Results 21 to 30 of about 619,613 (312)
Sensitivity analysis of the probabilistic damage stability regulations for RoPax vessels [PDF]
, 2008 In the light of the newly developed harmonised probabilistic damage stability regulations, set to come into force in 2009, this article presents a systematic and thorough analysis of the sensitivity of the Attained Subdivision Index with reference to a ...
Simopoulos, G. +2 more
core +1 more source
Stability of non-localized responses for damaging materials [PDF]
Vietnam Journal of Mechanics, 2008 This work is devoted to the analysis of the stability of the homogeneous states of a bar made of a brittle strain softening material submitted to a tensile loading. We distinguish two types of damage models: local damage models and gradient damage models. We show that a local damage model necessarily leads to the unstability of the homogeneous response
Marigo, Jean-Jacques, Pham, Kim
openaire +4 more sources
Ship Damage Stability Enhancement through Crashworthiness [PDF]
, 2023 Crashworthiness as one of the Risk Control Options (RCOs) for damage stability enhancement has been around since the 1990s, potentially earlier. Yet, it has never managed to gain inroads for routine use in ship design and operation to enhance ship damage
Hongseok Bae +3 more
core
A nucleotide resolution map of Top2-linked DNA breaks in the yeast and human genome
Nature Communications, 2019 Topoisomerase 2 (Top2) is known to resolve DNA topological stress through double strand breaks (DSBs), yet Top2 inhibition has been reported to result in a significant amount of single-strand breaks (SSBs).
William H. Gittens +5 more
doaj +1 more source
Nature Communications, 2019 The kinase PLK1 has important roles during cell division, including mitotic entry and bipolar spindle formation. Here, the authors show that PLK1 also functions in centromere protection, with loss leading to DNA unwinding by Bloom’s syndrome helicase and
Owen Addis Jones +4 more
doaj +1 more source
Ensuring the Stability of the Genome: DNA Damage Checkpoints [PDF]
The Scientific World JOURNAL, 2001 The cellular response to DNA damage is vital for the cell s ability to maintain genomic integrity. Checkpoint signalling pathways, which induce a cell cycle arrest in response to DNA damage, are an essential component of this process. This is reflected by the functional conservation of these pathways in all eukaryotes from yeast to mammalian cells ...
Christine Latif +2 more
openaire +3 more sources
Seepage-damage coupling study of the stability of water-filled dump slope [PDF]
, 2014 The stability of water-filled dump slope has been one significant geotechnical engineering problem that needs to be urgently resolved. The coupling effects of seepage and damage on the dump slope are critically important for stability analysis.
吕祥锋 +3 more
core +1 more source
Nature Communications, 2016 Werner syndrome is a progeroid disease characterised by genetic instability due to mutations to the WRN helicase/exonuclease. Here the authors define a novel Ku binding motif (KBM) and show that two such motifs facilitate the involvement of WRN in DNA ...
Gabrielle J. Grundy +7 more
doaj +1 more source
Cell Reports, 2020 Summary: Centrosome separation in late G2/ early prophase requires precise spatial coordination that is determined by a balance of forces promoting and antagonizing separation. The major effector of centrosome separation is the kinesin Eg5.
Tom Stiff +5 more
doaj +1 more source
Wellcome Open Research, 2022 Single-molecule localisation microscopy (SMLM) uses software to extract super-resolved positions from microscope images of fluorescent molecules. These localisations can then be used to render super-resolution images or analysed to extract information ...
Antony M. Carr +2 more
doaj +1 more source