The hidden cost of dalbavancin: OPAT RN time required in coordination for persons who use drugs
Background: Serious infections in persons who use drugs (PWUD) are rising. Dalbavancin, due to its extended half-life, offers an alternative treatment for patients in whom standard of care antibiotics are not feasible or practical, allowing for reduced ...
Alyse H. Douglass +8 more
doaj +1 more source
Epidemiology and Microbiology of Skin and Soft Tissue Infections: Preliminary Results of a National Registry [PDF]
Skin and soft tissue infections (SSTIs) represent a wide range of clinical conditions characterized by a considerable variety of clinical presentations and severity. Their aetiology can also vary, with numerous possible causative pathogens.
Amendola, Giovanni +44 more
core +1 more source
Efficacy of Novel Antimicrobial Therapies for Treating Staphylococcus Infections in Wistar Rats
The novel semisynthetic lipoglycopeptide dalbavancin has enhanced antibacterial action against a wide range of gram-positive bacteria. This study was conducted to evaluate the efficacy of dalbavancin in treating Staphylococcus Infections in ...
Noman D. Salih.
doaj +1 more source
Dalbavancin is a novel semisynthetic glycopeptide antibiotic that comprises multiple homologs and isomers of similar polarities. However, pharmacokinetic studies have only analyzed the primary components of dalbavancin, namely B0 and B1.
Difeng Zhu +5 more
doaj +1 more source
Background: Our aim was to describe the clinical outcome and safety of the sequential treatment with off-label dalbavancin in patients with spondylodiscitis that is caused by methicillin-resistant Staphylococcus aureus (MRSA). Methods: We retrospectively
Maria Mazzitelli +7 more
doaj +1 more source
Assessment of Minimum Inhibitory Concentrations of Telavancin by Revised Broth Microdilution Method in Phase 3 Hospital-Acquired Pneumonia/Ventilator-Associated Pneumonia Clinical Isolates [PDF]
INTRODUCTION: The broth microdilution method (BMD) for testing telavancin minimum inhibitory concentrations (MICs) was revised (rBMD) in 2014 to improve the accuracy, precision, and reproducibility of the testing method.
Gordon Ralph Corey +4 more
core +1 more source
Saarvienin A—A Novel Glycopeptide with Potent Activity against Drug‐Resistant Bacteria
A structurally distinct glycopeptide, saarvienin A, represents a new family of glycopeptide antibiotics consisting of five sugar/aminosugar units connected to a halogenated peptide core. Saarvienin A overcomes vancomycin resistance and shows strong activity against drug‐resistant Gram‐positive bacteria, in particular, high‐priority pathogens such as ...
Amninder Kaur +7 more
wiley +2 more sources
Efficacy and safety of dalbavancin in the treatment of Gram-positive bacterial infections
Objectives: In this meta-analysis, we assessed the clinical efficacy and safety of dalbavancin compared with commonly used anti-Gram-positive agents. Methods: PubMed, Embase and Cochrane Library databases were searched from inception up to 25 February ...
Yuhang Wang +4 more
doaj +1 more source
Susceptibility testing and reporting of new antibiotics with a focus on tedizolid: an international working group report [PDF]
Inappropriate use and overuse of antibiotics are among the most important factors in resistance development, and effective antibiotic stewardship measures are needed to optimize outcomes.
Ana Cristina Gales +8 more
core +5 more sources
Expert Opinion on Dose Regimen and Therapeutic Drug Monitoring for Long-Term Use of Dalbavancin: Expert Review Panel [PDF]
Background: Dalbavancin is a lipoglycopeptide with a long elimination half-life, currently licensed for the treatment of acute bacterial skin and skin structure infections (ABSSSI) in adults.
Cuervo, Guillermo +10 more
core +1 more source

