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Sensitivity analysis of the probabilistic damage stability regulations for RoPax vessels [PDF]

open access: green, 2008
In the light of the newly developed harmonised probabilistic damage stability regulations, set to come into force in 2009, this article presents a systematic and thorough analysis of the sensitivity of the Attained Subdivision Index with reference to a ...
George Simopoulos   +2 more
openalex   +3 more sources

Advanced damage stability assessment for surface combatants [PDF]

open access: yesOcean Engineering, 2016
One of the major contributors to survivability of a surface combatant is her vulnerability to weapon effects and as such the damage stability characteristics have a direct influence on vulnerability. There are serious concerns about the limitations of the current semi-empirical deterministic criteria in which a combatant’s damage stability is assessed ...
Evangelos Boulougouris   +1 more
exaly   +4 more sources

Regulation of MDM2 Stability After DNA Damage [PDF]

open access: greenJournal of Cellular Physiology, 2015
Cells in our body are constantly exposed to various stresses and threats to their genomic integrity. The tumor suppressor protein p53 plays a critical role in successful defense against these threats by inducing apoptotic cell death or cell cycle arrest.
Jiaqi Li, Manabu Kurokawa
openalex   +4 more sources

Damage Stability of Ships

open access: yesJournal of Marine Science and Engineering, 2023
Ensuring adequate damage stability of ships is essential in ship design and directly contributes to their safe operation [...]
Papanikolaou, Apostolos, Ruponen, Pekka
openaire   +3 more sources

An alternative system for damage stability enhancement [PDF]

open access: yes, 2016
There is an ongoing and continuous initiative to improve the survivability of passenger vessels and in the past increasing safety standards have generally been catered for through the use of design(passive) measures. However, this approach is becoming saturated and any such measures to improve damage stability severly erode ship earning potential and ...
Vassalos, Dracos   +2 more
openaire   +3 more sources

Schizosaccharomyces pombe Rtf2 is important for replication fork barrier activity of RTS1 via splicing of Rtf1

open access: yeseLife, 2023
Arrested replication forks, when restarted by homologous recombination, result in error-prone DNA syntheses and non-allelic homologous recombination. Fission yeast RTS1 is a model fork barrier used to probe mechanisms of recombination-dependent restart ...
Alice M Budden   +6 more
doaj   +1 more source

Replication dynamics of recombination-dependent replication forks

open access: yesNature Communications, 2021
Replication forks that are stalled at obstacles on the DNA template can be restarted by homologous recombination. Here, the authors show replication dynamics during homologous recombination-dependent replication fork restart by combining polymerase usage
Karel Naiman   +5 more
doaj   +1 more source

Live-cell single-molecule tracking highlights requirements for stable Smc5/6 chromatin association in vivo

open access: yeseLife, 2021
The essential Smc5/6 complex is required in response to replication stress and is best known for ensuring the fidelity of homologous recombination. Using single-molecule tracking in live fission yeast to investigate Smc5/6 chromatin association, we show ...
Thomas J Etheridge   +10 more
doaj   +1 more source

CRISPR-Associated Primase-Polymerases are implicated in prokaryotic CRISPR-Cas adaptation

open access: yesNature Communications, 2021
CAPPs are putative Primase-Polymerases associated with CRISPR-Cas operons. Here, the authors show CAPPs genetic and physical association with Cas1 and Cas2, their capacity to function as DNA-dependent DNA primases and DNA polymerases, and that Cas1-Cas2 ...
Katerina Zabrady   +4 more
doaj   +1 more source

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