Results 91 to 100 of about 1,741,299 (263)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Experimental Cyclic Behavior of Precast Hybrid Beam-Column Connections with Welded Components
International Journal of Concrete Structures and Materials, 2017 Post-earthquake observations revealed that seismic performance of beam-column connections in precast concrete structures affect the overall response extensively.
Sadik Can Girgin +2 more
doaj +1 more source
Vibration based Structural Health Monitoring of a Composite Plate Structure with Multiple Stiffeners [PDF]
, 2010 A vibration based damage identification method is investigated experimentally.\ud The dynamic response of an intact and a locally damaged 16–layer unidirectional\ud carbon fibre PEKK reinforced plate structure with two stiffener sections is considered ...
Akkerman, R. +4 more
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Office and 24-hour heart rate and target organ damage in hypertensive patients [PDF]
, 2012 Background We investigated the association between heart rate and its variability with the parameters that assess vascular, renal and cardiac target organ damage.
Ángel García-García +7 more
core +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Irreversible organ damages in patients with systemic lupus erythematosus. SLICC damage index
Современная ревматология, 2016 The paper presents a literature review demonstrating the importance of using the damage index (DI) for the comprehensive evaluation of the degree of irreversible organ changes in patients with systemic lupus erythematosus (SLE).
E. S. Solovyeva +5 more
doaj +1 more source
Evaluation of the esthetic properties of developmental defects of enamel: a spectrophotometric clinical study [PDF]
, 2015 Objectives. Detailed clinical quantification of optical properties of developmental defect of enamel is possible with spectropho- tometric evaluation. Developmental defects of enamel (DDE) are daily encountered in clinical practice. DDE are an alteration
Corridore, Denise +5 more
core +4 more sources
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Pilot evaluation of the Index Based Flood Insurance in Bihar, India: Lessons of experiences [PDF]
, 2020 The Government of Bihar (GOB) with the help of Government of India (GOI) introduced and implemented various crop insurance programs, to provide protection against losses caused by fluctuations in the output of a crop from one year to another or from one ...
Aheeyar, Mohamed M.M. +2 more
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