Results 61 to 70 of about 619,613 (312)
Design implications of the new harmonised probabilistic damage stability regulations [PDF]
, 2007 In anticipation of the forthcoming new harmonised regulations for damage stability, SOLAS Chapter II-1, proposed in IMO MSC 80 and due for enforcement in 2009, a number of ship owners and consequentially yards and classification societies are venturing ...
York, Anthony +4 more
core
Potency and stability of C terminal truncated human epidermal growth factor [PDF]
, 2000 INTRODUCTION: Epidermal growth factor (EGF) is normally present as EGF(1-53). A variety of C terminal truncated forms have been used in preliminary trials for treating gastrointestinal injury but their relative potency and stability when used in a ...
Lakhoo, K +15 more
core +1 more source
Centromere protection requires strict mitotic inactivation of the Bloom syndrome helicase complex
Nature CommunicationsThe BTRR (BLM/TOP3A/RMI1/RMI2) complex resolves DNA replication and recombination intermediates to maintain genome stability. Alongside PICH, they target mitotic DNA intertwinements, known as ultrafine DNA bridges, facilitating chromosome segregation ...
María Fernández-Casañas +8 more
doaj +1 more source
Cell Reports, 2015 53BP1 plays multiple roles in mammalian DNA damage repair, mediating pathway choice and facilitating DNA double-strand break repair in heterochromatin. Although it possesses a C-terminal BRCT2 domain, commonly involved in phospho-peptide binding in other
Robert A. Baldock +7 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Probabilistic Damage Stability of Ro-Ro Ships [PDF]
, 2008 The purpose of this thesis is to investigate the probabilistic damage stability of Ro-Ro ferries with regard to their subdivision based on the probabilistic damage stability ...
BOCCADAMO, GUIDO
core
Anisotropic damage mechanics as a novel approach to improve pre-and post-failure borehole stability analysis [PDF]
, 2013 Anisotropic damage distribution and evolution have a profound effect on borehole stress concentrations. Damage evolution is an irreversible process that is not adequately described within classical equilibrium thermodynamics.
Karrech, Ali +2 more
core +1 more source
Molecular Basis for DNA Double-Strand Break Annealing and Primer Extension by an NHEJ DNA Polymerase
Cell Reports, 2013 Nonhomologous end-joining (NHEJ) is one of the major DNA double-strand break (DSB) repair pathways. The mechanisms by which breaks are competently brought together and extended during NHEJ is poorly understood.
Nigel C. Brissett +5 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Stability Assessment of Drill Ship Using Probabilistic Damage Stability Analysis [PDF]
, 2019 Drill ship is a ship-shaped structure with a drilling unit at its center and with oil compartments, which is moored and kept in position using anchors.
Mohan, Poonam +3 more
core +2 more sources