Results 1 to 10 of about 291,465 (197)

Differentiating Damp‐Heat and Cold‐Damp Diarrhea in Rat Models via Gut Microbiota Dysbiosis and Short‐Chain Fatty Acid Profiling [PDF]

open access: yesMicrobiologyOpen
On the basis of gut microbiota and short‐chain fatty acids (SCFAs), this study aims to identify diagnostic biomarkers for damp‐heat diarrhea and cold‐damp diarrhea. Rat models of damp‐heat diarrhea and cold‐damp diarrhea were established. Changes in body
Hao Zhang   +5 more
doaj   +2 more sources

EP300 promotes ferroptosis via HSPA5 acetylation in pancreatic cancer

open access: yesScientific Reports, 2023
Ferroptosis is a form of regulated cell death characterized by oxidative injury-induced lipid peroxidation. However, the detailed protein post-translational modification regulatory mechanism of ferroptosis remains largely unknown.
Yuan Wang   +5 more
doaj   +1 more source

Extracellular self-DNA induces local inhibition of growth, regulates production of reactive oxygen species, and gene expression in rice roots

open access: yesBiologia Plantarum, 2023
The capacity of extracellular self-DNA (esDNA) to inhibit growth is getting more research attention as this could be explored for several purposes, including the development of specific bioherbicides.
T. O. S. TJIA   +4 more
doaj   +1 more source

DAMPs, ageing, and cancer: The ‘DAMP Hypothesis’ [PDF]

open access: yesAgeing Research Reviews, 2015
Ageing is a complex and multifactorial process characterized by the accumulation of many forms of damage at the molecular, cellular, and tissue level with advancing age. Ageing increases the risk of the onset of chronic inflammation-associated diseases such as cancer, diabetes, stroke, and neurodegenerative disease.
Jin, Huang   +6 more
openaire   +2 more sources

ACSS2-mediated NF-κB activation promotes alkaliptosis in human pancreatic cancer cells

open access: yesScientific Reports, 2023
Alkaliptosis is a recently discovered type of pH-dependent cell death used for tumor therapy. However, its underlying molecular mechanisms and regulatory networks are largely unknown.
Dongwen Que   +4 more
doaj   +1 more source

HMGB1 is a mediator of cuproptosis-related sterile inflammation

open access: yesFrontiers in Cell and Developmental Biology, 2022
Cuproptosis is a recently recognized modality of cell death driven by intracellular copper-dependent mitochondrial stress. However, the mediators of the sterile inflammatory response to cuproptotic death are undetermined.
Jiao Liu   +4 more
doaj   +1 more source

An independent predictor of poor prognosis in locally advanced rectal cancer: rs867228 in formyl peptide receptor 1 (FPR1)

open access: yesOncoImmunology, 2021
Formyl peptide receptor 1 (FPR1) plays a key regulatory role in innate and adaptive immunity. Recently, we reported that the CC genotype of FPR1-E346A (rs867228, c. 1037 A > C) is an independent biomarker for patients with locally advanced rectal cancer (
Shu-Fen Chiang   +5 more
doaj   +1 more source

Risk factors for moisture damage presence and severity in Finnish homes

open access: yesBuildings & Cities, 2023
Moisture-damaged buildings are a prominent issue in Finland, but with limited information on damage prevalence, degree of severity and risk factors. This paper analyses 14,996 Finnish detached and semidetached houses that have undergone a standardised ...
Jonathon Taylor   +7 more
doaj   +1 more source

The dark side of ferroptosis in pancreatic cancer

open access: yesOncoImmunology, 2021
Drug-induced ferroptosis, an iron-dependent regulatory necrosis, has been proposed for the therapy of pancreatic ductal adenocarcinoma. However, genetically engineered mouse models have revealed that high-iron diets or deletion of pancreatic GPX4 (a key ...
Jiao Liu   +4 more
doaj   +1 more source

Puddling by Female Florida Tiger Swallowtail Butterflies, \u3ci\u3ePapillo Glaucus Australis\u3c/i\u3e (Lepidoptera: Papilionidae) [PDF]

open access: yes, 2017
(excerpt) Many species from all families of Rhopaloccra have been reported to drink water (Norris 1936). Bates (1863) noted that, in the Amazon, 80 species from 22 genera flocked about the damp edges of water and, with very few exceptions, all of these ...
Scriber, J. Mark
core   +2 more sources

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