Results 31 to 40 of about 172,653 (302)
Maintaining Genome Stability in Defiance of Mitotic DNA Damage [PDF]
Frontiers in Genetics, 2016 The implementation of decisions affecting cell viability and proliferation is based on prompt detection of the issue to be addressed, formulation and transmission of a correct set of instructions and fidelity in the execution of orders. While the first and the last are purely mechanical processes relying on the faithful functioning of single proteins ...
Ferrari, Stefano, Gentili, Christian
openaire +4 more sources
DNA damage can alter the stability of nucleosomes: Effects are dependent on damage type [PDF]
Proceedings of the National Academy of Sciences, 1997 We have investigated the effects of DNA damage by (±)- anti -benzo[ a ]pyrene diol epoxide (BPDE) and UV light on the formation of a positioned nucleosome in the Xenopus borealis 5S rRNA gene.
Mann, David B +2 more
openaire +3 more sources
Dynamic behaviours of damaged stability for floating energy storage unit after accidental collision [PDF]
, 2020 The transient dynamic behaviour of floating energy storage unit (FESU) is a result of coupling between three non-linear effects, which are sloshing of floodwater, wave loading, and FESU dynamics.
Chong, Wen Tong +7 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2021 Cellular function is highly dependent on genomic stability, which is mainly ensured by two cellular mechanisms: the DNA damage response (DDR) and the Spindle Assembly Checkpoint (SAC). The former provides the repair of damaged DNA, and the latter ensures
Fernando Luna-Maldonado +4 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Pipeline Burst–Related Soil Stability in Collapse Condition
, 2022 Underground water main leakage is one of the main causes of instability of soils and sinkholes. In the event of a water main burst, the pressure is upward and hence the soil layer should be analyzed for blowout stability.
Mahalingasivam, Kiritharan +3 more
core +1 more source
Damage stability evaluation of polar navigation vessels under ice accumulation
Zhongguo Jianchuan YanjiuObjectiveWith the gradual reduction in Arctic sea ice extent and the continuous expansion of polar shipping routes, navigation activities in high-latitude areas have increased significantly.
Junfeng GUO +5 more
doaj +1 more source
Advances in Civil Engineering, 2020 Carbon fiber-reinforced polymer/plastic (CFRP) composites bear attractive performance in resistance to tension, fatigue, and corrosion and, thus, have been recognized as a promising candidate for repairing and strengthening steel structures in ...
Bin Li, Hua Luo, Xianqiao Wang
doaj +1 more source
Time domain modeling and simulation of warship flooding process based on counter-flooding activities
Zhongguo Jianchuan Yanjiu, 2022 ObjectivesWarship damage flooding is an interactive process between progressive flooding and counter-flooding measures under battle-damaged conditions. Traditional damage stability theory cannot simulate the influence of counter-flooding measures on the ...
Shiyao WANG +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source