Results 221 to 230 of about 24,282 (276)

Daidzein and the daidzein metabolite, equol, enhance adipocyte differentiation and PPARγ transcriptional activity

Journal of Nutritional Biochemistry, 2010
Dietary soy isoflavones have been shown to favorably alter the metabolic phenotypes associated with Type 2 diabetes. However, the identification of direct targets and the underlying molecular mechanisms by which soy isoflaovones exert antidiabetic effects remain elusive.
Ok-Hwan Lee, N Moustaid-Moussa, Neil F Shay   +2 more
exaly   +4 more sources

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A novel radioimmunoassay for daidzein

Steroids, 1997
A radioimmunoassay for daidzein was established, based on polyclonal antibodies against daidzein-4'-O-(carboxymethyl)ether-BSA. The sensitivity of the assay was 0.4 pg/tube; the intra- and interassay coefficients of variation varied from 4.1 to 11.5% and from 5.6 to 21.7%, respectively, depending upon the method (direct or extraction) and concentration
O, Lapcík, R, Hampl, N, al-Maharik, A, Salakka, K, Wähälä, H, Adlercreutz   +5 more
openaire   +2 more sources

Daidzein ameliorates diabetic retinopathy in experimental animals

Life Sciences, 2021
The present study was designed to check the effect of daidzein in the management of diabetic retinopathy.Streptozotocin at dose 55 mg/kg was used for inducing diabetes in rats. After 28 days of diabetic induction, animals were treated with daidzein at dose 25, 50, and 100 mg/kg for the next 28 days.
Ankit P, Laddha, Yogesh A, Kulkarni
openaire   +2 more sources

Daidzein and its Effects on Brain

Current Medicinal Chemistry, 2017
Among naturally occurring isoflavones, soy isoflavones are an important class with various biological activities. Due to their phytoestrogenic structure, their effects on the brain are profound thus making the neurobiological effects of these compounds an active area of research.
Ahmed Touqeer, Javed Sana, Tariq Ameema, Budzyńska Barbara, D Onofrio Grazia, Daglia Maria, Nabavi Seyed Fazel, Nabavi Seyed Mohammad   +7 more
openaire   +3 more sources

Chemical Synthesis of [¹³C]Daidzein

Journal of Medicinal Food, 1999
Pharmacokinetic and metabolic studies of phytoestrogens of the isoflavone class have been hampered by the lack of suitable stable-isotope-labeled analogs. A method for preparation of a [(13)C]-labeled analog of daidzein is described. [2-(13)C]Daidzein was synthesized by reaction of [(13)C]diethoxydimethylaminomethane with 2,4-dihydroxybenzoin.
BARALDI, Pier Giovanni, SPALLUTO GIAMPIERO, CACCIARI, Barbara, ROMAGNOLI, Romeo, SETCHELL KENNETH D. R.   +4 more
openaire   +3 more sources

Biotransformation of daidzein ditiglate by microorganisms

Natural Product Research, 2006
Biotransformation of the daidzein ditiglate (2) by fungi, Aspergillus niger and Glomerella cingulata was investigated. Compound 2 was transformed to daidzein (1) by A. niger and G. cingulata. This suggested that compound 2 was converted to compound 1 by hydrolysis at both of the C-7 and C-4' positions.
Mitsuo, Miyazawa, Koji, Takahashi, Hideo, Araki   +2 more
openaire   +2 more sources

Interaction among protein, daidzein and surfactants in the WPI-based daidzein self-microemulsifying delivery system

Food Chemistry, 2020
The self-microemulsifying delivery system was fabricated by whey protein isolate (WPI), daidzein (Dai) and surfactants, the interaction of WPI, Dai and D-α-Tocopherol polyethylene glycol succinate (TPGS) was hereby studied in the absence or presence of Tween 20.
Huimin Chen, Fujia Yang, Liang Lv, Caili Fu, Xixi Cai, Shaoyun Wang   +5 more
openaire   +2 more sources

Synthesis of D6-daidzein

Journal of Labelled Compounds and Radiopharmaceuticals, 2000
Daidzein, an isoflavone abundant in soy, has various interesting biological properties that have been ascribed potential beneficial effects on human health. The study of these properties and effects of daidzein in general requires that an isotopically labeled reference compound is available for quantitative measurements.
Sirpa Rasku, Kristiina W�h�l�
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Daidzein/cyclodextrin/hydrophilic polymer ternary systems

Drug Development and Industrial Pharmacy, 2011
To evaluate the effect of different cyclodextrins (β-cyclodextrin [β-CD], methyl-β-cyclodextrin [Mβ-CD], or hydroxypropyl-β-cyclodextrin [HPβ-CD]) and/or hydrophilic polymers (carboxymethylcellulose, hydroxypropylmethylcellulose [HPMC], polyethyleneglycol, or polyvinylpyrrolidone [PVP]) on daidzein solubility in water.The corresponding associations ...
Greice Stefani, Borghetti, Angela Pinheiro, Pinto, Ivana Silva, Lula, Rubén Dario, Sinisterra, Helder Ferreira, Teixeira, Valquiria Linck, Bassani   +5 more
openaire   +2 more sources