Results 31 to 40 of about 619,613 (312)
Biomechanical stability of hernia-damaged abdominal walls
Scientific Reports, 2023 AbstractHernia occurs when the peritoneum and/or internal organs penetrate through a defect in the abdominal wall. Implanting mesh fabrics is a common way to reinforce the repair of hernia-damaged tissues, despite the risks of infection and failure associated with them.
Ali Karrech +2 more
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Reconstruction of near-surface tornado wind fields from forest damage [PDF]
, 2010 Tornado intensity is usually inferred from the damage produced. To foster postevent tornado intensity assessments, the authors present a model to reconstruct near-surface wind fields from forest damage patterns. By comparing the structure of observed and
Dotzek, Nikolai, Beck, Veronika
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Nature Communications, 2018 Chromosome instability is associated with cancer formation. Here the authors identify in cultured human cancer cells a non-canonical DNA bridge breakage pathway leading to chromosome missegregation and rearrangements triggered by sister DNA ...
Ankana Tiwari +2 more
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Mitochondrial damage checkpoint in apoptosis and genome stability [PDF]
FEMS Yeast Research, 2004 Mitochondria perform multiple cellular functions including energy production, cell proliferation and apoptosis. Studies described in this paper suggest a role for mitochondria in maintaining genomic stability. Genomic stability appears to be dependent on mitochondrial functions involved in maintenance of proper intracellular redox status, ATP-dependent
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APC/CCdh1 controls CtIP stability during the cell cycle and in response to DNA damage [PDF]
, 2014 Human cells have evolved elaborate mechanisms for responding to DNA damage to maintain genome stability and prevent carcinogenesis. For instance, the cell cycle can be arrested at different stages to allow time for DNA repair.
Sartori, Alessandro A. +17 more
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HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation
Nature Communications, 2022 Binding to HSP90-CDC37 is essential for the activity of many protein kinases, but its function is unclear. Here, the authors show that HSP90-CDC37 provides a structural platform for the phosphatase PP5 to dephosphorylate a bound kinase, ‘factory ...
Jasmeen Oberoi +6 more
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Regulation of MDM2 Stability After DNA Damage [PDF]
Journal of Cellular Physiology, 2015 Cells in our body are constantly exposed to various stresses and threats to their genomic integrity. The tumor suppressor protein p53 plays a critical role in successful defense against these threats by inducing apoptotic cell death or cell cycle arrest.
Jiaqi, Li, Manabu, Kurokawa
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Non-destructive testing of subsurface damage for early indication of laser-induced damage threshold in fused silica [PDF]
, 2023 Subsurface damage (SSD) in optical components is almost unavoidably caused by mechanical forces involved during grinding and polishing and can be a limiting factor, particularly for applications that require high laser powers.
Munser, Anne-Sophie +6 more
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Nonlinear Dynamic Stability of Cylindrical Reticulated Shells with Initial Damage [PDF]
, 2023 As large-span structures, reticulated shells are widely used in large-scale public building and act as emergency shelters in the event of sudden disasters.
Limin Tian +6 more
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Molecular basis for DNA repair synthesis on short gaps by mycobacterial Primase-Polymerase C
Nature Communications, 2020 Mycobacteria Prim-PolC performs short gap synthesis following removal of lesions during excision repair. Here the authors resolve crystal structures of pre- and post-catalytic Prim-PolC complexes bound to gapped DNA substrates to define its mechanism.
Nigel C. Brissett +7 more
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