Results 31 to 40 of about 4,279 (197)

Effect of Dalbavancin on Staphylococcal Biofilms When Administered Alone or in Combination With Biofilm-Detaching Compounds

Frontiers in Microbiology, 2020
Microorganisms grown in biofilms are more resistant to antimicrobial treatment and immune system attacks compared to their planktonic forms. In fact, infections caused by biofilm-forming Staphylococcus aureus and Staphylococcus epidermidis are a large ...
Miglë Žiemytė, Juan C. Rodríguez-Díaz, María P. Ventero, Alex Mira, Alex Mira, María D. Ferrer, María D. Ferrer   +6 more
doaj   +1 more source

Beyond conventional antibiotics for the future treatment of methicillin-resistant Staphylococcus aureus infections: two novel alternatives. [PDF]

, 2012
The majority of antibiotics currently used to treat methicillin-resistant Staphylococus aureus (MRSA) infections target bacterial cell wall synthesis or protein synthesis. Only daptomycin has a novel mode of action.
Devocelle, Marc, Fitzgerald-Hughes, Deirdre, Humphreys, Hilary   +2 more
core   +1 more source

In Vitro Activity of Tedizolid, Dalbavancin, and Ceftobiprole Against Clostridium difficile

Frontiers in Microbiology, 2018
Background:Clostridium difficile (C. difficile) is a major nosocomial pathogen that colonizes in the human gut. Recently, the U.S. FDA approved three new antimicrobial agents against gram-positive bacteria: Tedizolid, Dalbavancin, and Ceftobiprole.
Dana Binyamin, Dana Binyamin, Orna Nitzan, Orna Nitzan, Maya Azrad, Zohar Hamo, Zohar Hamo, Omry Koren, Avi Peretz, Avi Peretz   +9 more
doaj   +1 more source

An in vitro evaluation of the efficacy of tedizolid: implications for the treatment of skin and soft tissue infections [PDF]

, 2018
Skin and soft tissue infections (SSTI) are among the most commonly occurring infections and evidence suggests that these are increasing world-wide.
Aleryan, Muna, Delpech, Pierre, Gemmell, Curtis, Jones, Brian, Lang, Susan   +4 more
core   +2 more sources

Antibiotic resistance mechanisms inform discovery: identification and characterization of a novel amycolatopsis strain producing ristocetin. [PDF]

, 2014
Discovering new antibiotics is a major scientific challenge, made increasingly urgent by the continued development of resistance in bacterial pathogens.
Cheng, Jinhua, Hong, Hee-Jeon, Kwun, Min Jung, Suh, Joo-Won, Truman, Andrew W, Yang, Seung Hwan   +5 more
core   +2 more sources

Comparison of dalbavancin with standard of care in the management of infective endocarditis: efficacy, safety, and cost analysis

International Journal of Infectious Diseases
Objectives: Due to its long half-life, dalbavancin offers benefits for long-duration treatments, especially osteoarticular and infective endocarditis (IE).
Milagros Suárez, Antonio Pérez-Landeiro, Ana Sanjurjo, Olalla Lima, Adrián Sousa, Ana López, Lucía Martínez-Lamas, Xurxo Cabrera, Martín Rubianes, María Teresa Pérez-Rodríguez   +9 more
doaj   +1 more source

Determination of the Elution Capacity of Dalbavancin in Bone Cements: New Alternative for the Treatment of Biofilm-Related Peri-Prosthetic Joint Infections Based on an In Vitro Study

Antibiotics, 2022
Antibiotic-loaded bone cement is the most widely used approach for the treatment of biofilm-induced septic sequelae in orthopedic surgery. Dalbavancin is a lipoglycopeptide that acts against Gram-positive bacteria and has a long half-life, so we aimed to
Mar Sánchez-Somolinos, Marta Díaz-Navarro, Antonio Benjumea, Marta Tormo, José Matas, Javier Vaquero, Patricia Muñoz, Pablo Sanz-Ruíz, María Guembe   +8 more
doaj   +1 more source

Impact of first-line dalbavancin for cellulitis on hospital admissions and costs: A case series

Journal of Global Antimicrobial Resistance
Background: Many patients with cellulitis are treated with oral antibiotics as outpatients, but some require hospital admission for intravenous antibiotics.
Kailey Ben-Sassi, Suhail Sarwar
doaj   +1 more source

Pharmacokinetics/pharmacodynamics of marbofloxacin in a Pasteurella multocida serious murine lung infection model [PDF]

, 2015
The ARRIVE Guidelines Checklist. Animal Research: Reporting In Vivo Experiments.
Changfu Cao, Chaoping Liang, Meizhen Sun, Yan Lu, Ying Qu, Zhenling Zeng, Zhenzhen Qiu   +6 more
core   +2 more sources

Dalbavancin versus standard of care for the treatment of osteomyelitis in adults: A retrospective matched cohort study

Saudi Pharmaceutical Journal, 2020
Objective: To assess the safety and effectiveness of dalbavancin compared to standard of care (SOC) in the treatment of osteomyelitis in adults. Method: A retrospective cohort study of patients with osteomyelitis due to S. aureus treated with dalbavancin
Thamer A. Almangour, Gregory K. Perry, Abdullah A. Alhifany   +2 more
doaj   +1 more source