of diabetic induction, animals were treated with daidzein at dose 25, 50, and 100 mg/kg for the next 28 days.
A. Laddha, Yogesh A. Kulkarni
semanticscholar   +3 more sources

Pharmacokinetics, pharmacodynamics, toxicity, and formulations of daidzein: An important isoflavone

Phytotherapy Research, 2023
Daidzein, 7‐hydroxy‐3‐(4‐hydroxyphenyl)‐4H‐chromen‐4‐one is a naturally occurring compound present in leguminous plants, especially in soybeans. Chemically it belongs to the isoflavone class and possesses high nutritive value.
A. Laddha, Yogesh A. Kulkarni
semanticscholar   +1 more source

Inclusion Complexes of Daidzein with Cyclodextrin-Based Metal–Organic Framework-1 Enhance Its Solubility and Antioxidant Capacity

AAPS PharmSciTech, 2021
Daidzein, an aglycone-type isoflavone, is useful in the prevention of atherosclerotic cardiovascular diseases. However, the solubility of daidzein remains relatively low even with pharmaceutical interventions (e.g., γ-cyclodextrin inclusion complex).
Y. Inoue, M. Yoshida, Toshinari Ezawa, T. Tanikawa, F. Arce, G. L. See, Junki Tomita, Mitsuaki Suzuki, T. Oguchi   +8 more
semanticscholar   +1 more source

A novel radioimmunoassay for daidzein

Steroids, 1997
A radioimmunoassay for daidzein was established, based on polyclonal antibodies against daidzein-4'-O-(carboxymethyl)ether-BSA. The sensitivity of the assay was 0.4 pg/tube; the intra- and interassay coefficients of variation varied from 4.1 to 11.5% and from 5.6 to 21.7%, respectively, depending upon the method (direct or extraction) and concentration
Herman Adlercreutz, Auli Salakka, Oldrich Lapcik, Kristiina Wähälä, Nawaf Al-Maharik, Richard Hampl   +5 more
openaire   +3 more sources

Daidzein and its Effects on Brain

Current Medicinal Chemistry, 2017
Among naturally occurring isoflavones, soy isoflavones are an important class with various biological activities. Due to their phytoestrogenic structure, their effects on the brain are profound thus making the neurobiological effects of these compounds an active area of research.
Ahmed Touqeer, Javed Sana, Tariq Ameema, Budzyńska Barbara, D Onofrio Grazia, Daglia Maria, Nabavi Seyed Fazel, Nabavi Seyed Mohammad   +7 more
openaire   +3 more sources

The synthesis of daidzein sulfates

Tetrahedron, 2003
The first syntheses of the urinary isoflavone metabolites, daidzein 4'-sulfate, daidzein 7-sulfate and daidzein 4',7-disulfate are described. These syntheses employ a key protecting group strategy, allowing regiospecific sulfation.
Fairley, Brian, Botting, Nigel P., Cassidy, Aedin   +2 more
openaire   +3 more sources

Biotransformation of daidzein ditiglate by microorganisms

Natural Product Research, 2006
Biotransformation of the daidzein ditiglate (2) by fungi, Aspergillus niger and Glomerella cingulata was investigated. Compound 2 was transformed to daidzein (1) by A. niger and G. cingulata. This suggested that compound 2 was converted to compound 1 by hydrolysis at both of the C-7 and C-4' positions.
Mitsuo Miyazawa, Koji Takahashi, Hideo Araki   +2 more
openaire   +3 more sources

In-vivo and in-silico toxicity studies of daidzein: an isoflavone from soy

Drug and chemical toxicology (New York, N.Y. 1978), 2020
Daidzein is a naturally occurring compound belonging to the class isoflavones and found in soya beans and other legumes. Acute oral toxicity was performed as per OECD guideline (TG 423) with slight modifications.
A. Laddha, S. Murugesan, Yogesh A. Kulkarni   +2 more
semanticscholar   +1 more source