Results 61 to 70 of about 286,854 (260)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The correlation between the daily incidence of varicella and meteorological factors in Jiangxi province from 2015 to 2021: a surveillance data analysis

Zhongguo gonggong weisheng
ObjectiveTo understand the correlation between the incidence of varicella and meteorological factors in Jiangxi province from 2015 to 2021, and to provide a reference for meteorological prediction and early warning of varicella incidence.
Xing YE, Chengfeng ZHANG, Huijian CHENG, Sheng DING, Weijie FU   +4 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Study on Forecasting Model of Maximum Daily Power Load in Beijing Area

Zhongguo dianli, 2019
The characteristics of maximum daily power load and the dependence of maximum daily power load on meteorological factors are analyzed in this paper based on the records of the power load and auto weather station meteorological data of Beijing from 2009 ...
Yuheng SHI, Na ZHAO, Ling WANG, Lijia XU, Jie ZHOU, Qian LIN, Yuan QIAO   +6 more
doaj   +1 more source

Monitoring and Evaluation of High Temperature and Heat Damage of Summer Maize Based on Remote Sensing Data

应用气象学报, 2020
In the context of global warming, the high temperature heat damage of summer maize occurs frequently in recent years, which seriously affects the yield and quality of corn.
Yang Lei, Han Lijuan, Song Jinling, Li Sen   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Assessing the Volatility of Daily Maximum Temperature across Germany between 1990 and 2022

Atmosphere
Climate change causes a global rise in mean air temperature and an increased frequency of temperature extremes. Recent studies link sharp temperature changes between consecutive days to increased mortality, reduced economic growth, and negative effects ...
Elisa Jordan, Ankit Shekhar, Mana Gharun
doaj   +1 more source

Associations between daily ambient temperature and sedentary time among children 4-6 years old in Mexico City.

PLoS ONE, 2020
BackgroundSedentary behavior is a worldwide public health concern. There is consistent and growing evidence linking sedentary behavior to mortality and morbidity.
Sandy Wong, Alejandra Cantoral, Martha María Téllez-Rojo, Ivan Pantic, Emily Oken, Katherine Svensson, Michael Dorman, Iván Gutiérrez-Avila, Johnathan Rush, Nia McRae, Robert O Wright, Andrea A Baccarelli, Itai Kloog, Allan C Just   +13 more
doaj   +1 more source

July Mean Daily Maximum Temperatures

, 2010
The map shows the mean daily maximum temperatures for July. Maximum temperatures in July are above freezing across all of Canada except for high elevations on Ellesmere Island. Maximum temperatures exceed 25ºC in the valley bottoms of southern British Columbia, across the southern Prairies, in southern Ontario and along the St.
openaire   +1 more source

On forecasting daily summer maximum temperature at Madras

MAUSAM, 1998
Forecasting schemes based on statistical techniques have been developed to forecast daily summer (March-May) maximum temperatures of Madras. A set of optimal number of predictors were chosen from a large number of parameters by employing stepwise forward screening.
openaire   +2 more sources