Results 31 to 40 of about 8,364,200 (274)

ODP392 Persistence with daily growth hormone treatment among pediatric patients with growth hormone deficiency in the UK [PDF]

J Endocr Soc, 2022
Abstract Background Suboptimal adherence to, and persistence with, daily somatropin therapy to treat children with growth hormone deficiency (GHD) has been documented previously, and has also been shown to have negative effects on the growth response ...
Loftus, Jane, Wogen, Jen, Oliveri, David, Benjumea, Darrin, Jhingran, Priti, Chen, Yong, Alvir, Jose, Sanz, Elena Rivero, Kowalik, Jack Charles   +8 more
europepmc   +2 more sources

Experience of switching from a daily to a less frequent administration of injection treatments

PLoS ONE, 2022
Background Daily injections of recombinant human growth hormone are the standard of care to treat growth failure due to pediatric growth hormone deficiency (GHD). While effective, daily injections are burdensome and can compromise adherence.
Jane Loftus, Andrew Yaworsky, Carl L. Roland, Diane Turner-Bowker, Megan McLafferty, Sylvia Su, Roger E. Lamoureux   +6 more
doaj   +2 more sources

Decrease in adiponectin levels correlates to growth response in growth hormone-treated children

, 2009
BACKGROUND/AIMS: Adiponectin is secreted by adipose tissue and circulates in human plasma at high levels. Decreased adiponectin levels are associated with insulin resistance and obesity.
Carlsson, LMS, Swedish, Study Group for Growth Hormone Treatment, Andersson, B, Albertsson-Wikland, K, Carlsson, B, Bjarnason, R   +5 more
core   +3 more sources

Long acting growth hormone (LAGH), an update

Frontiers in Pediatrics, 2023
In 1957, Maurice Raben at Yale was able to isolate and purify growth hormone from cadaveric pituitary glands. Pituitary growth hormone was the only way to treat children with growth hormone (GH) deficiency, until 1985 when recombinant GH became available
Margaret Steiner Grillo, Jacklyn Frank, Paul Saenger   +2 more
doaj   +1 more source

Treatment of Growth Hormone Deficiency via Daily Intravascular Injections in a Child with Bleeding Disorder

Case Reports in Endocrinology, 2021
Objectives. The standard of treatment for pediatric growth hormone deficiency (GHD) is daily subcutaneous recombinant human growth hormone (rhGH) injections. The efficacy of rhGH treatment given as daily intravenous (IV) boluses is not known.
Emir Tas, Serife E. Uzun, Vildan Tas, Juan D. Mejia-Otero   +3 more
doaj   +1 more source

Effect of long-acting growth hormone treatment on endogenous growth hormone secretion in prepubertal patients with idiopathic short stature: A preliminary study

, 2022
Long-acting growth hormone (LAGH) is emerging to be a new preparation for treatment of short stature. We aimed to determine whether 12-month treatment with LAGH in patients with idiopathic short stature has an effect on the nocturnal endogenous growth ...
김호성, 서정환, 최한샘, 권아름, 송경철, 채현욱, Kyungchul Song, Han Saem Choi, Junghwan Suh, Hyun Wook Chae, Ho-Seong Kim, Ahreum Kwon   +11 more
core   +1 more source

Perspectives on long-acting growth hormone therapy in children and adults

Archives of Endocrinology and Metabolism, 2020
Growth hormone therapy with daily injections of recombinant human growth hormone has been available since 1985, and is shown to be safe and effective treatment for short stature in children and for adult growth hormone deficiency. In an effort to produce
Rayhan A. Lal, Andrew R. Hoffman
doaj   +1 more source

Daily production and metabolic clearance of growth hormone in juvenile diabetes mellitus [PDF]

Diabetologia, 1973
Daily production (PR) of human growth hormone (HGH) was calculated in patients with juvenile diabetes and control subjects by determining metabolic clearance rate (MCR) of131I HGH, at equilibrium, and mean endogenous HGH levels throughout a 24 h day. Half hourly sampling or a constant withdrawal pump were used to obtain an integrated mean endogenous ...
M A, Sperling, F, Wollesen, P V, DeLamater   +2 more
openaire   +2 more sources

Impact of adult growth hormone deficiency on daily functioning and well-being [PDF]

BMC Research Notes, 2014
Adult Growth Hormone Deficiency (AGHD) is a debilitating condition resulting from tumors, pituitary surgery, radiation of the head, head injury, or hypothalamic-pituitary disease. This qualitative study was conducted to better understand the multi-faceted impacts and treatment effects of GHD on adult patients' daily lives.Seven focus groups and four ...
Brod, Meryl, Pohlman, Betsy, Højbjerre, Lise, Adalsteinsson, Johan, Rasmussen, Michael   +4 more
openaire   +2 more sources

Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation [PDF]

, 2010
Study found that treatment with recombinant human growth hormone gave significantly greater benefits in stature for children with growth hormone deficiency (GHD), Turner syndrome, Prader–Willi syndrome, chronic renal insufficency, short stature homeobox ...
Bird, A., Baxter, L, Gospodarevskaya, E., K Welch, Cooper, Keith, L Baxter, Frampton, G. K., A Bird, Frampton, GK, Gospodarevskaya, Elena, Gospodarevskaya, E, Welch, K, Bryant, J, Takeda, A, Frampton, G.K., Cooper, K., GK Frampton, Takeda, Andrea, Bird, A, Bryant, J., J Bryant, K Cooper, Welch, Karen, Welch, K., Baxter, L., Takeda, A., Bryant, Jackie, A Takeda, E Gospodarevskaya, Cooper, K   +29 more
core   +1 more source