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Damage Stability of Ships [PDF]
Journal of Marine Science and Engineering, 2023 Ensuring adequate damage stability of ships is essential in ship design and directly contributes to their safe operation [...]
Papanikolaou, Apostolos, Ruponen, Pekka
openaire +4 more sources
An alternative system for damage stability enhancement [PDF]
, 2016 There is an ongoing and continuous initiative to improve the survivability of passenger vessels and in the past increasing safety standards have generally been catered for through the use of design(passive) measures. However, this approach is becoming saturated and any such measures to improve damage stability severly erode ship earning potential and ...
Vassalos, Dracos +2 more
core +5 more sources
eLife, 2023 Arrested replication forks, when restarted by homologous recombination, result in error-prone DNA syntheses and non-allelic homologous recombination. Fission yeast RTS1 is a model fork barrier used to probe mechanisms of recombination-dependent restart ...
Alice M Budden +6 more
doaj +1 more source
GOALDS – Goal Based Damaged Stability: Collision and Grounding Damages [PDF]
, 2011 The present paper outlines the current status of work of the EU funded, FP7 project GOALDS (Goal Based Damaged Stability, 2009-2012), which aims at addressing shortcomings of SOLAS 2009 with respect to the survivability assessment of passenger ships by state of the art scientific methods, formulating a rational, risk-based regulatory framework ...
Papanikolaou A. +2 more
openaire +2 more sources
Replication dynamics of recombination-dependent replication forks
Nature Communications, 2021 Replication forks that are stalled at obstacles on the DNA template can be restarted by homologous recombination. Here, the authors show replication dynamics during homologous recombination-dependent replication fork restart by combining polymerase usage
Karel Naiman +5 more
doaj +1 more source
CRISPR-Associated Primase-Polymerases are implicated in prokaryotic CRISPR-Cas adaptation
Nature Communications, 2021 CAPPs are putative Primase-Polymerases associated with CRISPR-Cas operons. Here, the authors show CAPPs genetic and physical association with Cas1 and Cas2, their capacity to function as DNA-dependent DNA primases and DNA polymerases, and that Cas1-Cas2 ...
Katerina Zabrady +4 more
doaj +1 more source
eLife, 2021 The essential Smc5/6 complex is required in response to replication stress and is best known for ensuring the fidelity of homologous recombination. Using single-molecule tracking in live fission yeast to investigate Smc5/6 chromatin association, we show ...
Thomas J Etheridge +10 more
doaj +1 more source
Inhibition of MRN activity by a telomere protein motif
Nature Communications, 2021 Telomeres suppress the DNA damage response at chromosome ends. Here the authors show that in budding yeast the activity of the MRX complex in DNA repair and DNA damage signaling is inhibited by telomeric protein Rif2 via a short motif at the N-terminus.
Freddy Khayat +11 more
doaj +1 more source
Royal Society Open Science, 2021 Unlike bacteria, mammalian cells need to complete DNA replication before segregating their chromosomes for the maintenance of genome integrity. Thus, cells have evolved efficient pathways to restore stalled and/or collapsed replication forks during S ...
Camelia Mocanu, Kok-Lung Chan
doaj +1 more source
Damage stability of passenger ships : smart methods to identify critical scenarios [PDF]
, 2021 The damaged stability assessment for a passenger ship is a process requiring the simulation of multiple damage scenarios. Nevertheless, due to the stochastic nature of both the damage stability framework and the irregular waves environment, a ...
Boulougouris, Evangelos +4 more
core +2 more sources