Results 111 to 120 of about 79,411 (313)

Modelling damage and failure in carbon/epoxy non-crimp fabric composites including effects of fabric pre-shear [PDF]

open access: yes, 2006
A numerical material model for intra-laminar failure prediction of biaxial non-crimp fabric composites is presented. The model combines the elasto-plastic continuum damage constitutive model proposed by Ladevèze with the intra-laminar matrix failure ...
Greve, L., Pickett, Anthony K.
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Damage-based formability analysis for TWBs [PDF]

open access: yes, 2005
This paper describes a damage-based formability analysis for tailor-welded blanks (TWBs) using an anisotropic damage model and damage criterion for localized necking.
Chan, LC   +7 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Avaliação de deflexões em estruturas de concretoarmado utilizando mecânica do dano

open access: yesRevista IBRACON de Estruturas e Materiais
Este trabalho visa apresentar uma contribuição sobre uma proposta de abordagem para o cálculo de deslocamentos em estruturas de concreto armado em regime de serviço, sendo restrito o estudo ao caso de concretos C20 a C35.
J. J. C. Pituba, R. G. Delalibera
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Mechanics of materials and structures / [PDF]

open access: yes, 1994
A wide range of topics in the area of mechanics of materials and structures are covered in this volume, ranging from analysis to design. There is no special emphasis on a specific area of research.
Bieniek Symposium on Mechanics of Materials and Structures(1993 :University of Virginia)   +4 more
core  

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